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DOI | 10.1126/science.aat3872 |
Directional control of a processive molecular hopper | |
Qing, Yujia; Ionescu, Sandra A.; Pulcu, Gokce Su; Bayley, Hagan | |
2018-08-31 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2018 |
卷号 | 361期号:6405页码:908-911 |
文章类型 | Article |
语种 | 英语 |
国家 | England |
英文摘要 | Intrigued by the potential of nanoscale machines, scientists have long attempted to control molecular motion. We monitored the individual 0.7-nanometer steps of a single molecular hopper as it moved in an electric field along a track in a nanopore controlled by a chemical ratchet. The hopper demonstrated characteristics desired in a moving molecule: defined start and end points, processivity, no chemical fuel requirement, directional motion, and external control. The hopper was readily functionalized to carry cargos. For example, a DNA molecule could be ratcheted along the track in either direction, a prerequisite for nanopore sequencing. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000443547000036 |
WOS关键词 | KINESIN ; PORE ; DNA ; MECHANISM ; NANOPORE |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/199482 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | Univ Oxford, Dept Chem, Oxford OX1 3TA, England |
推荐引用方式 GB/T 7714 | Qing, Yujia,Ionescu, Sandra A.,Pulcu, Gokce Su,et al. Directional control of a processive molecular hopper[J]. SCIENCE,2018,361(6405):908-911. |
APA | Qing, Yujia,Ionescu, Sandra A.,Pulcu, Gokce Su,&Bayley, Hagan.(2018).Directional control of a processive molecular hopper.SCIENCE,361(6405),908-911. |
MLA | Qing, Yujia,et al."Directional control of a processive molecular hopper".SCIENCE 361.6405(2018):908-911. |
条目包含的文件 | 条目无相关文件。 |
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