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Cluster Observations on Time-of-Flight Effect of Oxygen Ions in Magnetotail Reconnection Exhaust Region 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (3)
作者:  Wu, T.;  Fu, S. Y.;  Xie, L.;  Zong, Q-G;  Zhou, X. Z.;  Yue, C.;  Sun, W. J.;  Pu, Z. Y.;  Xiong, Y.;  Zhao, S. J.;  Zhang, H.;  Yu, F. B.
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/02
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Rossby Waves Detection in the CO2 and Temperature Multilayer Climate Network 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (2)
作者:  Ying, N.;  Zhou, D.;  Han, Z. G.;  Chen, Q. H.;  Ye, Q.;  Xue, Z. G.
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/02
mid-troposphere CO2 concentrations  surface air temperature  multilayer climate network  Rossby waves  
Direct Evidence for Electron Acceleration Within Ion-Scale Flux Rope 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (1)
作者:  Zhong, Z. H.;  Zhou, M.;  Tang, R. X.;  Deng, X. H.;  Turner, D. L.;  Cohen, I. J.;  Pang, Y.;  Man, H. Y.;  Russell, C. T.;  Giles, B.;  Paterson, W. R.;  Khotyaintsev, Y.;  Burch, J. L.
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/02
Features of the Deep Atmospheric Boundary Layer Over the Taklimakan Desert in the Summertime and its Influence on Regional Circulation 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (23) : 12755-12772
作者:  Wang, Minzhong;  Xu, Xiangde;  Xu, Hongxiong;  Lenschow, Donald H.;  Zhou, Mingyu;  Zhang, Jiantao;  Wang, Yinjun
收藏  |  浏览/下载:7/0  |  提交时间:2020/02/17
Predominance of secondary organic aerosol to particle-bound reactive oxygen species activity in fine ambient aerosol 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (23) : 14703-14720
作者:  Zhou, Jun;  Elser, Miriam;  Huang, Ru-Jin;  Krapf, Manuel;  Frohlich, Roman;  Bhattu, Deepika;  Stefenelli, Giulia;  Zotter, Peter;  Bruns, Emily A.;  Pieber, Simone M.;  Ni, Haiyan;  Wang, Qiyuan;  Wang, Yichen;  Zhou, Yaqing;  Chen, Chunying;  Xiao, Mao;  Slowik, Jay G.;  Brown, Samuel;  Cassagnes, Laure-Estelle;  Daellenbach, Kaspar R.;  Nussbaumer, Thomas;  Geiser, Marianne;  Prevot, Andre S. H.;  El-Haddad, Imad;  Cao, Junji;  Baltensperger, Urs;  Dommen, Josef
收藏  |  浏览/下载:7/0  |  提交时间:2020/02/17
Multi-model analysis of climate impacts on plant photosynthesis in China during 2000-2015 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2019, 39 (15) : 5539-5555
作者:  Yan, Hao;  Wang, Shao-Qiang;  Cao, Yun;  Xu, Ling-Ling;  Wu, Men-xin;  Cheng, Lu;  Mao, Liu-Xi;  Zhang, Xian-Zhou;  Liu, Yun-Fen;  Wang, Yan-Fen;  Chen, Shi-Ping;  Li, Ying-Nian;  Han, Shi-Jie;  Zhou, Guo-Yi;  Zhang, Yi-Ping;  Shugart, Herman H.;  Wang, Jun-Bang;  Zhao, Feng-Hua
收藏  |  浏览/下载:13/0  |  提交时间:2020/02/17
climate change  dry/wet climate  Gross primary production  meteorological factors  multi-model analysis  
Energy Conversion and Dissipation at Dipolarization Fronts: A Statistical Overview 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2019, 46 (22) : 12693-12701
作者:  Zhong, Z. H.;  Deng, X. H.;  Zhou, M.;  Ma, W. Q.;  Tang, R. X.;  Khotyaintsev, Y. V.;  Giles, B. L.;  Russell, C. T.;  Burch, J. L.
收藏  |  浏览/下载:19/0  |  提交时间:2020/02/17
dipolarization front  energy conversion  energy dissipation  
Torsional refrigeration by twisted, coiled, and supercoiled fibers 期刊论文
SCIENCE, 2019, 366 (6462) : 216-+
作者:  Wang, Run;  Fang, Shaoli;  Xiao, Yicheng;  Gao, Enlai;  Jiang, Nan;  Li, Yaowang;  Mou, Linlin;  Shen, Yanan;  Zhao, Wubin;  Li, Sitong;  Fonseca, Alexandre F.;  Galvao, Douglas S.;  Chen, Mengmeng;  He, Wenqian;  Yu, Kaiqing;  Lu, Hongbing;  Wang, Xuemin;  Qian, Dong;  Aliev, Ali E.;  Li, Na;  Haines, Carter S.;  Liu, Zhongsheng;  Mu, Jiuke;  Wang, Zhong;  Yin, Shougen;  Lima, Marcio D.;  An, Baigang;  Zhou, Xiang;  Liu, Zunfeng;  Baughman, Ray H.
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Delayed impacts of the IOD: cross-seasonal relationships between the IOD, Tibetan Plateau snow, and summer precipitation over the Yangtze-Huaihe River region 期刊论文
CLIMATE DYNAMICS, 2019, 53: 4077-4093
作者:  Zhang, Yue;  Zhou, Wen;  Chow, Eric C. H.;  Leung, Marco Y. T.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27