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DOI | 10.1038/s41467-018-07934-z |
Regulation of FT splicing by an endogenous cue in temperate grasses | |
Qin, Zhengrui1; Wu, Jiajie2; Geng, Shuaifeng1; Feng, Nan; Chen, Fengjuan1,2; Kong, Xingchen1; Song, Gaoyuan1; Chen, Kai1; Li, Aili1; Mao, Long1; Wu, Liang1,3 | |
2019-01-23 | |
发表期刊 | Nature Communications |
ISSN | 2041-1723 |
出版年 | 2017 |
卷号 | 8 |
文章类型 | Article |
语种 | 英语 |
国家 | Peoples R China |
英文摘要 | Appropriate flowering timing is crucial for plant reproductive success. The florigen, FLOWERING LOCUS T (FT), interacts with 14-3-3 proteins and the bZIP transcription factor FD, functioning at core nodes in multiple flowering pathways. There are two FT homologues, FT1 and FT2, in Brachypodium distachyon. Here we show that FT2 undergoes age-dependent alternative splicing (AS), resulting in two splice variants (FT2 alpha and FT2 beta). The FT2 beta-encoded protein cannot interact with FD or 14-3-3s but is able to form heterodimers with FT2 alpha and FT1, thereby interfering with the florigen-mediated assembly of the flowering initiation complex. Notably, transgenic plants overproducing FT2 beta exhibit delayed flowering, while transgenic plants in which FT2 beta is silenced by an artificial microRNA display accelerated flowering, demonstrating a dominant-negative role of FT2 beta in flowering induction. Furthermore, we show that the AS splicing of FT2 is conserved in important cereal crops, such as barley and wheat. Collectively, these findings reveal a novel posttranscriptional mode of FT regulation in temperate grasses. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000393296300001 |
WOS关键词 | FLOWERING-LOCUS-T ; BRACHYPODIUM-DISTACHYON ; ARABIDOPSIS-THALIANA ; PHYTOCHROME-C ; FLORAL TRANSITION ; WHEAT ; TRANSCRIPTION ; PHOTOPERIOD ; RESPONSES ; VARIANTS |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/204180 |
专题 | 资源环境科学 |
作者单位 | 1.Chinese Acad Agr Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Inst Crop Sci, Beijing 100081, Peoples R China; 2.Shandong Agr Univ, State Key Lab Crop Biol, Tai An 271018, Shandong, Peoples R China; 3.Zhejiang Univ, Dept Agron, Coll Agr & Biotechnol, Hangzhou 310058, Zhejiang, Peoples R China |
推荐引用方式 GB/T 7714 | Qin, Zhengrui,Wu, Jiajie,Geng, Shuaifeng,et al. Regulation of FT splicing by an endogenous cue in temperate grasses[J]. Nature Communications,2019,8. |
APA | Qin, Zhengrui.,Wu, Jiajie.,Geng, Shuaifeng.,Feng, Nan.,Chen, Fengjuan.,...&Wu, Liang.(2019).Regulation of FT splicing by an endogenous cue in temperate grasses.Nature Communications,8. |
MLA | Qin, Zhengrui,et al."Regulation of FT splicing by an endogenous cue in temperate grasses".Nature Communications 8(2019). |
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