Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1038/ncomms14796 |
Coordinated representational reinstatement in the human hippocampus and lateral temporal cortex during episodic memory retrieval | |
Pacheco Estefan, D.1,2; Sanchez-Fibla, M.2; Duff, A.1; Principe, A.3,4; Rocamora, R.3,4,5; Zhang, H.6; Axmacher, N.6; Verschure, P. F. M. J.1,7,8 | |
2019-05-21 | |
发表期刊 | NATURE COMMUNICATIONS
![]() |
ISSN | 2041-1723 |
出版年 | 2019 |
卷号 | 10 |
文章类型 | Article |
语种 | 英语 |
国家 | Spain; Germany |
英文摘要 | Theoretical models of episodic memory have proposed that retrieval depends on interactions between the hippocampus and neocortex, where hippocampal reinstatement of item-context associations drives neocortical reinstatement of item information. Here, we simultaneously recorded intracranial EEG from hippocampus and lateral temporal cortex (LTC) of epilepsy patients who performed a virtual reality spatial navigation task. We extracted stimulus-specific representations of both item and item-context associations from the time-frequency patterns of activity in hippocampus and LTC. Our results revealed a double dissociation of representational reinstatement across time and space: an early reinstatement of item-context associations in hippocampus preceded a later reinstatement of item information in LTC. Importantly, reinstatement levels in hippocampus and LTC were correlated across trials, and the quality of LTC reinstatement was predicted by the magnitude of phase synchronization between hippocampus and LTC. These findings confirm that episodic memory retrieval in humans relies on coordinated representational interactions within a hippocampal-neocortical network. |
领域 | 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000468447700002 |
WOS关键词 | RECOGNITION MEMORY ; THETA OSCILLATIONS ; GAMMA POWER ; LOBE ; CONFIDENCE ; DYNAMICS ; NETWORK ; STIMULI ; RHYTHMS ; NEURONS |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/203244 |
专题 | 资源环境科学 |
作者单位 | 1.Inst Bioengn Catalonia IBEC, Lab Synthet Percept Emot & Cognit Syst SPECS, Barcelona 08028, Spain; 2.Univ Pompeu Fabra, Dept Informat & Commun Technol, Barcelona 08018, Spain; 3.Hosp del Mar, Dept Neurol, Epilepsy Monitoring Unit, Barcelona 08003, Spain; 4.Hosp del Mar, Med Res Inst, Barcelona 08003, Spain; 5.Univ Pompeu Fabra, Fac Hlth & Life Sci, Barcelona 08003, Spain; 6.Ruhr Univ Bochum, Dept Neuropsychol, Inst Cognit Neurosci, Fac Psychol, D-44801 Bochum, Germany; 7.Barcelona Inst Sci & Technol, Barcelona 08036, Spain; 8.ICREA, Passeig Lluis Companys 23, Barcelona 08010, Spain |
推荐引用方式 GB/T 7714 | Pacheco Estefan, D.,Sanchez-Fibla, M.,Duff, A.,et al. Coordinated representational reinstatement in the human hippocampus and lateral temporal cortex during episodic memory retrieval[J]. NATURE COMMUNICATIONS,2019,10. |
APA | Pacheco Estefan, D..,Sanchez-Fibla, M..,Duff, A..,Principe, A..,Rocamora, R..,...&Verschure, P. F. M. J..(2019).Coordinated representational reinstatement in the human hippocampus and lateral temporal cortex during episodic memory retrieval.NATURE COMMUNICATIONS,10. |
MLA | Pacheco Estefan, D.,et al."Coordinated representational reinstatement in the human hippocampus and lateral temporal cortex during episodic memory retrieval".NATURE COMMUNICATIONS 10(2019). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论