Skeletal muscle thermogenesis enables aquatic life in the smallest marine mammal

doi:10.1126/science.abf4557

GSTDTAP > 气候变化

DOI	10.1126/science.abf4557
	Skeletal muscle thermogenesis enables aquatic life in the smallest marine mammal
	Traver Wright; Randall W. Davis; Heidi C. Pearson; Michael Murray; Melinda Sheffield-Moore
	2021-07-09
发表期刊	Science
出版年	2021
英文摘要	Several mammal species live in cold-water environments, enabled by adaptations such as blubber and large size. A notable exception to this rule is the sea otter, a species that is orders of magnitude smaller and skinnier than the others. It is known that the sea otter's unusually thick fur helps, but Wright et al. show that they are also internally warmed by thermogenic leak from skeletal muscle, a process that elevates their metabolic rate three times above that expected for their size. This mechanism is present even in infants with immature muscles, providing these animals with internal warmth from birth. Science , abf4557, this issue p. [223][1] Basal metabolic rate generally scales with body mass in mammals, and variation from predicted levels indicates adaptive metabolic remodeling. As a thermogenic adaptation for living in cool water, sea otters have a basal metabolic rate approximately three times that of the predicted rate; however, the tissue-level source of this hypermetabolism is unknown. Because skeletal muscle is a major determinant of whole-body metabolism, we characterized respiratory capacity and thermogenic leak in sea otter muscle. Compared with that of previously sampled mammals, thermogenic muscle leak capacity was elevated and could account for sea otter hypermetabolism. Muscle respiratory capacity was modestly elevated and reached adult levels in neonates. Premature metabolic development and high leak rate indicate that sea otter muscle metabolism is regulated by thermogenic demand and is the source of basal hypermetabolism. [1]: /lookup/doi/10.1126/science.abf4557
领域	气候变化 ; 资源环境
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文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/334279
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Traver Wright,Randall W. Davis,Heidi C. Pearson,et al. Skeletal muscle thermogenesis enables aquatic life in the smallest marine mammal[J]. Science,2021.
APA	Traver Wright,Randall W. Davis,Heidi C. Pearson,Michael Murray,&Melinda Sheffield-Moore.(2021).Skeletal muscle thermogenesis enables aquatic life in the smallest marine mammal.Science.
MLA	Traver Wright,et al."Skeletal muscle thermogenesis enables aquatic life in the smallest marine mammal".Science (2021).