GSTDTAP  > 地球科学
DOI10.1126/science.aal2674
Eye patches: Protein assembly of index-gradient squid lenses
Cai, J.1; Townsend, J. P.2; Dodson, T. C.1; Heiney, P. A.1; Sweeney, A. M.1
2017-08-11
发表期刊SCIENCE
ISSN0036-8075
EISSN1095-9203
出版年2017
卷号357期号:6351页码:564-569
文章类型Article
语种英语
国家USA
英文摘要

A parabolic relationship between lens radius and refractive index allows spherical lenses to avoid spherical aberration. We show that in squid, patchy colloidal physics resulted from an evolutionary radiation of globular S-crystallin proteins. Small-angle x-ray scattering experiments on lens tissue show colloidal gels of S-crystallins at all radial positions. Sparse lens materials form via low-valence linkages between disordered loops protruding from the protein surface. The loops are polydisperse and bind via a set of hydrogen bonds between disordered side chains. Peripheral lens regions with low particle valence form stable, volume-spanning gels at low density, whereas central regions with higher average valence gel at higher densities. The proteins demonstrate an evolved set of linkers for self-assembly of nanoparticles into volumetric materials.


领域地球科学 ; 气候变化 ; 资源环境
收录类别SCI-E
WOS记录号WOS:000407324800035
WOS关键词GLUTATHIONE-S-TRANSFERASE ; CEPHALOPODS ; CRYSTALLINS ; SCATTERING ; EVOLUTION ; FISH ; GELS
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
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文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/196649
专题地球科学
资源环境科学
气候变化
作者单位1.Univ Penn, Dept Phys & Astron, Philadelphia, PA 19104 USA;
2.Univ Penn, Dept Biochem & Biophys, Philadelphia, PA 19104 USA
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Cai, J.,Townsend, J. P.,Dodson, T. C.,et al. Eye patches: Protein assembly of index-gradient squid lenses[J]. SCIENCE,2017,357(6351):564-569.
APA Cai, J.,Townsend, J. P.,Dodson, T. C.,Heiney, P. A.,&Sweeney, A. M..(2017).Eye patches: Protein assembly of index-gradient squid lenses.SCIENCE,357(6351),564-569.
MLA Cai, J.,et al."Eye patches: Protein assembly of index-gradient squid lenses".SCIENCE 357.6351(2017):564-569.
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