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Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases 期刊论文
SCIENCE, 2019, 366 (6461) : 109-+
作者:  Kondo, Yasushi;  Ognjenovic, Jana;  Banerjee, Saikat;  Karandur, Deepti;  Merk, Alan;  Kulhanek, Kayla;  Wong, Kathryn;  Roose, Jeroen P.;  Subramaniam, Sriram;  Kuriyan, John
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/27
Atomically precise, custom-design origami graphene nanostructures 期刊论文
SCIENCE, 2019, 365 (6457) : 1036-+
作者:  Chen, Hui;  Zhang, Xian-Li;  Zhang, Yu-Yang;  Wang, Dongfei;  Bao, De-Liang;  Que, Yande;  Xiao, Wende;  Du, Shixuan;  Ouyang, Min;  Pantelides, Sokrates T.;  Gao, Hong-Jun
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Organoids-on-a-chip 期刊论文
SCIENCE, 2019, 364 (6444) : 960-965
作者:  Park, Sunghee Estelle;  Georgescu, Andrei;  Huh, Dongeun
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
VACCINOLOGY Structural topology defines protective CD8(+) T cell epitopes in the HIV proteome 期刊论文
SCIENCE, 2019, 364 (6439) : 480-+
作者:  Gaiha, Gaurav D.;  Rossin, Elizabeth J.;  Urbach, Jonathan;  Landeros, Christian;  Collins, David R.;  Nwonu, Chioma;  Muzhingi, Itai;  Anahtar, Melis N.;  Waring, Olivia M.;  Piechocka-Trocha, Alicja;  Waring, Michael;  Worrall, Daniel P.;  Ghebremichael, Musie S.;  Newman, Ruchi M.;  Power, Karen A.;  Allen, Todd M.;  Chodosh, James;  Walker, Bruce D.
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels 期刊论文
SCIENCE, 2019, 363 (6429) : 875-+
作者:  Schewe, Marcus;  Sun, Han;  Mert, Umit;  Mackenzie, Alexandra;  Pike, Ashley C. W.;  Schulz, Friederike;  Constantin, Cristina;  Vowinkel, Kirsty S.;  Conrad, Linus J.;  Kiper, Aytug K.;  Gonzalez, Wendy;  Musinszki, Marianne;  Tegtmeier, Marie;  Pryde, David C.;  Belabed, Hassane;  Nazare, Marc;  de Groot, Bert L.;  Decher, Niels;  Fakler, Bernd;  Carpenter, Elisabeth P.;  Tucker, Stephen J.;  Baukrowitz, Thomas
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Eliminating nonradiative decay in Cu(I) emitters: > 99% quantum efficiency and microsecond lifetime 期刊论文
SCIENCE, 2019, 363 (6427) : 601-606
作者:  Hamze, Rasha;  Peltier, Jesse L.;  Sylvinson, Daniel;  Jung, Moonchul;  Cardenas, Jose;  Haiges, Ralf;  Soleilhavoup, Michele;  Jazzar, Rodolphe;  Djurovich, Peter I.;  Bertrand, Guy;  Thompson, Mark E.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Structure of human TFIID and mechanism of TBP loading onto promoter DNA 期刊论文
SCIENCE, 2018, 362 (6421) : 1376-+
作者:  Patel, Avinash B.;  Louder, Robert K.;  Greber, Basil J.;  Grunberg, Sebastian;  Luo, Jie;  Fang, Jie;  Liu, Yutong;  Banish, Jeff;  Hahn, Steve;  Nogales, Eva
收藏  |  浏览/下载:17/0  |  提交时间:2019/11/27
Structural insight into precursor tRNA processing by yeast ribonuclease P 期刊论文
SCIENCE, 2018, 362 (6415) : 657-+
作者:  Lan, Pengfei;  Tan, Ming;  Zhang, Yuebin;  Niu, Shuangshuang;  Chen, Juan;  Shi, Shaohua;  Qiu, Shuwan;  Wang, Xuejuan;  Peng, Xiangda;  Cai, Gang;  Cheng, Hong;  Wu, Jian;  Li, Guohui;  Lei, Ming
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN 期刊论文
SCIENCE, 2018, 362 (6414) : 558-+
作者:  Sievers, Quinlan L.;  Petzold, Georg;  Bunker, Richard D.;  Renneville, Aline;  Slabicki, Mikolaj;  Liddicoat, Brian J.;  Abdulrahman, Wassim;  Mikkelsen, Tarjei;  Ebert, Benjamin L.;  Thoma, Nicolas H.
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27
Structural basis for the recognition of Sonic Hedgehog by human Patchedl 期刊论文
SCIENCE, 2018, 361 (6402)
作者:  Gong, Xin;  Qian, Hongwu;  Cao, Pingping;  Zhao, Xin;  Zhou, Qiang;  Lei, Jianlin;  Yan, Nieng
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27