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Characterization of organic aerosol across the global remote troposphere: a comparison of ATom measurements and global chemistry models 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (8) : 4607-4635
作者:  Hodzic, Alma;  Campuzano-Jost, Pedro;  Bian, Huisheng;  Chin, Mian;  Colarco, Peter R.;  Day, Douglas A.;  Froyd, Karl D.;  Heinold, Bernd;  Jo, Duseong S.;  Katich, Joseph M.;  Kodros, John K.;  Nault, Benjamin A.;  Pierce, Jeffrey R.;  Ray, Eric;  Schacht, Jacob;  Schill, Gregory P.;  Schroder, Jason C.;  Schwarz, Joshua P.;  Sueper, Donna T.;  Tegen, Ina;  Tilmes, Simone;  Tsigaridis, Kostas;  Yu, Pengfei;  Jimenez, Jose L.
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/02
Feasible alternatives to green growth 期刊论文
NATURE SUSTAINABILITY, 2020, 3 (4) : 329-335
作者:  D&;  39;Alessandro, Simone
收藏  |  浏览/下载:3/0  |  提交时间:2020/05/13
Global gene flow releases invasive plants from environmental constraints on genetic diversity 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (8) : 4218-4227
作者:  Smith, Annabel L.;  Hodkinson, Trevor R.;  Villellas, Jesus;  Catford, Jane A.;  Csergo, Anna Maria;  Blomberg, Simone P.;  Crone, Elizabeth E.;  Ehrlen, Johan;  Garcia, Maria B.;  Laine, Anna-Liisa;  Roach, Deborah A.;  Salguero-Gomez, Roberto;  Wardle, Glenda M.;  Childs, Dylan Z.;  Elderd, Bret D.;  Finn, Alain;  Munne-Bosch, Sergi;  Baudraz, Maude E. A.;  Bodis, Judit;  Brearley, Francis Q.;  Bucharova, Anna;  Caruso, Christina M.;  Duncan, Richard P.;  Dwyerh, Johnm.;  Gooden, Ben;  Groenteman, Ronny;  Hamre, Liv Norunn;  Helm, Aveliina;  Kelly, Ruth;  Laanisto, Lauri;  Lonati, Michele;  Moore, Joslin L.;  Morales, Melanie;  Olsen, Siri Lie;  Partel, Meelis;  Petry, William K.;  Ramula, Satu;  Rasmussen, Pil U.;  Enri, Simone Ravetto;  Roeder, Anna;  Roscher, Christiane;  Saastamoinen, Marjo;  Tack, Ayco J. M.;  Topper, Joachim Paul;  Vose, Gregory E.;  Wandrag, Elizabeth M.;  Wingler, Astrid;  Buckley, Yvonne M.
收藏  |  浏览/下载:7/0  |  提交时间:2020/05/13
plant invasion  adaptation  global change  population genetics  demography  
A machine learning examination of hydroxyl radical differences among model simulations for CCMI-1 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (3) : 1341-1361
作者:  Nicely, Julie M.;  Duncan, Bryan N.;  Hanisco, Thomas F.;  Wolfe, Glenn M.;  Salawitch, Ross J.;  Deushi, Makoto;  Haslerud, Amund S.;  Joeckel, Patrick;  Josse, Beatrice;  Kinnison, Douglas E.;  Klekociuk, Andrew;  Manyin, Michael E.;  Marecal, Virginie;  Morgenstern, Olaf;  Murray, Lee T.;  Myhre, Gunnar;  Oman, Luke D.;  Pitari, Giovanni;  Pozzer, Andrea;  Quaglia, Ilaria;  Revell, Laura E.;  Rozanov, Eugene;  Stenke, Andrea;  Stone, Kane;  Strahan, Susan;  Tames, Simone;  Tost, Holger;  Westervelt, Daniel M.;  Zeng, Guang
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/02
Synthesis of rare sugar isomers through site-selective epimerization 期刊论文
NATURE, 2020: 403-+
作者:  Jackson, Hartland W.;  Fischer, Jana R.;  Zanotelli, Vito R. T.;  Ali, H. Raza;  Mechera, Robert;  Soysal, Savas D.;  Moch, Holger;  Muenst, Simone;  Varga, Zsuzsanna;  Weber, Walter P.;  Bodenmiller, Bernd
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/03

Glycans have diverse physiological functions, ranging from energy storage and structural integrity to cell signalling and the regulation of intracellular processes(1). Although biomass-derived carbohydrates (such as d-glucose, d-xylose and d-galactose) are extracted on commercial scales, and serve as renewable chemical feedstocks and building blocks(2,3), there are hundreds of distinct monosaccharides that typically cannot be isolated from their natural sources and must instead be prepared through multistep chemical or enzymatic syntheses(4,5). These '  rare'  sugars feature prominently in bioactive natural products and pharmaceuticals, including antiviral, antibacterial, anticancer and cardiac drugs(6,7). Here we report the preparation of rare sugar isomers directly from biomass carbohydrates through site-selective epimerization reactions. Mechanistic studies establish that these reactions proceed under kinetic control, through sequential steps of hydrogen-atom abstraction and hydrogen-atom donation mediated by two distinct catalysts. This synthetic strategy provides concise and potentially extensive access to this valuable class of natural compounds.


Various rare sugars that cannot be isolated from natural sources are synthesized using light-driven epimerization, a process which may find application in other synthetic scenarios.


  
Collaborative Research: CubeSat Ideas Lab: Space Weather Atmospheric Reconfigurable Multiscale Experiment (SWARM-EX) CubeSats 项目
项目编号:1936512; 经费:75816(USD); 起止日期:2020 / dc_date_end
项目负责人:  Simone D&;  39;Amico (Principal Investigator)
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses 期刊论文
SCIENCE, 2019, 366 (6470) : 1216-+
作者:  Steichen, Jon M.;  Lin, Ying-Cing;  Havenar-Daughton, Colin;  Pecetta, Simone;  Ozorowski, Gabriel;  Willis, Jordan R.;  Toy, Laura;  Sok, Devin;  Liguori, Alessia;  Kratochvil, Sven;  Torres, Jonathan L.;  Kalyuzhniy, Oleksandr;  Melzi, Eleonora;  Kulp, Daniel W.;  Raemisch, Sebastian;  Hu, Xiaozhen;  Bernard, Steffen M.;  Georgeson, Erik;  Phelps, Nicole;  Adachi, Yumiko;  Kubitz, Michael;  Landais, Elise;  Umotoy, Jeffrey;  Robinson, Amanda;  Briney, Bryan;  Wilson, Ian A.;  Burton, Dennis R.;  Ward, Andrew B.;  Crotty, Shane;  Batista, Facundo D.;  Schief, William R.
收藏  |  浏览/下载:11/0  |  提交时间:2020/02/17
Dynamics and genomic landscape of CD8(+) T cells undergoing hepatic priming 期刊论文
NATURE, 2019, 574 (7777) : 200-+
作者:  Benechet, Alexandre P.;  De Simone, Giorgia;  Di Lucia, Pietro;  Cilenti, Francesco;  Barbiera, Giulia;  Le Bert, Nina;  Fumagalli, Valeria;  Lusito, Eleonora;  Moalli, Federica;  Bianchessi, Valentina;  Andreata, Francesco;  Zordan, Paola;  Bono, Elisa;  Giustini, Leonardo;  Bonilla, Weldy V.;  Bleriot, Camille;  Kunasegaran, Kamini;  Gonzalez-Aseguinolaza, Gloria;  Pinschewer, Daniel D.;  Kennedy, Patrick T. F.;  Naldini, Luigi;  Kuka, Mirela;  Ginhoux, Florent;  Cantore, Alessio;  Bertoletti, Antonio;  Ostuni, Renato;  Guidotti, Luca G.;  Iannacone, Matteo
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Collaborative Research: CubeSat Ideas Lab: VIrtual Super-resolution Optics with Reconfigurable Swarms (VISORS) 项目
项目编号:1936542; 经费:56958(USD); 起止日期:2019 / dc_date_end
项目负责人:  Simone D&;  39;Amico (Principal Investigator)
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Observations and hypotheses related to low to middle free tropospheric aerosol, water vapor and altocumulus cloud layers within convective weather regimes: a SEAC(4)RS case study 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (17) : 11413-11442
作者:  Reid, Jeffrey S.;  Posselt, Derek J.;  Kaku, Kathleen;  Holz, Robert A.;  Chen, Gao;  Eloranta, Edwin W.;  Kuehn, Ralph E.;  Woods, Sarah;  Zhang, Jianglong;  Anderson, Bruce;  Bui, T. Paul;  Diskin, Glenn S.;  Minnis, Patrick;  Newchurch, Michael J.;  Tanelli, Simone;  Trepte, Charles R.;  Thornhill, K. Lee;  Ziemba, Luke D.
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27