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Human impacts on polycyclic aromatic hydrocarbon distribution in Chinese intertidal zones 期刊论文
NATURE SUSTAINABILITY, 2020
作者:  Lv, Min;  Luan, Xiaolin;  Liao, Chunyang;  Wang, Dongqi;  Liu, Dongyan;  Zhang, Gan;  Jiang, Guibin;  Chen, Lingxin
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/06
Representing the function and sensitivity of coastal interfaces in Earth system models 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Ward, Nicholas D.;  Megonigal, J. Patrick;  Bond-Lamberty, Ben;  Bailey, Vanessa L.;  Butman, David;  Canuel, Elizabeth A.;  Diefenderfer, Heida;  Ganju, Neil K.;  Goni, Miguel A.;  Graham, Emily B.;  Hopkinson, Charles S.;  Khangaonkar, Tarang;  Langley, J. Adam;  McDowell, Nate G.;  Myers-Pigg, Allison N.;  Neumann, Rebecca B.;  Osburn, Christopher L.;  Price, Rene M.;  Rowland, Joel;  Sengupta, Aditi;  Simard, Marc;  Thornton, Peter E.;  Tzortziou, Maria;  Vargas, Rodrigo;  Weisenhorn, Pamela B.;  Windham-Myers, Lisamarie
收藏  |  浏览/下载:13/0  |  提交时间:2020/05/20
Reduced efficiency of the Barents Sea cooling machine 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (7) : 661-+
作者:  Skagseth, Oystein;  Eldevik, Tor;  Arthun, Marius;  Asbjornsen, Helene;  Lien, Vidar S.;  Smedsrud, Lars H.
收藏  |  浏览/下载:9/0  |  提交时间:2020/05/20
Illuminating water cycle modifications and Earth system resilience in the Anthropocene 期刊论文
WATER RESOURCES RESEARCH, 2020, 56 (4)
作者:  Gleeson, Tom;  Wang-Erlandsson, Lan;  Porkka, Miina;  Zipper, Samuel C.;  Jaramillo, Fernando;  Gerten, Dieter;  Fetzer, Ingo;  Cornell, Sarah E.;  Piemontese, Luigi;  Gordon, Line J.;  Rockstroem, Johan;  Oki, Taikan;  Sivapalan, Murugesu;  Wada, Yoshihide;  Brauman, Kate A.;  Floerke, Martina;  Bierkens, Marc F. P.;  Lehner, Bernhard;  Keys, Patrick;  Kummu, Matti;  Wagener, Thorsten;  Dadson, Simon;  Troy, Tara J.;  Steffen, Will;  Falkenmark, Malin;  Famiglietti, James S.
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/02
water cycle  Anthropocene  global hydrology  planetary boundary  
Sustainability of global Golden Inland Waterways 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Wang, Yichu;  Chen, Xiabin;  Borthwick, Alistair G. L.;  Li, Tianhong;  Liu, Huaihan;  Yang, Shengfa;  Zheng, Chunmiao;  Xu, Jianhua;  Ni, Jinren
收藏  |  浏览/下载:9/0  |  提交时间:2020/05/13
Adaptive Multirate Mass Transfer (aMMT) Model: A New Approach to Upscale Regional-Scale Transport Under Transient Flow Conditions 期刊论文
WATER RESOURCES RESEARCH, 2020, 56 (2)
作者:  Guo, Zhilin;  Henri, Christopher V.;  Fogg, Graham E.;  Zhang, Yong;  Zheng, Chunmiao
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/02
aMMT  MRMT  upscaling  transport  transient flow  
When Do Complex Transport Dynamics Arise in Natural Groundwater Systems? 期刊论文
WATER RESOURCES RESEARCH, 2020, 56 (2)
作者:  Wu, J.;  Lester, D. R.;  Trefry, M. G.;  Metcalfe, G.
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/02
Darcy flow  tidal aquifer  poroelastic  solute transport  groundwater  
Caveolae in CNS arterioles mediate neurovascular coupling 期刊论文
NATURE, 2020
作者:  Huang, Weijiao;  Masureel, Matthieu;  Qu, Qianhui;  Janetzko, John;  Inoue, Asuka;  Kato, Hideaki E.;  Robertson, Michael J.;  Nguyen, Khanh C.;  Glenn, Jeffrey S.;  Skiniotis, Georgios;  Kobilka, Brian K.
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/03

Caveolae in arteriolar endothelial cells-but not those in neighbouring smooth muscle cells-have a key role in neurovascular coupling, an essential function for meeting acute brain energy demand.


Proper brain function depends on neurovascular coupling: neural activity rapidly increases local blood flow to meet moment-to-moment changes in regional brain energy demand(1). Neurovascular coupling is the basis for functional brain imaging(2), and impaired neurovascular coupling is implicated in neurodegeneration(1). The underlying molecular and cellular mechanisms of neurovascular coupling remain poorly understood. The conventional view is that neurons or astrocytes release vasodilatory factors that act directly on smooth muscle cells (SMCs) to induce arterial dilation and increase local blood flow(1). Here, using two-photon microscopy to image neural activity and vascular dynamics simultaneously in the barrel cortex of awake mice under whisker stimulation, we found that arteriolar endothelial cells (aECs) have an active role in mediating neurovascular coupling. We found that aECs, unlike other vascular segments of endothelial cells in the central nervous system, have abundant caveolae. Acute genetic perturbations that eliminated caveolae in aECs, but not in neighbouring SMCs, impaired neurovascular coupling. Notably, caveolae function in aECs is independent of the endothelial NO synthase (eNOS)-mediated NO pathway. Ablation of both caveolae and eNOS completely abolished neurovascular coupling, whereas the single mutants exhibited partial impairment, revealing that the caveolae-mediated pathway in aECs is a major contributor to neurovascular coupling. Our findings indicate that vasodilation is largely mediated by endothelial cells that actively relay signals from the central nervous system to SMCs via a caveolae-dependent pathway.


  
The downstream air pollution impacts of the transition from coal to natural gas in the United States 期刊论文
NATURE SUSTAINABILITY, 2020, 3 (2) : 152-+
作者:  Burney, Jennifer A.
收藏  |  浏览/下载:8/0  |  提交时间:2020/05/13
Multiscale Feature-feature Interactions Control Patterns of Hyporheic Exchange in a Simulated Headwater Mountain Stream 期刊论文
WATER RESOURCES RESEARCH, 2019, 55 (12) : 10976-10992
作者:  Herzog, Skuyler P.;  Ward, Adam S.;  Wondzell, Steven M.
收藏  |  浏览/下载:8/0  |  提交时间:2020/02/16
hyporheic  multiscale modeling  river corridor  stream corridor  groundwater