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X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease 期刊论文
Science, 2021
作者:  Sebastian Günther;  Patrick Y. A. Reinke;  Yaiza Fernández-García;  Julia Lieske;  Thomas J. Lane;  Helen M. Ginn;  Faisal H. M. Koua;  Christiane Ehrt;  Wiebke Ewert;  Dominik Oberthuer;  Oleksandr Yefanov;  Susanne Meier;  Kristina Lorenzen;  Boris Krichel;  Janine-Denise Kopicki;  Luca Gelisio;  Wolfgang Brehm;  Ilona Dunkel;  Brandon Seychell;  Henry Gieseler;  Brenna Norton-Baker;  Beatriz Escudero-Pérez;  Martin Domaracky;  Sofiane Saouane;  Alexandra Tolstikova;  Thomas A. White;  Anna Hänle;  Michael Groessler;  Holger Fleckenstein;  Fabian Trost;  Marina Galchenkova;  Yaroslav Gevorkov;  Chufeng Li;  Salah Awel;  Ariana Peck;  Miriam Barthelmess;  Frank Schlünzen;  P. Lourdu Xavier;  Nadine Werner;  Hina Andaleeb;  Najeeb Ullah;  Sven Falke;  Vasundara Srinivasan;  Bruno Alves França;  Martin Schwinzer;  Hévila Brognaro;  Cromarte Rogers;  Diogo Melo;  Joanna J. Zaitseva-Doyle;  Juraj Knoska;  Gisel E. Peña-Murillo;  Aida Rahmani Mashhour;  Vincent Hennicke;  Pontus Fischer;  Johanna Hakanpää;  Jan Meyer;  Philip Gribbon;  Bernhard Ellinger;  Maria Kuzikov;  Markus Wolf;  Andrea R. Beccari;  Gleb Bourenkov;  David von Stetten;  Guillaume Pompidor;  Isabel Bento;  Saravanan Panneerselvam;  Ivars Karpics;  Thomas R. Schneider;  Maria Marta Garcia-Alai;  Stephan Niebling;  Christian Günther;  Christina Schmidt;  Robin Schubert;  Huijong Han;  Juliane Boger;  Diana C. F. Monteiro;  Linlin Zhang;  Xinyuanyuan Sun;  Jonathan Pletzer-Zelgert;  Jan Wollenhaupt;  Christian G. Feiler;  Manfred S. Weiss;  Eike-Christian Schulz;  Pedram Mehrabi;  Katarina Karničar;  Aleksandra Usenik;  Jure Loboda;  Henning Tidow;  Ashwin Chari;  Rolf Hilgenfeld;  Charlotte Uetrecht;  Russell Cox;  Andrea Zaliani;  Tobias Beck;  Matthias Rarey;  Stephan Günther;  Dusan Turk;  Winfried Hinrichs;  Henry N. Chapman;  Arwen R. Pearson;  Christian Betzel;  Alke Meents
收藏  |  浏览/下载：14/0  |  提交时间：2021/05/14
Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments 期刊论文
Science, 2021
作者:  Benjamin Vernot;  Elena I. Zavala;  Asier Gómez-Olivencia;  Zenobia Jacobs;  Viviane Slon;  Fabrizio Mafessoni;  Frédéric Romagné;  Alice Pearson;  Martin Petr;  Nohemi Sala;  Adrián Pablos;  Arantza Aranburu;  José María Bermúdez de Castro;  Eudald Carbonell;  Bo Li;  Maciej T. Krajcarz;  Andrey I. Krivoshapkin;  Kseniya A. Kolobova;  Maxim B. Kozlikin;  Michael V. Shunkov;  Anatoly P. Derevianko;  Bence Viola;  Steffi Grote;  Elena Essel;  David López Herráez;  Sarah Nagel;  Birgit Nickel;  Julia Richter;  Anna Schmidt;  Benjamin Peter;  Janet Kelso;  Richard G. Roberts;  Juan-Luis Arsuaga;  Matthias Meyer
收藏  |  浏览/下载：16/0  |  提交时间：2021/05/14
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape 期刊论文
Science, 2021
作者:  Paul-Albert Koenig;  Hrishikesh Das;  Hejun Liu;  Beate M. Kümmerer;  Florian N. Gohr;  Lea-Marie Jenster;  Lisa D. J. Schiffelers;  Yonas M. Tesfamariam;  Miki Uchima;  Jennifer D. Wuerth;  Karl Gatterdam;  Natalia Ruetalo;  Maria H. Christensen;  Caroline I. Fandrey;  Sabine Normann;  Jan M. P. Tödtmann;  Steffen Pritzl;  Leo Hanke;  Jannik Boos;  Meng Yuan;  Xueyong Zhu;  Jonathan L. Schmid-Burgk;  Hiroki Kato;  Michael Schindler;  Ian A. Wilson;  Matthias Geyer;  Kerstin U. Ludwig;  B. Martin Hällberg;  Nicholas C. Wu;  Florian I. Schmidt
收藏  |  浏览/下载：20/0  |  提交时间：2021/02/17
Capturing roaming molecular fragments in real time 期刊论文
Science, 2020
作者:  Tomoyuki Endo;  Simon P. Neville;  Vincent Wanie;  Samuel Beaulieu;  Chen Qu;  Jude Deschamps;  Philippe Lassonde;  Bruno E. Schmidt;  Hikaru Fujise;  Mizuho Fushitani;  Akiyoshi Hishikawa;  Paul L. Houston;  Joel M. Bowman;  Michael S. Schuurman;  François Légaré;  Heide Ibrahim
收藏  |  浏览/下载：9/0  |  提交时间：2020/11/30
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells 期刊论文
Science, 2020
作者:  Kyle K. Payne;  Jessica A. Mine;  Subir Biswas;  Ricardo A. Chaurio;  Alfredo Perales-Puchalt;  Carmen M. Anadon;  Tara Lee Costich;  Carly M. Harro;  Jennifer Walrath;  Qianqian Ming;  Evgenii Tcyganov;  Andrea L. Buras;  Kristen E. Rigolizzo;  Gunjan Mandal;  Jason Lajoie;  Michael Ophir;  Julia Tchou;  Douglas Marchion;  Vincent C. Luca;  Piotr Bobrowicz;  Brooke McLaughlin;  Ugur Eskiocak;  Michael Schmidt;  Juan R. Cubillos-Ruiz;  Paulo C. Rodriguez;  Dmitry I. Gabrilovich;  Jose R. Conejo-Garcia
收藏  |  浏览/下载：10/0  |  提交时间：2020/08/25
SARS-CoV-2 infection protects against rechallenge in rhesus macaques 期刊论文
Science, 2020
作者:  Abishek Chandrashekar;  Jinyan Liu;  Amanda J. Martinot;  Katherine McMahan;  Noe B. Mercado;  Lauren Peter;  Lisa H. Tostanoski;  Jingyou Yu;  Zoltan Maliga;  Michael Nekorchuk;  Kathleen Busman-Sahay;  Margaret Terry;  Linda M. Wrijil;  Sarah Ducat;  David R. Martinez;  Caroline Atyeo;  Stephanie Fischinger;  John S. Burke;  Matthew D. Slein;  Laurent Pessaint;  Alex Van Ry;  Jack Greenhouse;  Tammy Taylor;  Kelvin Blade;  Anthony Cook;  Brad Finneyfrock;  Renita Brown;  Elyse Teow;  Jason Velasco;  Roland Zahn;  Frank Wegmann;  Peter Abbink;  Esther A. Bondzie;  Gabriel Dagotto;  Makda S. Gebre;  Xuan He;  Catherine Jacob-Dolan;  Nicole Kordana;  Zhenfeng Li;  Michelle A. Lifton;  Shant H. Mahrokhian;  Lori F. Maxfield;  Ramya Nityanandam;  Joseph P. Nkolola;  Aaron G. Schmidt;  Andrew D. Miller;  Ralph S. Baric;  Galit Alter;  Peter K. Sorger;  Jacob D. Estes;  Hanne Andersen;  Mark G. Lewis;  Dan H. Barouch
收藏  |  浏览/下载：10/0  |  提交时间：2020/08/18