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Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer 期刊论文
SCIENCE, 2017, 358 (6360) : 234-+
作者:  Drost, Jarno;  van Boxtel, Ruben;  Blokzijl, Francis;  Mizutani, Tomohiro;  Sasaki, Nobuo;  Sasselli, Valentina;  de Ligt, Joep;  Behjati, Sam;  Grolleman, Judith E.;  van Wezel, Tom;  Nik-Zainal, Serena;  Kuiper, Roland P.;  Cuppen, Edwin;  Clevers, Hans
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade 期刊论文
SCIENCE, 2017, 357 (6349) : 409-413
作者:  Le, Dung T.;  Durham, Jennifer N.;  Smith, Kellie N.;  Wang, Hao;  Bartlett, Bjarne R.;  Aulakh, Laveet K.;  Lu, Steve;  Kemberling, Holly;  Wilt, Cara;  Luber, Brandon S.;  Wong, Fay;  Azad, Nilofer S.;  Rucki, Agnieszka A.;  Laheru, Dan;  Donehower, Ross;  Zaheer, Atif;  Fisher, George A.;  Crocenzi, Todd S.;  Lee, James J.;  Greten, Tim F.;  Duffy, Austin G.;  Ciombor, Kristen K.;  Eyring, Aleksandra D.;  Lam, Bao H.;  Joe, Andrew;  Kang, S. Peter;  Holdhoff, Matthias;  Danilova, Ludmila;  Cope, Leslie;  Meyer, Christian;  Zhou, Shibin;  Goldberg, Richard M.;  Armstrong, Deborah K.;  Bever, Katherine M.;  Fader, Amanda N.;  Taube, Janis;  Housseau, Franck;  Spetzler, David;  Xiao, Nianqing;  Pardoll, Drew M.;  Papadopoulos, Nickolas;  Kinzler, Kenneth W.;  Eshleman, James R.;  Vogelstein, Bert;  Anders, Robert A.;  Diaz, Luis A., Jr.
收藏  |  浏览/下载:19/0  |  提交时间:2019/11/27
Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells 期刊论文
SCIENCE, 2017, 356 (6337) : 503-+
作者:  Takahashi, Yuta;  Wu, Jun;  Suzuki, Keiichiro;  Martinez-Redondo, Paloma;  Li, Mo;  Liao, Hsin-Kai;  Wu, Min-Zu;  Hernandez-Benitez, Reyna;  Hishida, Tomoaki;  Shokhirev, Maxim Nikolaievich;  Esteban, Concepcion Rodriguez;  Sancho-Martinez, Ignacio;  Belmonte, Juan Carlos Izpisua
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Nucleic acid detection with CRISPR-Cas13a/C2c2 期刊论文
SCIENCE, 2017, 356 (6336) : 438-+
作者:  Gootenberg, Jonathan S.;  Abudayyeh, Omar O.;  Lee, Jeong Wook;  Essletzbichler, Patrick;  Dy, Aaron J.;  Joung, Julia;  Verdine, Vanessa;  Donghia, Nina;  Daringer, Nichole M.;  Freije, Catherine A.;  Myhrvold, Cameron;  Bhattacharyya, Roby P.;  Livny, Jonathan;  Regev, Aviv;  Koonin, Eugene V.;  Hung, Deborah T.;  Sabeti, Pardis C.;  Collins, James J.;  Zhang, Feng
收藏  |  浏览/下载:18/0  |  提交时间:2019/11/27
Scalable-manufactured randomized glass-polymer hybrid metamaterial for daytime radiative cooling 期刊论文
SCIENCE, 2017, 355 (6329)
作者:  Zhai, Yao;  Ma, Yaoguang;  David, Sabrina N.;  Zhao, Dongliang;  Lou, Runnan;  Tan, Gang;  Yang, Ronggui;  Yin, Xiaobo
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport 期刊论文
SCIENCE, 2017, 355 (6327)
作者:  O&;  39;Brien, Elizabeth
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
Cognition-mediated evolution of low-quality floral nectars 期刊论文
SCIENCE, 2017, 355 (6320) : 75-+
作者:  Nachev, Vladislav;  Stich, Kai Petra;  Winter, Clemens;  Bond, Alan;  Kamil, Alan;  Winter, York
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/27