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A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage (vol 551, pg 629, 2017) 期刊论文
NATURE, 2020, 580 (7802) : E5-E5
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/03
Nightside condensation of iron in an ultrahot giant exoplanet 期刊论文
NATURE, 2020, 580 (7805) : 597-+
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载：63/0  |  提交时间：2020/07/03

Ultrahot giant exoplanets receive thousands of times Earth'  s insolation(1,2). Their high-temperature atmospheres (greater than 2,000 kelvin) are ideal laboratories for studying extreme planetary climates and chemistry(3-5). Daysides are predicted to be cloud-free, dominated by atomic species(6) and much hotter than nightsides(5,7,8). Atoms are expected to recombine into molecules over the nightside(9), resulting in different day and night chemistries. Although metallic elements and a large temperature contrast have been observed(10-14), no chemical gradient has been measured across the surface of such an exoplanet. Different atmospheric chemistry between the day-to-night ('  evening'  ) and night-to-day ('  morning'  ) terminators could, however, be revealed as an asymmetric absorption signature during transit(4,7,15). Here we report the detection of an asymmetric atmospheric signature in the ultrahot exoplanet WASP-76b. We spectrally and temporally resolve this signature using a combination of high-dispersion spectroscopy with a large photon-collecting area. The absorption signal, attributed to neutral iron, is blueshifted by -11 +/- 0.7 kilometres per second on the trailing limb, which can be explained by a combination of planetary rotation and wind blowing from the hot dayside(16). In contrast, no signal arises from the nightside close to the morning terminator, showing that atomic iron is not absorbing starlight there. We conclude that iron must therefore condense during its journey across the nightside.


Absorption lines of iron in the dayside atmosphere of an ultrahot giant exoplanet disappear after travelling across the nightside, showing that the iron has condensed during its travel.


  
Spatio-temporally Resolved Methane Fluxes From the Los Angeles Megacity 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (9) : 5131-5148
作者:  Yadav, Vineet;  Duren, Riley;  Mueller, Kim;  Verhulst, Kristal R.;  Nehrkorn, Thomas;  Kim, Jooil;  Weiss, Ray F.;  Keeling, Ralph;  Sander, Stanley;  Fischer, Marc L.;  Newman, Sally;  Falk, Matthias;  Kuwayama, Toshihiro;  Hopkins, Francesca;  Rafiq, Talha;  Whetstone, James;  Miller, Charles
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/26
High-fructose corn syrup enhances intestinal tumor growth in mice 期刊论文
SCIENCE, 2019, 363 (6433) : 1345-+
作者:  Goncalves, Marcus D.;  Lu, Changyuan;  Tutnauer, Jordan;  Hartman, Travis E.;  Hwang, Seo-Kyoung;  Murphy, Charles J.;  Pauli, Chantal;  Morris, Roxanne;  Taylor, Sam;  Bosch, Kaitlyn;  Yang, Sukjin;  Wang, Yumei;  Van Riper, Justin;  Lekaye, H. Carl;  Roper, Jatin;  Kim, Young;  Chen, Qiuying;  Gross, Steven S.;  Rhee, Kyu Y.;  Cantley, Lewis C.;  Yun, Jihye
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
An isotopically distinct Zealandia-Antarctic mantle domain in the Southern Ocean 期刊论文
NATURE GEOSCIENCE, 2019, 12 (3) : 206-+
作者:  Park, Sung-Hyun;  Langmuir, Charles H.;  Sims, Kenneth W. W.;  Blichert-Toft, Janne;  Kim, Seung-Sep;  Scott, Sean R.;  Lin, Jian;  Choi, Hakkyum;  Yang, Yun-Seok;  Michael, Peter J.
收藏  |  浏览/下载：12/0  |  提交时间：2019/04/09
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity (vol 483, pg 603, 2012) 期刊论文
NATURE, 2019, 565 (7738) : E5-E6
作者:  Barretina, Jordi;  Caponigro, Giordano;  Stransky, Nicolas;  Venkatesan, Kavitha;  Margolin, Adam A.;  Kim, Sungjoon;  Wilson, Christopher J.;  Lehar, Joseph;  Kryukov, Gregory V.;  Sonkin, Dmitriy;  Reddy, Anupama;  Liu, Manway;  Murray, Lauren;  Berger, Michael F.;  Monahan, John E.;  Morais, Paula;  Meltzer, Jodi;  Korejwa, Adam;  Jane-Valbuena, Judit;  Mapa, Felipa A.;  Thibault, Joseph;  Bric-Furlong, Eva;  Raman, Pichai;  Shipway, Aaron;  Engels, Ingo H.;  Cheng, Jill;  Yu, Guoying K.;  Yu, Jianjun;  Aspesi, Peter, Jr.;  de Silva, Melanie;  Jagtap, Kalpana;  Jones, Michael D.;  Wang, Li;  Hatton, Charles;  Palescandolo, Emanuele;  Gupta, Supriya;  Mahan, Scott;  Sougnez, Carrie;  Onofrio, Robert C.;  Liefeld, Ted;  MacConaill, Laura;  Winckler, Wendy;  Reich, Michael;  Li, Nanxin;  Mesirov, Jill P.;  Gabriel, Stacey B.;  Getz, Gad;  Ardlie, Kristin;  Chan, Vivien;  Myer, Vic E.;  Weber, Barbara L.;  Porter, Jeff;  Warmuth, Markus;  Finan, Peter;  Harris, Jennifer L.;  Meyerson, Matthew;  Golub, Todd R.;  Morrissey, Michael P.;  Sellers, William R.;  Schlegel, Robert;  Garraway, Levi A.
收藏  |  浏览/下载：23/0  |  提交时间：2019/11/27
New NSF policy will stifle innovation 期刊论文
SCIENCE, 2018, 362 (6412) : 297-298
作者:  Alberts, Susan;  Anderson, Rindy;  Ballen, Cissy J.;  Barrick, Jeffrey E.;  Bordenstein, Seth;  Boyd, Sunny K.;  Bracken-Grissom, Heather;  Braun, Christopher B.;  Coppola, David M.;  Cox, Daniel N.;  Crandall, Keith A.;  Cronin, Thomas W.;  Demas, Gregory E.;  Derby, Charles D.;  Edwards, Scott V.;  Eisthen, Heather L.;  Foster, James A.;  Gilbert, Cole;  Halanych, Kenneth M.;  Herculano-Houzel, Suzana;  Hoekstra, Hopi;  Hof, Patrick R.;  Hoke, Kim L.;  Holekamp, Kay E.;  Jarvis, Erich;  Johnsen, Sonke;  Katz, Paul S.;  Kay, Leslie M.;  Kehoe, David M.;  Kelley, Darcy B.;  Kerr, Benjamin;  Ketterson, Ellen;  Kier, William M.;  Koehl, Mimi A. R.;  Last, Robert L.;  Lazazzera, Beth;  Lenski, Richard E.;  Losos, Jonathan B.;  Lutterschmidt, Deborah I.;  Lynch, Michael;  Mahon, Andrew R.;  Martindale, Mark Q.;  Martins, Emilia P.;  McClintock, James B.;  Mesce, Karen A.;  Mukhopadhyay, Suchetana;  Oakley, Todd H.;  Phelps, Steven M.;  Phillips, Richard P.;  Queller, David;  Renn, Suzy C. P.;  Rosvall, Kimberly;  Schweizer, Felix E.;  Shubin, Neil;  Silk, Joan;  Strassmann, Joan E.;  Strausfeld, Nicholas J.;  Strauss, Sharon Y.;  Striedter, Georg;  Swalla, Billie J.;  Tarrant, Ann;  Throop, Heather L.;  Turner, Paul E.;  Voss, S. Randal;  Wake, Marvalee H.;  Wares, John P.;  Webster, Mike;  White, Stephanie A.;  Wilczynski, Walter;  Wray, Greg A.;  Wright, Timothy F.
收藏  |  浏览/下载：21/0  |  提交时间：2019/11/27
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma 期刊论文
SCIENCE, 2018, 361 (6399) : 290-295
作者:  Zhang, Jing;  Wu, Tao;  Simon, Jeremy;  Takada, Mamoru;  Saito, Ryoichi;  Fan, Cheng;  Liu, Xian-De;  Jonasch, Eric;  Xie, Ling;  Chen, Xian;  Yao, Xiaosai;  Teh, Bin Tean;  Tan, Patrick;  Zheng, Xingnan;  Li, Mingjie;  Lawrence, Cortney;  Fan, Jie;  Geng, Jiang;  Liu, Xijuan;  Hu, Lianxin;  Wang, Jun;  Liao, Chengheng;  Hong, Kai;  Zurlo, Giada;  Parker, Joel S.;  Auman, J. Todd;  Perou, Charles M.;  Rathmell, W. Kimryn;  Kim, William Y.;  Kirschner, Marc W.;  Kaelin, William G., Jr.;  Baldwin, Albert S.;  Zhang, Qing
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/27
Dentate gyrus mossy cells control spontaneous convulsive seizures and spatial memory 期刊论文
SCIENCE, 2018, 359 (6377) : 787-790
作者:  Bui, Anh D.;  Nguyen, Theresa M.;  Limouse, Charles;  Kim, Hannah K.;  Szabo, Gergely G.;  Felong, Sylwia;  Maroso, Mattia;  Soltesz, Ivan
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27
Carbon dioxide and methane measurements from the Los Angeles Megacity Carbon Project - Part 1: calibration, urban enhancements, and uncertainty estimates 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2017, 17 (13)
作者:  Verhulst, Kristal R.;  Karion, Anna;  Kim, Jooil;  Salameh, Peter K.;  Keeling, Ralph F.;  Newman, Sally;  Miller, John;  Sloop, Christopher;  Pongetti, Thomas;  Rao, Preeti;  Wong, Clare;  Hopkins, Francesca M.;  Yadav, Vineet;  Weiss, Ray F.;  Duren, Riley M.;  Miller, Charles E.
收藏  |  浏览/下载：18/0  |  提交时间：2019/04/09