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Atmospheric heating rate due to black carbon aerosols: Uncertainties and impact factors 期刊论文
ATMOSPHERIC RESEARCH, 2020, 240
作者:  Lu, Qiao;  Liu, Chao;  Zhao, Delong;  Zeng, Chen;  Li, Jing;  Lu, Chunsong;  Wang, Jiandong;  Zhu, Bin
收藏  |  浏览/下载:35/0  |  提交时间:2020/08/18
Black carbon  Radiative forcing  Heating rate  Vertical distribution  
Remarkable nucleation and growth of ultrafine particles from vehicular exhaust 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (7) : 3427-3432
作者:  Guo, Song;  Hu, Min;  Peng, Jianfei;  Wu, Zhijun;  Zamora, Misti L.;  Shang, Dongjie;  Du, Zhuofei;  Zheng, Jing;  Fang, Xin;  Tang, Rongzhi;  Wu, Yusheng;  Zeng, Limin;  Shuai, Shijin;  Zhang, Wenbin;  Wang, Yuan;  Ji, Yuemeng;  Li, Yixin;  Zhang, Annie L.;  Wang, Weigang;  Zhang, Fang;  Zhao, Jiayun;  Gong, Xiaoli;  Wang, Chunyu;  Molina, Mario J.;  Zhang, Renyi
收藏  |  浏览/下载:12/0  |  提交时间:2020/05/13
new particle formation  nucleation  ultrafine particles  growth  organics  
Improved protein structure prediction using potentials from deep learning 期刊论文
NATURE, 2020, 577 (7792) : 706-+
作者:  Ma, Runze;  Cao, Duanyun;  Zhu, Chongqin;  Tian, Ye;  Peng, Jinbo;  Guo, Jing;  Chen, Ji;  Li, Xin-Zheng;  Francisco, Joseph S.;  Zeng, Xiao Cheng;  Xu, Li-Mei;  Wang, En-Ge;  Jiang, Ying
收藏  |  浏览/下载:142/0  |  提交时间:2020/07/03

Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence(1). This problem is of fundamental importance as the structure of a protein largely determines its function(2)  however, protein structures can be difficult to determine experimentally. Considerable progress has recently been made by leveraging genetic information. It is possible to infer which amino acid residues are in contact by analysing covariation in homologous sequences, which aids in the prediction of protein structures(3). Here we show that we can train a neural network to make accurate predictions of the distances between pairs of residues, which convey more information about the structure than contact predictions. Using this information, we construct a potential of mean force(4) that can accurately describe the shape of a protein. We find that the resulting potential can be optimized by a simple gradient descent algorithm to generate structures without complex sampling procedures. The resulting system, named AlphaFold, achieves high accuracy, even for sequences with fewer homologous sequences. In the recent Critical Assessment of Protein Structure Prediction(5) (CASP13)-a blind assessment of the state of the field-AlphaFold created high-accuracy structures (with template modelling (TM) scores(6) of 0.7 or higher) for 24 out of 43 free modelling domains, whereas the next best method, which used sampling and contact information, achieved such accuracy for only 14 out of 43 domains. AlphaFold represents a considerable advance in protein-structure prediction. We expect this increased accuracy to enable insights into the function and malfunction of proteins, especially in cases for which no structures for homologous proteins have been experimentally determined(7).


  
Coupled Snow and Frozen Ground Physics Improves Cold Region Hydrological Simulations: An Evaluation at the upper Yangtze River Basin (Tibetan Plateau) 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (23) : 12985-13004
作者:  Qi, Jia;  Wang, Lei;  Zhou, Jing;  Song, Lei;  Li, Xiuping;  Zeng, Tian
收藏  |  浏览/下载:8/0  |  提交时间:2020/02/17
Coupled Snow and Frozen Ground Physics Improves Cold Region Hydrological Simulations: An Evaluation at the upper Yangtze River Basin (Tibetan Plateau) 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019
作者:  Qi, Jia;  Wang, Lei;  Zhou, Jing;  Song, Lei;  Li, Xiuping;  Zeng, Tian
收藏  |  浏览/下载:8/0  |  提交时间:2020/02/17
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Shi, Yulin;  Fan, Songqing;  Wu, Mengge;  Zuo, Zhixiang;  Li, Xingyang;  Jiang, Liping;  Shen, Qiushuo;  Xu, Peifang;  Zeng, Lin;  Zhou, Yongchun;  Huang, Yunchao;  Yang, Zuozhang;  Zhou, Jumin;  Gao, Jing;  Zhou, Hu;  Xu, Shuhua;  Ji, Hongbin;  Shi, Peng;  Wu, Dong-Dong;  Yang, Cuiping;  Chen, Yongbin
收藏  |  浏览/下载:20/0  |  提交时间:2019/11/27
A method to identify trace sulfated IgG N-glycans as biomarkers for rheumatoid arthritis 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Wang, Jing-Rong;  Gao, Wei-Na;  Grimm, Rudolf;  Jiang, Shibo;  Liang, Yong;  Ye, Hua;  Li, Zhan-Guo;  Yau, Lee-Fong;  Huang, Hao;  Liu, Ju;  Jiang, Min;  Meng, Qiong;  Tong, Tian-Tian;  Huang, Hai-Hui;  Lee, Stephanie;  Zeng, Xing;  Liu, Liang;  Jiang, Zhi-Hong
收藏  |  浏览/下载:18/0  |  提交时间:2019/11/27
Strain Rate Distribution in South-Central Tibet From Two Decades of InSAR and GPS 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2019, 46 (10) : 5170-5179
作者:  Wang, Hua;  Wright, Tim J.;  Liu-Zeng, Jing;  Peng, Lincai
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/26
Surface erythemal UV irradiance in the continental United States derived from ground-based and OMI observations: quality assessment, trend analysis and sampling issues 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (4) : 2165-2181
作者:  Zhang, Huanxin;  Wang, Jun;  Garcia, Lorena Castro;  Zeng, Jing;  Dennhardt, Connor;  Liu, Yang;  Krotkov, Nickolay A.
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/09
Efficient N2O5 uptake and NO3 oxidation in the outflow of urban Beijing 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2018, 18 (13) : 9705-9721
作者:  Wang, Haichao;  Lu, Keding;  Guo, Song;  Wu, Zhijun;  Shang, Dongjie;  Tan, Zhaofeng;  Wang, Yujue;  Le Breton, Michael;  Lou, Shengrong;  Tang, Mingjin;  Wu, Yusheng;  Zhu, Wenfei;  Zheng, Jing;  Zeng, Limin;  Hallquist, Mattias;  Hu, Min;  Zhang, Yuanhang
收藏  |  浏览/下载:17/0  |  提交时间:2019/04/09