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Astronaut with sights on Mars 期刊论文
NATURE, 2020, 581 (7809) : 367-367
作者:  Funabashi, Masanori;  Grove, Tyler L.;  Wang, Min;  Varma, Yug;  McFadden, Molly E.;  Brown, Laura C.;  Guo, Chunjun;  Higginbottom, Steven;  Almo, Steven C.;  Fischbach, Michael A.
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/03

NASA astronaut Jessica Watkins is at the forefront of a new crop of space explorers destined for the Moon, and maybe one day, Mars.


NASA astronaut Jessica Watkins is at the forefront of a new crop of space explorers destined for the Moon, and maybe one day, Mars.


  
Turning connective tissue into neurons for 10 years 期刊论文
NATURE, 2020, 578 (7796) : 522-524
作者:  Acquaviva, Laurent;  Boekhout, Michiel;  Karasu, Mehmet E.;  Brick, Kevin;  Pratto, Florencia;  Li, Tao;  van Overbeek, Megan;  Kauppi, Liisa;  Camerini-Otero, R. Daniel;  Jasin, Maria;  Keeney, Scott
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/03

An historic breakthrough that altered our understanding of cell fate.


A method for directly converting connective-tissue cells into neurons opened up a new branch of research into cell-based therapies and called into question long-held beliefs about how development affects a cell'  s identity.


  
HELP FOR THE HIGH SEAS 期刊论文
NATURE, 2020, 580 (7801) : 20-22
作者:  Grishin, Evgeni;  Malamud, Uri;  Perets, Hagai B.;  Wandel, Oliver;  Schaefer, Christoph M.
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/03

Several cancer and HIV drugs have come from marine organisms, but scientists worry that a new agreement to save species could hinder some research.


Several cancer and HIV drugs have come from marine organisms, but scientists worry that a new agreement to save species could hinder some research.


  
Check for publication integrity before misconduct 期刊论文
NATURE, 2020, 577 (7789) : 167-169
作者:  Grey, Andrew;  Bolland, Mark J.;  Avenell, Alison;  Klein, Andrew A.;  Gunsalus, C. K.
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/03
New Year's resolution: one meeting-free week a quarter 期刊论文
NATURE, 2020, 577 (7789) : 147-147
作者:  Rehm, Heidi
收藏  |  浏览/下载:0/0  |  提交时间:2020/07/03
Fourth defence molecule completes antiviral line-up 期刊论文
NATURE, 2020, 581 (7808) : 266-267
作者:  Marshall, Michael
收藏  |  浏览/下载:4/0  |  提交时间:2020/07/03

Toll-like receptors can initiate an immune response when they detect signs of a viral or microbial threat. New insight into how such receptor activation drives defence programs should aid our efforts to understand autoimmune diseases.


Key adaptor protein found in a pathway that drives interferon production.


  
Skeleton of a Cretaceous mammal from Madagascar reflects long-term insularity 期刊论文
NATURE, 2020
作者:  Petit, L.;  Eenink, H. G. J.;  Russ, M.;  Lawrie, W. I. L.;  Hendrickx, N. W.;  Philips, S. G. J.;  Clarke, J. S.;  Vandersypen, L. M. K.;  Veldhorst, M.
收藏  |  浏览/下载:9/0  |  提交时间:2020/05/13

The fossil record of mammaliaforms (mammals and their closest relatives) of the Mesozoic era from the southern supercontinent Gondwana is far less extensive than that from its northern counterpart, Laurasia(1,2). Among Mesozoic mammaliaforms, Gondwanatheria is one of the most poorly known clades, previously represented by only a single cranium and isolated jaws and teeth(1-5). As a result, the anatomy, palaeobiology and phylogenetic relationships of gondwanatherians remain unclear. Here we report the discovery of an articulated and very well-preserved skeleton of a gondwanatherian of the latest age (72.1-66 million years ago) of the Cretaceous period from Madagascar that we assign to a new genus and species, Adalatherium hui. To our knowledge, the specimen is the most complete skeleton of a Gondwanan Mesozoic mammaliaform that has been found, and includes the only postcranial material and ascending ramus of the dentary known for any gondwanatherian. A phylogenetic analysis including the new taxon recovers Gondwanatheria as the sister group to Multituberculata. The skeleton, which represents one of the largest of the Gondwanan Mesozoic mammaliaforms, is particularly notable for exhibiting many unique features in combination with features that are convergent on those of therian mammals. This uniqueness is consistent with a lineage history for A. hui of isolation on Madagascar for more than 20 million years.


Adalatherium hui, a newly discovered gondwanatherian mammal from Madagascar dated to near the end of the Cretaceous period, shows features consistent with a long evolutionary trajectory of isolation in an insular environment.


  
THE INHALER MAKEOVER 期刊论文
NATURE, 2020, 581 (7807) : S14-S17
作者:  Baeckens, Simon;  Blomberg, Simone P.;  Shine, Richard
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/03

A ban on CFCs in the 1980s prompted a rethink of the devices used to deliver respiratory drugs, now new worries and the ongoing problems that some patients have using inhalers are bringing change.


A ban on CFCs in the 1980s prompted a rethink of the devices used to deliver respiratory drugs, now new worries and the ongoing problems that some patients have using inhalers are bringing change.


  
Automated synthesis on a hub-and-spoke system 期刊论文
NATURE, 2020, 579 (7799) : 346-348
作者:  Bae-Jump, Victoria L.;  Levine, Douglas A.
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/03

A non-linear platform for flow chemistry.


Organic compounds can be synthesized in a continuous flow of solutions, but the need to balance mass flow across multiple reactors complicates the development of such systems. A new platform for flow chemistry addresses this issue.


  
CORONAVIRUS DIARIES: A NEW WORLD OF WORK 期刊论文
NATURE, 2020, 581 (7807) : 225-227
作者:  Maxmen, Amy
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/03

John Tregoning gets to grips with a new world of work.


John Tregoning gets to grips with a new world of work.