Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1038/ncomms15980 |
Irrational behavior in C. elegans arises from asymmetric modulatory effects within single sensory neurons | |
Iwanir, Shachar; Ruach, Rotem; Itskoyits, Eyal; Pritz, Christian O.; Bokman, Eduard; Zaslayer, Alon | |
2019-07-19 | |
发表期刊 | NATURE COMMUNICATIONS
![]() |
ISSN | 2041-1723 |
出版年 | 2019 |
卷号 | 10 |
文章类型 | Article |
语种 | 英语 |
国家 | Israel |
英文摘要 | C. elegans worms exhibit a natural chemotaxis towards food cues. This provides a potential platform to study the interactions between stimulus valence and innate behavioral preferences. Here we perform a comprehensive set of choice assays to measure worms' relative preference towards various attractants. Surprisingly, we find that when facing a combination of choices, worms' preferences do not always follow value-based hierarchy. In fact, the innate chemotaxis behavior in worms robustly violates key rationality paradigms of transitivity, independence of irrelevant alternatives and regularity. These violations arise due to asymmetric modulatory effects between the presented options. Functional analysis of the entire chemosensory system at a single-neuron resolution, coupled with analyses of mutants, defective in individual neurons, reveals that these asymmetric effects originate in specific sensory neurons. |
领域 | 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000476471300011 |
WOS关键词 | CAENORHABDITIS-ELEGANS ; DECISION-MAKING ; DEPENDENT DECISIONS ; GUANYLYL CYCLASE ; RATIONAL CHOICE ; TRANSITIVITY ; VIOLATIONS ; PREFERENCES ; CHEMOTAXIS ; OLFACTION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/203376 |
专题 | 资源环境科学 |
作者单位 | Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, Edmond J Safra Campus, IL-9190401 Jerusalem, Israel |
推荐引用方式 GB/T 7714 | Iwanir, Shachar,Ruach, Rotem,Itskoyits, Eyal,et al. Irrational behavior in C. elegans arises from asymmetric modulatory effects within single sensory neurons[J]. NATURE COMMUNICATIONS,2019,10. |
APA | Iwanir, Shachar,Ruach, Rotem,Itskoyits, Eyal,Pritz, Christian O.,Bokman, Eduard,&Zaslayer, Alon.(2019).Irrational behavior in C. elegans arises from asymmetric modulatory effects within single sensory neurons.NATURE COMMUNICATIONS,10. |
MLA | Iwanir, Shachar,et al."Irrational behavior in C. elegans arises from asymmetric modulatory effects within single sensory neurons".NATURE COMMUNICATIONS 10(2019). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论