GSTDTAP

浏览/检索结果: 共12条,第1-10条 帮助

限定条件    
已选(0)清除 条数/页:   排序方式:
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike 期刊论文
Science, 2020
作者:  Michael Schoof;  Bryan Faust;  Reuben A. Saunders;  Smriti Sangwan;  Veronica Rezelj;  Nick Hoppe;  Morgane Boone;  Christian B. Billesbølle;  Cristina Puchades;  Caleigh M. Azumaya;  Huong T. Kratochvil;  Marcell Zimanyi;  Ishan Deshpande;  Jiahao Liang;  Sasha Dickinson;  Henry C. Nguyen;  Cynthia M. Chio;  Gregory E. Merz;  Michael C. Thompson;  Devan Diwanji;  Kaitlin Schaefer;  Aditya A. Anand;  Niv Dobzinski;  Beth Shoshana Zha;  Camille R. Simoneau;  Kristoffer Leon;  Kris M. White;  Un Seng Chio;  Meghna Gupta;  Mingliang Jin;  Fei Li;  Yanxin Liu;  Kaihua Zhang;  David Bulkley;  Ming Sun;  Amber M. Smith;  Alexandrea N. Rizo;  Frank Moss;  Axel F. Brilot;  Sergei Pourmal;  Raphael Trenker;  Thomas Pospiech;  Sayan Gupta;  Benjamin Barsi-Rhyne;  Vladislav Belyy;  Andrew W. Barile-Hill;  Silke Nock;  Yuwei Liu;  Nevan J. Krogan;  Corie Y. Ralston;  Danielle L. Swaney;  Adolfo García-Sastre;  Melanie Ott;  Marco Vignuzzi;  QCRG Structural Biology Consortium4‡;  Peter Walter;  Aashish Manglik
收藏  |  浏览/下载:15/0  |  提交时间:2020/12/22
Multifunctional products of isoprene oxidation in polluted atmosphere and their contribution to SOA 期刊论文
Geophysical Research Letters, 2020
作者:  Z. N. Xu;  W. Nie;  X. G. Chi;  P. Sun;  D. D. Huang;  C. Yan;  J. Krechmer;  P. L. Ye;  Z. Xu;  X. M. Qi;  C.J. Zhu;  Y. L. Liu;  Y. Y. Li;  T. Y. Wang;  L. Wang;  X. Huang;  R. Z. Tang;  S. Guo;  G. L. Xiu;  Q. Y. Fu;  D. Worsnop;  A. J. Ding
收藏  |  浏览/下载:16/0  |  提交时间:2020/12/07
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms 期刊论文
Science, 2020
作者:  David E. Gordon;  Joseph Hiatt;  Mehdi Bouhaddou;  Veronica V. Rezelj;  Svenja Ulferts;  Hannes Braberg;  Alexander S. Jureka;  Kirsten Obernier;  Jeffrey Z. Guo;  Jyoti Batra;  Robyn M. Kaake;  Andrew R. Weckstein;  Tristan W. Owens;  Meghna Gupta;  Sergei Pourmal;  Erron W. Titus;  Merve Cakir;  Margaret Soucheray;  Michael McGregor;  Zeynep Cakir;  Gwendolyn Jang;  Matthew J. O’Meara;  Tia A. Tummino;  Ziyang Zhang;  Helene Foussard;  Ajda Rojc;  Yuan Zhou;  Dmitry Kuchenov;  Ruth Hüttenhain;  Jiewei Xu;  Manon Eckhardt;  Danielle L. Swaney;  Jacqueline M. Fabius;  Manisha Ummadi;  Beril Tutuncuoglu;  Ujjwal Rathore;  Maya Modak;  Paige Haas;  Kelsey M. Haas;  Zun Zar Chi Naing;  Ernst H. Pulido;  Ying Shi;  Inigo Barrio-Hernandez;  Danish Memon;  Eirini Petsalaki;  Alistair Dunham;  Miguel Correa Marrero;  David Burke;  Cassandra Koh;  Thomas Vallet;  Jesus A. Silvas;  Caleigh M. Azumaya;  Christian Billesbølle;  Axel F. Brilot;  Melody G. Campbell;  Amy Diallo;  Miles Sasha Dickinson;  Devan Diwanji;  Nadia Herrera;  Nick Hoppe;  Huong T. Kratochvil;  Yanxin Liu;  Gregory E. Merz;  Michelle Moritz;  Henry C. Nguyen;  Carlos Nowotny;  Cristina Puchades;  Alexandrea N. Rizo;  Ursula Schulze-Gahmen;  Amber M. Smith;  Ming Sun;  Iris D. Young;  Jianhua Zhao;  Daniel Asarnow;  Justin Biel;  Alisa Bowen;  Julian R. Braxton;  Jen Chen;  Cynthia M. Chio;  Un Seng Chio;  Ishan Deshpande;  Loan Doan;  Bryan Faust;  Sebastian Flores;  Mingliang Jin;  Kate Kim;  Victor L. Lam;  Fei Li;  Junrui Li;  Yen-Li Li;  Yang Li;  Xi Liu;  Megan Lo;  Kyle E. Lopez;  Arthur A. Melo;  Frank R. Moss;  Phuong Nguyen;  Joana Paulino;  Komal Ishwar Pawar;  Jessica K. Peters;  Thomas H. Pospiech;  Maliheh Safari;  Smriti Sangwan;  Kaitlin Schaefer;  Paul V. Thomas;  Aye C. Thwin;  Raphael Trenker;  Eric Tse;  Tsz Kin Martin Tsui;  Feng Wang;  Natalie Whitis;  Zanlin Yu;  Kaihua Zhang;  Yang Zhang;  Fengbo Zhou;  Daniel Saltzberg;  QCRG Structural Biology Consortium12†;  Anthony J. Hodder;  Amber S. Shun-Shion;  Daniel M. Williams;  Kris M. White;  Romel Rosales;  Thomas Kehrer;  Lisa Miorin;  Elena Moreno;  Arvind H. Patel;  Suzannah Rihn;  Mir M. Khalid;  Albert Vallejo-Gracia;  Parinaz Fozouni;  Camille R. Simoneau;  Theodore L. Roth;  David Wu;  Mohd Anisul Karim;  Maya Ghoussaini;  Ian Dunham;  Francesco Berardi;  Sebastian Weigang;  Maxime Chazal;  Jisoo Park;  James Logue;  Marisa McGrath;  Stuart Weston;  Robert Haupt;  C. James Hastie;  Matthew Elliott;  Fiona Brown;  Kerry A. Burness;  Elaine Reid;  Mark Dorward;  Clare Johnson;  Stuart G. Wilkinson;  Anna Geyer;  Daniel M. Giesel;  Carla Baillie;  Samantha Raggett;  Hannah Leech;  Rachel Toth;  Nicola Goodman;  Kathleen C. Keough;  Abigail L. Lind;  Zoonomia Consortium‡;  Reyna J. Klesh;  Kafi R. Hemphill;  Jared Carlson-Stevermer;  Jennifer Oki;  Kevin Holden;  Travis Maures;  Katherine S. Pollard;  Andrej Sali;  David A. Agard;  Yifan Cheng;  James S. Fraser;  Adam Frost;  Natalia Jura;  Tanja Kortemme;  Aashish Manglik;  Daniel R. Southworth;  Robert M. Stroud;  Dario R. Alessi;  Paul Davies;  Matthew B. Frieman;  Trey Ideker;  Carmen Abate;  Nolwenn Jouvenet;  Georg Kochs;  Brian Shoichet;  Melanie Ott;  Massimo Palmarini;  Kevan M. Shokat;  Adolfo García-Sastre;  Jeremy A. Rassen;  Robert Grosse;  Oren S. Rosenberg;  Kliment A. Verba;  Christopher F. Basler;  Marco Vignuzzi;  Andrew A. Peden;  Pedro Beltrao;  Nevan J. Krogan
收藏  |  浏览/下载:25/0  |  提交时间:2020/12/07
Tree mode of death and mortality risk factors across Amazon forests 期刊论文
Nature Communications, 2020
作者:  Adriane Esquivel-Muelbert;  Oliver L. Phillips;  Roel J. W. Brienen;  Sophie Fauset;  Martin J. P. Sullivan;  Timothy R. Baker;  Kuo-Jung Chao;  Ted R. Feldpausch;  Emanuel Gloor;  Niro Higuchi;  Jeanne Houwing-Duistermaat;  Jon Lloyd;  Haiyan Liu;  Yadvinder Malhi;  Beatriz Marimon;  Ben Hur Marimon Junior;  Abel Monteagudo-Mendoza;  Lourens Poorter;  Marcos Silveira;  Emilio Vilanova Torre;  Esteban Alvarez Dá;  vila;  Jhon del Aguila Pasquel;  Everton Almeida;  Patricia Alvarez Loayza;  Ana Andrade;  Luiz E. O. C. Aragã;  o;  Alejandro Araujo-Murakami;  Eric Arets;  Luzmila Arroyo;  Gerardo A. Aymard C.;  Michel Baisie;  Christopher Baraloto;  Plí;  nio Barbosa Camargo;  Jorcely Barroso;  Lilian Blanc;  Damien Bonal;  Frans Bongers;  René;  Boot;  Foster Brown;  Benoit Burban;  José;  Luí;  s Camargo;  Wendeson Castro;  Victor Chama Moscoso;  Jerome Chave;  James Comiskey;  Fernando Cornejo Valverde;  Antonio Lola da Costa;  Nallaret Davila Cardozo;  Anthony Di Fiore;  Auré;  lie Dourdain;  Terry Erwin;  Gerardo Flores Llampazo;  Ima Cé;  lia Guimarã;  es Vieira;  Rafael Herrera;  Eurí;  dice Honorio Coronado;  Isau Huamantupa-Chuquimaco;  Eliana Jimenez-Rojas;  Timothy Killeen;  Susan Laurance;  William Laurance;  Aurora Levesley;  Simon L. Lewis;  Karina Liana Lisboa Melgaç;  o Ladvocat;  Gabriela Lopez-Gonzalez;  Thomas Lovejoy;  Patrick Meir;  Casimiro Mendoza;  Paulo Morandi;  David Neill;  Adriano José;  Nogueira Lima;  Percy Nuñ;  ez Vargas;  Edmar Almeida de Oliveira;  Nadir Pallqui Camacho;  Guido Pardo;  Julie Peacock;  Marielos Peñ;  a-Claros;  Maria Cristina Peñ;  uela-Mora;  Georgia Pickavance;  John Pipoly;  Nigel Pitman;  Adriana Prieto;  Thomas A. M. Pugh;  Carlos Quesada;  Hirma Ramirez-Angulo;  Simone Matias de Almeida Reis;  Maxime Rejou-Machain;  Zorayda Restrepo Correa;  Lily Rodriguez Bayona;  Agustí;  n Rudas;  Rafael Salomã;  o;  Julio Serrano;  Javier Silva Espejo;  Natalino Silva;  James Singh;  Clement Stahl;  Juliana Stropp;  Varun Swamy;  Joey Talbot;  Hans ter Steege;  John Terborgh;  Raquel Thomas;  Marisol Toledo;  Armando Torres-Lezama;  Luis Valenzuela Gamarra;  Geertje van der Heijden;  Peter van der Meer;  Peter van der Hout;  Rodolfo Vasquez Martinez;  Simone Aparecida Vieira;  Jeanneth Villalobos Cayo;  Vincent Vos;  Roderick Zagt;  Pieter Zuidema;  David Galbraith
收藏  |  浏览/下载:25/0  |  提交时间:2020/11/20
Set ambitious goals for biodiversity and sustainability 期刊论文
Science, 2020
作者:  Sandra Díaz;  Noelia Zafra-Calvo;  Andy Purvis;  Peter H. Verburg;  David Obura;  Paul Leadley;  Rebecca Chaplin-Kramer;  Luc De Meester;  Ehsan Dulloo;  Berta Martín-López;  M. Rebecca Shaw;  Piero Visconti;  Wendy Broadgate;  Michael W. Bruford;  Neil D. Burgess;  Jeannine Cavender-Bares;  Fabrice DeClerck;  José María Fernández-Palacios;  Lucas A. Garibaldi;  Samantha L. L. Hill;  Forest Isbell;  Colin K. Khoury;  Cornelia B. Krug;  Jianguo Liu;  Martine Maron;  Philip J. K. McGowan;  Henrique M. Pereira;  Victoria Reyes-García;  Juan Rocha;  Carlo Rondinini;  Lynne Shannon;  Yunne-Jai Shin;  Paul V. R. Snelgrove;  Eva M. Spehn;  Bernardo Strassburg;  Suneetha M. Subramanian;  Joshua J. Tewksbury;  James E. M. Watson;  Amy E. Zanne
收藏  |  浏览/下载:22/0  |  提交时间:2020/10/26
Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception 期刊论文
Science, 2020
作者:  Nicole L. Neubarth;  Alan J. Emanuel;  Yin Liu;  Mark W. Springel;  Annie Handler;  Qiyu Zhang;  Brendan P. Lehnert;  Chong Guo;  Lauren L. Orefice;  Amira Abdelaziz;  Michelle M. DeLisle;  Michael Iskols;  Julia Rhyins;  Soo J. Kim;  Stuart J. Cattel;  Wade Regehr;  Christopher D. Harvey;  Jan Drugowitsch;  David D. Ginty
收藏  |  浏览/下载:6/0  |  提交时间:2020/06/22
Protein-structure prediction gets real 期刊论文
NATURE, 2020, 577 (7792) : 627-628
作者:  Pillai, Arvind S.;  Chandler, Shane A.;  Liu, Yang;  Signor, Anthony, V;  Cortez-Romero, Carlos R.;  Benesch, Justin L. P.;  Laganowsky, Arthur;  Storz, Jay F.;  Hochberg, Georg K. A.;  Thornton, Joseph W.
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

Two threads of research in the quest for methods that predict the 3D structures of proteins from their amino-acid sequences have become fully intertwined. The result is a leap forward in the accuracy of predictions.


  
Disruption of emergency response to vulnerable populations during floods 期刊论文
NATURE SUSTAINABILITY, 2020
作者:  Yu, Dapeng;  Yin, Jie;  Wilby, Robert L.;  Lane, Stuart N.;  Aerts, Jeroen C. J. H.;  Lin, Ning;  Liu, Min;  Yuan, Hongyong;  Chen, Jianguo;  Prudhomme, Christel;  Guan, Mingfu;  Baruch, Avinoam;  Johnson, Charlie W. D.;  Tule, Xi;  Yu, Lizhong;  Xu, Shiyuan
收藏  |  浏览/下载:19/0  |  提交时间:2020/05/20
Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation throughS-palmitoylation (vol 573, pg 139, 2019) (Retraction of Vol 573, Pg 139, 2020) 期刊论文
NATURE, 2020, 583 (7814) : 154-154
作者:  Zhang, Hao;  Liu, Chun-Xiao;  Gazibegovic, Sasa;  Xu, Di;  Logan, John A.;  Wang, Guanzhong;  van Loo, Nick;  Bommer, Jouri D. S.;  de Moor, Michiel W. A.;  Car, Diana;  Op Het Veld, Roy L. M.;  van Veldhoven, Petrus J.;  Koelling, Sebastian;  Verheijen, Marcel A.;  Pendharkar, Mihir;  Pennachio, Daniel J.;  Shojaei, Borzoyeh;  Lee, Joon Sue;  Palmstrom, Chris J.;  Bakkers, Erik P. A. M.;  Sarma, S. Das;  Kouwenhoven, Leo P.
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/03
Electrical manipulation of a topological antiferromagnetic state 期刊论文
NATURE, 2020, 580 (7805) : 608-+
作者:  Chabon, Jacob J.;  Hamilton, Emily G.;  Kurtz, David M.;  Esfahani, Mohammad S.;  Moding, Everett J.;  Stehr, Henning;  Schroers-Martin, Joseph;  Nabet, Barzin Y.;  Chen, Binbin;  Chaudhuri, Aadel A.;  Liu, Chih Long;  Hui, Angela B.;  Jin, Michael C.;  Azad, Tej D.;  Almanza, Diego;  Jeon, Young-Jun;  Nesselbush, Monica C.;  Keh, Lyron Co Ting;  Bonilla, Rene F.;  Yoo, Christopher H.;  Ko, Ryan B.;  Chen, Emily L.;  Merriott, David J.;  Massion, Pierre P.;  Mansfield, Aaron S.;  Jen, Jin;  Ren, Hong Z.;  Lin, Steven H.;  Costantino, Christina L.;  Burr, Risa;  Tibshirani, Robert;  Gambhir, Sanjiv S.;  Berry, Gerald J.;  Jensen, Kristin C.;  West, Robert B.;  Neal, Joel W.;  Wakelee, Heather A.;  Loo, Billy W., Jr.;  Kunder, Christian A.;  Leung, Ann N.;  Lui, Natalie S.;  Berry, Mark F.;  Shrager, Joseph B.;  Nair, Viswam S.;  Haber, Daniel A.;  Sequist, Lecia V.;  Alizadeh, Ash A.;  Diehn, Maximilian
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/03

Room-temperature electrical switching of a topological antiferromagnetic state in polycrystalline Mn3Sn thin films is demonstrated using the same protocol as that used for conventional ferromagnetic metals.


Electrical manipulation of phenomena generated by nontrivial band topology is essential for the development of next-generation technology using topological protection. A Weyl semimetal is a three-dimensional gapless system that hosts Weyl fermions as low-energy quasiparticles(1-4). It has various exotic properties, such as a large anomalous Hall effect (AHE) and chiral anomaly, which are robust owing to the topologically protected Weyl nodes(1-16). To manipulate such phenomena, a magnetic version of Weyl semimetals would be useful for controlling the locations of Weyl nodes in the Brillouin zone. Moreover, electrical manipulation of antiferromagnetic Weyl metals would facilitate the use of antiferromagnetic spintronics to realize high-density devices with ultrafast operation(17,18). However, electrical control of a Weyl metal has not yet been reported. Here we demonstrate the electrical switching of a topological antiferromagnetic state and its detection by the AHE at room temperature in a polycrystalline thin film(19) of the antiferromagnetic Weyl metal Mn3Sn9,10,12,20, which exhibits zero-field AHE. Using bilayer devices composed of Mn3Sn and nonmagnetic metals, we find that an electrical current density of about 10(10) to 10(11) amperes per square metre induces magnetic switching in the nonmagnetic metals, with a large change in Hall voltage. In addition, the current polarity along the bias field and the sign of the spin Hall angle of the nonmagnetic metals-positive for Pt (ref. (21)), close to 0 for Cu and negative for W (ref. (22))-determines the sign of the Hall voltage. Notably, the electrical switching in the antiferromagnet is achieved with the same protocol as that used for ferromagnetic metals(23,24). Our results may lead to further scientific and technological advances in topological magnetism and antiferromagnetic spintronics.