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Large variations in volcanic aerosol forcing efficiency due to eruption source parameters and rapid adjustments 期刊论文
Geophysical Research Letters, 2020
作者:  Lauren R. Marshall;  Christopher J. Smith;  Piers M. Forster;  Thomas J. Aubry;  Timothy Andrews;  Anja Schmidt
收藏  |  浏览/下载:7/0  |  提交时间:2020/09/22
Publisher Correction: Current and future global climate impacts resulting from COVID-19 期刊论文
Nature, 2020
作者:  Piers M. Forster;  Harriet I. Forster;  Mat J. Evans;  Matthew J. Gidden;  Chris D. Jones;  Christoph A. Keller;  Robin D. Lamboll;  Corinne Le Qué;  ;  Joeri Rogelj;  Deborah Rosen;  Carl-Friedrich Schleussner;  Thomas B. Richardson;  Christopher J. Smith;  Steven T. Turnock
收藏  |  浏览/下载:14/0  |  提交时间:2020/08/18
Current and future global climate impacts resulting from COVID-19 期刊论文
Nature, 2020
作者:  Piers M. Forster;  Harriet I. Forster;  Mat J. Evans;  Matthew J. Gidden;  Chris D. Jones;  Christoph A. Keller;  Robin D. Lamboll;  Corinne Le Qué;  ;  Joeri Rogelj;  Deborah Rosen;  Carl-Friedrich Schleussner;  Thomas B. Richardson;  Christopher J. Smith;  Steven T. Turnock
收藏  |  浏览/下载:13/0  |  提交时间:2020/08/18
Current and future global climate impacts resulting from COVID-19 科技报告
来源:Climate Analytics. 出版年: 2020
作者:  Piers M. Forster;  Harriet I. Forster;  Mat J. Evans;  Matthew J. Gidden;  Chris D. Jones;  Christoph A. Keller;  Robin D. Lamboll;  Corinne Le Quéré;  Joeri Rogelj;  Deborah Rosen;  Carl-Friedrich Schleussner;  Thomas B. Richardson;  Christopher J. Smith;  Steven T. Turnock
收藏  |  浏览/下载:10/0  |  提交时间:2020/08/18
Sensitivity of Historical Climate Simulations to Uncertain Aerosol Forcing 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (13)
作者:  Dittus, Andrea J.;  Hawkins, Ed;  Wilcox, Laura J.;  Sutton, Rowan T.;  Smith, Christopher J.;  Andrews, Martin B.;  Forster, Piers M.
收藏  |  浏览/下载:7/0  |  提交时间:2020/05/25
historical aerosol forcing  climate model simulations  Forcing uncertainty  Transient Climate Response  Large ensemble  
The mutational landscape of normal human endometrial epithelium 期刊论文
NATURE, 2020, 580 (7805) : 640-+
作者:  Rogelj, Joeri;  Forster, Piers M.;  Kriegler, Elmar;  Smith, Christopher J.;  Seferian, Roland
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

All normal somatic cells are thought to acquire mutations, but understanding of the rates, patterns, causes and consequences of somatic mutations in normal cells is limited. The uterine endometrium adopts multiple physiological states over a lifetime and is lined by a gland-forming epithelium(1,2). Here, using whole-genome sequencing, we show that normal human endometrial glands are clonal cell populations with total mutation burdens that increase at about 29 base substitutions per year and that are many-fold lower than those of endometrial cancers. Normal endometrial glands frequently carry '  driver'  mutations in cancer genes, the burden of which increases with age and decreases with parity. Cell clones with drivers often originate during the first decades of life and subsequently progressively colonize the epithelial lining of the endometrium. Our results show that mutational landscapes differ markedly between normal tissues-perhaps shaped by differences in their structure and physiology-and indicate that the procession of neoplastic change that leads to endometrial cancer is initiated early in life.


Whole-genome sequencing of normal human endometrial glands shows that most are clonal cell populations and frequently carry cancer driver mutations that occur early in life, and that parity has a protective effect.


  
New Generation of Climate Models Track Recent Unprecedented Changes in Earth's Radiation Budget Observed by CERES 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (5)
作者:  Loeb, Norman G.;  Wang, Hailan;  Allan, Richard P.;  Andrews, Timothy;  Armour, Kyle;  Cole, Jason N. S.;  Dufresne, Jean-Louis;  Forster, Piers;  Gettelman, Andrew;  Guo, Huan;  Mauritsen, Thorsten;  Ming, Yi;  Paynter, David;  Proistosescu, Cristian;  Stuecker, Malte F.;  Willen, Ulrika;  Wyser, Klaus
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/02
Observational constraints on the effective climate sensitivity from the historical period 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (3)
作者:  Tokarska, Katarzyna B.;  Hegerl, Gabriele C.;  Schurer, Andrew P.;  Forster, Piers M.;  Marvel, Kate
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/02
climate sensitivity  detection and attribution  historical period  greenhouse gases  
Energy budget constraints on historical radiative forcing 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (4) : 313-+
作者:  Andrews, Timothy;  Forster, Piers M.
收藏  |  浏览/下载:6/0  |  提交时间:2020/05/13
A topography of climate change research 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (2) : 118-+
作者:  Callaghan, Max W.;  Minx, Jan C.;  Forster, Piers M.
收藏  |  浏览/下载:6/0  |  提交时间:2020/05/13