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DOI | 10.1073/pnas.1818134116 |
Fluorescent reconstitution on deposition of PM2.5 in lung and extrapulmonary organs | |
Li, Donghai1; Li, Yongjian1; Li, Guiling2; Zhang, Yu3; Li, Jiang4; Chen, Haosheng1 | |
2019 | |
发表期刊 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
ISSN | 0027-8424 |
出版年 | 2019 |
卷号 | 116期号:7页码:2488-2493 |
文章类型 | Article |
语种 | 英语 |
国家 | Peoples R China |
英文摘要 | The deposition of PM2.5 (fine particulate matter in air with diameter smaller than 2.5 mu m) in lungs is harmful to human health. However, real-time observation on the deposition of particles in the acinar area of the lung is still a challenge in experiments. Here, a fluorescent imaging method is developed to visualize the deposition process with a high temporal and spatial resolution. The observations reveal that the deposition pattern is nonuniform, and the maximum deposition rate in the acinar area differs significantly from the prediction of the widely used average deposition model. The method is also used to find single particles in the kidney and liver, though such particles are commonly believed to be too large to enter the extrapulmonary organs. |
英文关键词 | PM2.5 lung air pollution particle deposition extrapulmonary organs |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000458365600020 |
WOS关键词 | AIR-POLLUTION ; PULMONARY DEPOSITION ; PARTICLES ; NANOPARTICLES ; EXPOSURE ; BODY |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/205220 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Tsinghua Univ, State Key Lab Tribol, Beijing 100084, Peoples R China; 2.Tsinghua Univ, Sch Pharmaceut Sci, Beijing 100084, Peoples R China; 3.Tsinghua Univ, Sch Med, Beijing 100084, Peoples R China; 4.Univ Sci & Technol, Sch Mech Engn, Beijing 100083, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Donghai,Li, Yongjian,Li, Guiling,et al. Fluorescent reconstitution on deposition of PM2.5 in lung and extrapulmonary organs[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2019,116(7):2488-2493. |
APA | Li, Donghai,Li, Yongjian,Li, Guiling,Zhang, Yu,Li, Jiang,&Chen, Haosheng.(2019).Fluorescent reconstitution on deposition of PM2.5 in lung and extrapulmonary organs.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,116(7),2488-2493. |
MLA | Li, Donghai,et al."Fluorescent reconstitution on deposition of PM2.5 in lung and extrapulmonary organs".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116.7(2019):2488-2493. |
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