GSTDTAP

浏览/检索结果: 共8条,第1-8条 帮助

限定条件    
已选(0)清除 条数/页:   排序方式:
CAN THE WORLD MAKE ENOUGH CORONAVIRUS VACCINE? 期刊论文
NATURE, 2020, 580 (7805) : 578-580
作者:  Zhao, Chuangqi;  Zhang, Pengchao;  Zhou, Jiajia;  Qi, Shuanhu;  Yamauchi, Yoshihiro;  Shi, Ruirui;  Fang, Ruochen;  Ishida, Yasuhiro;  Wang, Shutao;  Tomsia, Antoni P.;  Liu, Mingjie;  Jiang, Lei
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

Researchers warn production constraints and hoarding could limit SARS-CoV-2 vaccine supplies.


Researchers warn production constraints and hoarding could limit SARS-CoV-2 vaccine supplies.


  
Hydropower Production Benefits More From 1.5 degrees C than 2 degrees C Climate Scenario 期刊论文
WATER RESOURCES RESEARCH, 2020, 56 (5)
作者:  Meng, Ying;  Liu, Junguo;  Leduc, Sylvain;  Mesfun, Sennai;  Kraxner, Florian;  Mao, Ganquan;  Qi, Wei;  Wang, Zifeng
收藏  |  浏览/下载:8/0  |  提交时间:2020/05/13
global warming  hydropower(sic)hydro-economic modeling  optimization model  ISIMIP  PCR-GLOBWB  protected areas  
The online competition between pro- and anti-vaccination views 期刊论文
NATURE, 2020, 582 (7811) : 230-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

Insights into the interactions between pro- and anti-vaccination clusters on Facebook can enable policies and approaches that attempt to interrupt the shift to anti-vaccination views and persuade undecided individuals to adopt a pro-vaccination stance.


Distrust in scientific expertise(1-14) is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks(2-4), as happened for measles in 2019(5,6). Homemade remedies(7,8) and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice(9-11). There is a lack of understanding about how this distrust evolves at the system level(13,14). Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change(11), and highlight the key role of network cluster dynamics in multi-species ecologies(15).


  
Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells 期刊论文
NATURE, 2020, 577 (7792) : 676-+
作者:  Zhao, Ruozhu;  Chen, Xin;  Ma, Weiwei;  Zhang, Jinyu;  Guo, Jie;  Zhong, Xiu;  Yao, Jiacheng;  Sun, Jiahui;  Rubinfien, Julian;  Zhou, Xuyu;  Wang, Jianbin;  Qi, Hai
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

Empirical and anecdotal evidence has associated stress with accelerated hair greying (formation of unpigmented hairs)(1,2), but so far there has been little scientific validation of this link. Here we report that, in mice, acute stress leads to hair greying through the fast depletion of melanocyte stem cells. Using a combination of adrenalectomy, denervation, chemogenetics(3,4), cell ablation and knockout of the adrenergic receptor specifically in melanocyte stem cells, we find that the stress-induced loss of melanocyte stem cells is independent of immune attack or adrenal stress hormones. Instead, hair greying results from activation of the sympathetic nerves that innervate the melanocyte stem-cell niche. Under conditions of stress, the activation of these sympathetic nerves leads to burst release of the neurotransmitter noradrenaline (also known as norepinephrine). This causes quiescent melanocyte stem cells to proliferate rapidly, and is followed by their differentiation, migration and permanent depletion from the niche. Transient suppression of the proliferation of melanocyte stem cells prevents stress-induced hair greying. Our study demonstrates that neuronal activity that is induced by acute stress can drive a rapid and permanent loss of somatic stem cells, and illustrates an example in which the maintenance of somatic stem cells is directly influenced by the overall physiological state of the organism.


Stress induces hair greying in mice through depletion of melanocyte stem cells, which is mediated by the activation of sympathetic nerves rather than through immune attack or adrenal stress hormones.


  
Efficient and equitable allocation of renewable portfolio standards targets among China's provinces 期刊论文
ENERGY POLICY, 2019, 125: 170-180
作者:  Wang, Ge;  Zhang, Qi;  Li, Yan;  Mclellan, Benjamin C.
收藏  |  浏览/下载:3/0  |  提交时间:2019/04/09
Target allocation  Renewable portfolio standard  Renewable energy development  China  
Enhanced agricultural sustainability through within-species diversification 期刊论文
NATURE SUSTAINABILITY, 2019, 2 (1) : 46-52
作者:  Yang, Li-Na;  Pan, Zhe-Chao;  Zhu, Wen;  Wu, E-Jiao;  He, Dun-Chun;  Yuan, Xiao;  Qin, Yan-Yu;  Wang, Ying;  Chen, Ruey-Shyang;  Thrall, Peter H.;  Burdon, Jeremy J.;  Shang, Li-Ping;  Sui, Qi-Jun;  Zhan, Jiasui
收藏  |  浏览/下载:6/0  |  提交时间:2020/08/19
Provably secure anonymous authenticated key agreement protocols with enhanced security models 期刊论文
SCIENCE, 2018, 360 (6387) : 27-28
作者:  Xie, Qi;  Tan, Xiao;  Hu, Bin;  Wang, Guilin;  Wong, Duncan S.;  Chen, Kefei;  Yu, XiuYuan
收藏  |  浏览/下载:18/0  |  提交时间:2019/11/27
Response to Comments on "Outburst flood at 1920 BCE supports historicity of China's Great Flood and the Xia dynasty" 期刊论文
SCIENCE, 2017, 355 (6332)
作者:  Wu, Qinglong;  Zhao, Zhijun;  Liu, Li;  Granger, Darryl E.;  Wang, Hui;  Cohen, David J.;  Wu, Xiaohong;  Ye, Maolin;  Bar-Yosef, Ofer;  Lu, Bin;  Zhang, Jin;  Zhang, Peizhen;  Yuan, Daoyang;  Qi, Wuyun;  Cai, Linhai;  Bai, Shibiao
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27