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Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity 期刊论文
Science, 2021
作者:  Parsa Akbari;  Ankit Gilani;  Olukayode Sosina;  Jack A. Kosmicki;  Lori Khrimian;  Yi-Ya Fang;  Trikaldarshi Persaud;  Victor Garcia;  Dylan Sun;  Alexander Li;  Joelle Mbatchou;  Adam E. Locke;  Christian Benner;  Niek Verweij;  Nan Lin;  Sakib Hossain;  Kevin Agostinucci;  Jonathan V. Pascale;  Ercument Dirice;  Michael Dunn;  Regeneron Genetics Center‡;  DiscovEHR Collaboration‡;  William E. Kraus;  Svati H. Shah;  Yii-Der I. Chen;  Jerome I. Rotter;  Daniel J. Rader;  Olle Melander;  Christopher D. Still;  Tooraj Mirshahi;  David J. Carey;  Jaime Berumen-Campos;  Pablo Kuri-Morales;  Jesus Alegre-Díaz;  Jason M. Torres;  Jonathan R. Emberson;  Rory Collins;  Suganthi Balasubramanian;  Alicia Hawes;  Marcus Jones;  Brian Zambrowicz;  Andrew J. Murphy;  Charles Paulding;  Giovanni Coppola;  John D. Overton;  Jeffrey G. Reid;  Alan R. Shuldiner;  Michael Cantor;  Hyun M. Kang;  Goncalo R. Abecasis;  Katia Karalis;  Aris N. Economides;  Jonathan Marchini;  George D. Yancopoulos;  Mark W. Sleeman;  Judith Altarejos;  Giusy Della Gatta;  Roberto Tapia-Conyer;  Michal L. Schwartzman;  Aris Baras;  Manuel A. R. Ferreira;  Luca A. Lotta
收藏  |  浏览/下载：26/0  |  提交时间：2021/07/27
Targeting a neoantigen derived from a common TP53 mutation 期刊论文
Science, 2021
作者:  Emily Han-Chung Hsiue;  Katharine M. Wright;  Jacqueline Douglass;  Michael S. Hwang;  Brian J. Mog;  Alexander H. Pearlman;  Suman Paul;  Sarah R. DiNapoli;  Maximilian F. Konig;  Qing Wang;  Annika Schaefer;  Michelle S. Miller;  Andrew D. Skora;  P. Aitana Azurmendi;  Michael B. Murphy;  Qiang Liu;  Evangeline Watson;  Yana Li;  Drew M. Pardoll;  Chetan Bettegowda;  Nickolas Papadopoulos;  Kenneth W. Kinzler;  Bert Vogelstein;  Sandra B. Gabelli;  Shibin Zhou
收藏  |  浏览/下载：9/0  |  提交时间：2021/03/12
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver 期刊论文
Science, 2021
作者:  Fotios Sampaziotis;  Daniele Muraro;  Olivia C. Tysoe;  Stephen Sawiak;  Timothy E. Beach;  Edmund M. Godfrey;  Sara S. Upponi;  Teresa Brevini;  Brandon T. Wesley;  Jose Garcia-Bernardo;  Krishnaa Mahbubani;  Giovanni Canu;  Richard Gieseck;  Natalie L. Berntsen;  Victoria L. Mulcahy;  Keziah Crick;  Corrina Fear;  Sharayne Robinson;  Lisa Swift;  Laure Gambardella;  Johannes Bargehr;  Daniel Ortmann;  Stephanie E. Brown;  Anna Osnato;  Michael P. Murphy;  Gareth Corbett;  William T. H. Gelson;  George F. Mells;  Peter Humphreys;  Susan E. Davies;  Irum Amin;  Paul Gibbs;  Sanjay Sinha;  Sarah A. Teichmann;  Andrew J. Butler;  Teik Choon See;  Espen Melum;  Christopher J. E. Watson;  Kourosh Saeb-Parsy;  Ludovic Vallier
收藏  |  浏览/下载：15/0  |  提交时间：2021/02/22
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth 期刊论文
Science, 2021
作者:  Ryan S. Roark;  Hui Li;  Wilton B. Williams;  Hema Chug;  Rosemarie D. Mason;  Jason Gorman;  Shuyi Wang;  Fang-Hua Lee;  Juliette Rando;  Mattia Bonsignori;  Kwan-Ki Hwang;  Kevin O. Saunders;  Kevin Wiehe;  M. Anthony Moody;  Peter T. Hraber;  Kshitij Wagh;  Elena E. Giorgi;  Ronnie M. Russell;  Frederic Bibollet-Ruche;  Weimin Liu;  Jesse Connell;  Andrew G. Smith;  Julia DeVoto;  Alexander I. Murphy;  Jessica Smith;  Wenge Ding;  Chengyan Zhao;  Neha Chohan;  Maho Okumura;  Christina Rosario;  Yu Ding;  Emily Lindemuth;  Anya M. Bauer;  Katharine J. Bar;  David Ambrozak;  Cara W. Chao;  Gwo-Yu Chuang;  Hui Geng;  Bob C. Lin;  Mark K. Louder;  Richard Nguyen;  Baoshan Zhang;  Mark G. Lewis;  Donald D. Raymond;  Nicole A. Doria-Rose;  Chaim A. Schramm;  Daniel C. Douek;  Mario Roederer;  Thomas B. Kepler;  Garnett Kelsoe;  John R. Mascola;  Peter D. Kwong;  Bette T. Korber;  Stephen C. Harrison;  Barton F. Haynes;  Beatrice H. Hahn;  George M. Shaw
收藏  |  浏览/下载：20/0  |  提交时间：2021/01/15
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters 期刊论文
Science, 2020
作者:  Alina Baum;  Dharani Ajithdoss;  Richard Copin;  Anbo Zhou;  Kathryn Lanza;  Nicole Negron;  Min Ni;  Yi Wei;  Kusha Mohammadi;  Bret Musser;  Gurinder S. Atwal;  Adelekan Oyejide;  Yenny Goez-Gazi;  John Dutton;  Elizabeth Clemmons;  Hilary M. Staples;  Carmen Bartley;  Benjamin Klaffke;  Kendra Alfson;  Michal Gazi;  Olga Gonzalez;  Edward Dick;  Ricardo Carrion;  Laurent Pessaint;  Maciel Porto;  Anthony Cook;  Renita Brown;  Vaneesha Ali;  Jack Greenhouse;  Tammy Taylor;  Hanne Andersen;  Mark G. Lewis;  Neil Stahl;  Andrew J. Murphy;  George D. Yancopoulos;  Christos A. Kyratsous
收藏  |  浏览/下载：13/0  |  提交时间：2020/11/30
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail 期刊论文
Science, 2020
作者:  Johanna Hansen;  Alina Baum;  Kristen E. Pascal;  Vincenzo Russo;  Stephanie Giordano;  Elzbieta Wloga;  Benjamin O. Fulton;  Ying Yan;  Katrina Koon;  Krunal Patel;  Kyung Min Chung;  Aynur Hermann;  Erica Ullman;  Jonathan Cruz;  Ashique Rafique;  Tammy Huang;  Jeanette Fairhurst;  Christen Libertiny;  Marine Malbec;  Wen-yi Lee;  Richard Welsh;  Glen Farr;  Seth Pennington;  Dipali Deshpande;  Jemmie Cheng;  Anke Watty;  Pascal Bouffard;  Robert Babb;  Natasha Levenkova;  Calvin Chen;  Bojie Zhang;  Annabel Romero Hernandez;  Kei Saotome;  Yi Zhou;  Matthew Franklin;  Sumathi Sivapalasingam;  David Chien Lye;  Stuart Weston;  James Logue;  Robert Haupt;  Matthew Frieman;  Gang Chen;  William Olson;  Andrew J. Murphy;  Neil Stahl;  George D. Yancopoulos;  Christos A. Kyratsous
收藏  |  浏览/下载：14/0  |  提交时间：2020/08/25
Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies 期刊论文
Science, 2020
作者:  Alina Baum;  Benjamin O. Fulton;  Elzbieta Wloga;  Richard Copin;  Kristen E. Pascal;  Vincenzo Russo;  Stephanie Giordano;  Kathryn Lanza;  Nicole Negron;  Min Ni;  Yi Wei;  Gurinder S. Atwal;  Andrew J. Murphy;  Neil Stahl;  George D. Yancopoulos;  Christos A. Kyratsous
收藏  |  浏览/下载：7/0  |  提交时间：2020/08/25