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Extant timetrees are consistent with a myriad of diversification histories 期刊论文
NATURE, 2020, 580 (7804) : 502-+
作者:  Bhaskar, M. K.;  Riedinger, R.;  Machielse, B.;  Levonian, D. S.;  Nguyen, C. T.;  Knall, E. N.;  Park, H.;  Englund, D.;  Loncar, M.;  Sukachev, D. D.;  Lukin, M. D.
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/03

An infinite number of alternative diversification scenarios-which may have markedly different, but equally plausible, dynamics-can underpin a given time-calibrated phylogeny of extant species, suggesting many previous studies have over-interpreted phylogenetic evidence.


Time-calibrated phylogenies of extant species (referred to here as '  extant timetrees'  ) are widely used for estimating diversification dynamics(1). However, there has been considerable debate surrounding the reliability of these inferences(2-5) and, to date, this critical question remains unresolved. Here we clarify the precise information that can be extracted from extant timetrees under the generalized birth-death model, which underlies most existing methods of estimation. We prove that, for any diversification scenario, there exists an infinite number of alternative diversification scenarios that are equally likely to have generated any given extant timetree. These '  congruent'  scenarios cannot possibly be distinguished using extant timetrees alone, even in the presence of infinite data. Importantly, congruent diversification scenarios can exhibit markedly different and yet similarly plausible dynamics, which suggests that many previous studies may have over-interpreted phylogenetic evidence. We introduce identifiable and easily interpretable variables that contain all available information about past diversification dynamics, and demonstrate that these can be estimated from extant timetrees. We suggest that measuring and modelling these identifiable variables offers a more robust way to study historical diversification dynamics. Our findings also make it clear that palaeontological data will continue to be crucial for answering some macroevolutionary questions.


  
The wide-binary origin of (2014) MU69-like Kuiper belt contact binaries 期刊论文
NATURE, 2020, 580 (7804) : 463-+
作者:  Jiao, Lin;  Howard, Sean;  Ran, Sheng;  Wang, Zhenyu;  Rodriguez, Jorge Olivares;  Sigrist, Manfred;  Wang, Ziqiang;  Butch, Nicholas P.;  Madhavan, Vidya
收藏  |  浏览/下载:71/0  |  提交时间:2020/07/03

Following its flyby and first imaging of the Pluto-Charon binary, the New Horizons spacecraft visited the Kuiper belt object (KBO) 2014 MU69 (also known as (486958) Arrokoth). The imaging showed MU69 to be a contact binary that rotates at a low spin period (15.92 hours), is made of two individual lobes connected by a narrow neck and has a high obliquity (about 98 degrees)(1), properties that are similar to those of other KBO contact binaries inferred through photometric observations(2). However, all scenarios suggested so far for the origins of such configurations(3-5) have failed to reproduce these properties and their probable frequent occurrence in the Kuiper belt. Here we show that semi-secular perturbations(6,7) operating on only ultrawide KBO binaries close to their stability limit can robustly lead to gentle, slow binary mergers at arbitrarily high obliquities but low rotational velocities, reproducing the characteristics of MU69 and other similar oblique contact binaries. Using N-body simulations, we find that approximately 15 per cent of all ultrawide binaries with a cosine-uniform inclination distribution(5,9) are likely to merge through this process. Moreover, we find that such mergers are sufficiently gentle to deform the shape of the KBO only slightly. The semi-secular contact binary formation channel not only explains the observed properties of MU69, but may also apply to other Kuiper belt or asteroid belt binaries and in the Solar System and extra-solar moon systems.


The high obliquity and low rotation period of the Kuiper belt object (2014) MU69 and other similar contact binaries is successfully reproduced from the collision and post-collision characteristics of initially wide binaries.


  
Synthesis of rare sugar isomers through site-selective epimerization 期刊论文
NATURE, 2020: 403-+
作者:  Jackson, Hartland W.;  Fischer, Jana R.;  Zanotelli, Vito R. T.;  Ali, H. Raza;  Mechera, Robert;  Soysal, Savas D.;  Moch, Holger;  Muenst, Simone;  Varga, Zsuzsanna;  Weber, Walter P.;  Bodenmiller, Bernd
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/03

Glycans have diverse physiological functions, ranging from energy storage and structural integrity to cell signalling and the regulation of intracellular processes(1). Although biomass-derived carbohydrates (such as d-glucose, d-xylose and d-galactose) are extracted on commercial scales, and serve as renewable chemical feedstocks and building blocks(2,3), there are hundreds of distinct monosaccharides that typically cannot be isolated from their natural sources and must instead be prepared through multistep chemical or enzymatic syntheses(4,5). These '  rare'  sugars feature prominently in bioactive natural products and pharmaceuticals, including antiviral, antibacterial, anticancer and cardiac drugs(6,7). Here we report the preparation of rare sugar isomers directly from biomass carbohydrates through site-selective epimerization reactions. Mechanistic studies establish that these reactions proceed under kinetic control, through sequential steps of hydrogen-atom abstraction and hydrogen-atom donation mediated by two distinct catalysts. This synthetic strategy provides concise and potentially extensive access to this valuable class of natural compounds.


Various rare sugars that cannot be isolated from natural sources are synthesized using light-driven epimerization, a process which may find application in other synthetic scenarios.


  
Impacts of global warming on the surface water balance components in Iran as simulated by RegCM4 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2019, 39 (5) : 2646-2658
作者:  Moslemzadeh, Elham;  Irannejad, Parviz;  Alizadeh-Choobari, Omid
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/26
global warming  precipitation  RCP4  5 and RCP8  5 scenarios  RegCM4  surface temperature  
Time of emergence in regional precipitation changes: an updated assessment using the CMIP5 multi-model ensemble 期刊论文
CLIMATE DYNAMICS, 2018, 51: 3179-3193
作者:  Thuy-Huong Nguyen;  Min, Seung-Ki;  Paik, Seungmok;  Lee, Donghyun
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/09
Time of emergence  Precipitation  CMIP5  RCP scenarios  Signal-to-noise ratio  
Climate change projections over China using regional climate models forced by two CMIP5 global models. Part II: projections of future climate 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2018, 38: E78-E94
作者:  Hui, Pinhong;  Tang, Jianping;  Wang, Shuyu;  Niu, Xiaorui;  Zong, Peishu;  Dong, Xinning
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/09
climate change  dynamical downscaling  different RCMs  CMIP5 global models  RCP scenarios  
Global projections of drought hazard in a warming climate: a prime for disaster risk management 期刊论文
CLIMATE DYNAMICS, 2018, 50: 2137-2155
作者:  Carrao, Hugo;  Naumann, Gustavo;  Barbosa, Paulo
收藏  |  浏览/下载:6/0  |  提交时间:2019/04/09
Drought hazard  Risk management  Global warming  CMIP5 models  ISI-MIP project  RCP scenarios  
Dust load and rainfall characteristics and their relationship over the South Asian monsoon region under various warming scenarios 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2017, 122 (15)
作者:  Singh, Charu;  Ganguly, Dilip;  Dash, S. K.
收藏  |  浏览/下载:6/0  |  提交时间:2019/04/09
coupled climate models  historical  warming scenarios  CMIP5  dust  rainfall  
Implications of future climate on water availability in the western Canadian river basins 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2017, 37 (7)
作者:  Dibike, Yonas;  39;Neil, Hayley
收藏  |  浏览/下载:0/0  |  提交时间:2019/04/09
water availability  climate change  western Canada  emissions scenarios  statistical downscaling  CMIP5  SPEI  
Winter climate changes over East Asian region under RCP scenarios using East Asian winter monsoon indices 期刊论文
CLIMATE DYNAMICS, 2017, 48
作者:  Hong, Ja-Young;  Ahn, Joong-Bae;  Jhun, Jong-Ghap
收藏  |  浏览/下载:4/0  |  提交时间:2019/04/09
Climate change  RCP scenarios  East Asian winter monsoon  CMIP5  Monsoon index