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Not all driver mutations are equal 期刊论文
NATURE, 2020, 580 (7805) : 595-596
作者:  Legendre, Lucas J.;  Rubilar-Rogers, David;  Musser, Grace M.;  Davis, Sarah N.;  Otero, Rodrigo A.;  Vargas, Alexander O.;  Clarke, Julia A.
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

A study of cancer-associated mutations in normal endometrial glands of the uterus has now been performed using whole-genome sequencing. The analysis sheds light on the early changes that lead to invasive disease.


  
Mutations in colon cancer match bacterial signature 期刊论文
NATURE, 2020, 580 (7802)
作者:  Gray, Alison C.
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/03

Studies have pointed to a link between colon cancer and a gut bacterium that produces DNA-damaging molecules. The discovery of a mutational signature linked to these bacteria in human colon cancer supports this association.


  
Cellular survival over genomic perfection 期刊论文
SCIENCE, 2019, 366 (6467) : 802-+
作者:  Nik-Zainal, Serena;  Hall, Benjamin A.
收藏  |  浏览/下载:0/0  |  提交时间:2020/02/17
Double trouble for cancer gene 期刊论文
SCIENCE, 2019, 366 (6466) : 685-686
作者:  Toker, Alex
收藏  |  浏览/下载:0/0  |  提交时间:2020/02/17
The treacheries of adaptation 期刊论文
SCIENCE, 2019, 366 (6464) : 418-419
作者:  Miller, Craig R.
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/27
Mobilizing Mutations Human Genetics in the Age of Patient Advocacy 期刊论文
SCIENCE, 2019, 365 (6460) : 1386-1386
作者:  Wilbrecht, Linda
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
How to lose tumor suppression 期刊论文
SCIENCE, 2019, 365 (6453) : 539-540
作者:  Lane, David Philip
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
Mutated clones are the new normal 期刊论文
SCIENCE, 2019, 364 (6444) : 938-939
作者:  Tomasetti, Cristian
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27
The paradox of mutations and cancer 期刊论文
SCIENCE, 2018, 362 (6417) : 893-894
作者:  Chanock, Stephen J.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Contingency and determinism in evolution: Replaying life's tape 期刊论文
SCIENCE, 2018, 362 (6415)
作者:  Blount, Zachary D.;  Lenski, Richard E.;  Losos, Jonathan B.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27