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Multi-year El Ni帽o events tied to the North Pacific Oscillation 期刊论文
Nature Communications, 2022
作者:  Ding, Ruiqiang;  Tseng, Yu‐;  Heng;  Di Lorenzo, Emanuele;  Shi, Liang;  Li, Jianping;  Yu, Jin-Yi;  Wang, Chunzai;  Sun, Cheng;  Luo, Jing-Jia;  Ha, Kyung‑;  Ja;  Hu, Zeng-Zhen;  Li, Feifei
收藏  |  浏览/下载:21/0  |  提交时间:2022/07/08
Decarbonising the iron and steel sector for a 2鈥壜癈 target using inherent waste streams 期刊论文
Nature Communications, 2022
作者:  Sun, Yongqi;  Tian, Sicong;  Ciais, Philippe;  Zeng, Zhenzhong;  Meng, Jing;  Zhang, Zuotai
收藏  |  浏览/下载:23/0  |  提交时间:2022/01/29
Coseismic debris remains in the orogen despite a decade of enhanced landsliding 期刊论文
Geophysical Research Letters, 2021
作者:  Lanxin Dai;  Gianvito Scaringi;  Xuanmei Fan;  Ali P. Yunus;  Jing Liu-Zeng;  Qiang Xu;  Runqiu Huang
收藏  |  浏览/下载:11/0  |  提交时间:2021/10/07
High-resolution mapping of ice cover changes in over 33,000 lakes across the North Temperate Zone 期刊论文
Geophysical Research Letters, 2021
作者:  Xinchi Wang;  Lian Feng;  Luke Gibson;  Wei Qi;  Junguo Liu;  Yi Zheng;  Jing Tang;  Zhenzhong Zeng;  Chunmiao Zheng
收藏  |  浏览/下载:11/0  |  提交时间:2021/10/07
SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model 期刊论文
Science, 2021
作者:  Jingxin Qiao;  Yue-Shan Li;  Rui Zeng;  Feng-Liang Liu;  Rong-Hua Luo;  Chong Huang;  Yi-Fei Wang;  Jie Zhang;  Baoxue Quan;  Chenjian Shen;  Xin Mao;  Xinlei Liu;  Weining Sun;  Wei Yang;  Xincheng Ni;  Kai Wang;  Ling Xu;  Zi-Lei Duan;  Qing-Cui Zou;  Hai-Lin Zhang;  Wang Qu;  Yang-Hao-Peng Long;  Ming-Hua Li;  Rui-Cheng Yang;  Xiaolong Liu;  Jing You;  Yangli Zhou;  Rui Yao;  Wen-Pei Li;  Jing-Ming Liu;  Pei Chen;  Yang Liu;  Gui-Feng Lin;  Xin Yang;  Jun Zou;  Linli Li;  Yiguo Hu;  Guang-Wen Lu;  Wei-Min Li;  Yu-Quan Wei;  Yong-Tang Zheng;  Jian Lei;  Shengyong Yang
收藏  |  浏览/下载:14/0  |  提交时间:2021/04/06
Atmospheric heating rate due to black carbon aerosols: Uncertainties and impact factors 期刊论文
ATMOSPHERIC RESEARCH, 2020, 240
作者:  Lu, Qiao;  Liu, Chao;  Zhao, Delong;  Zeng, Chen;  Li, Jing;  Lu, Chunsong;  Wang, Jiandong;  Zhu, Bin
收藏  |  浏览/下载:32/0  |  提交时间:2020/08/18
Black carbon  Radiative forcing  Heating rate  Vertical distribution  
Stratigraphy of the Von Kármán Crater based on Chang’E‐4 Lunar Penetrating Radar Data 期刊论文
Geophysical Research Letters, 2020
作者:  Ling Zhang;  Jing Li;  Zhaofa Zeng;  Yi Xu;  Cai Liu;  Shengbo Chen
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/14
Remarkable nucleation and growth of ultrafine particles from vehicular exhaust 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (7) : 3427-3432
作者:  Guo, Song;  Hu, Min;  Peng, Jianfei;  Wu, Zhijun;  Zamora, Misti L.;  Shang, Dongjie;  Du, Zhuofei;  Zheng, Jing;  Fang, Xin;  Tang, Rongzhi;  Wu, Yusheng;  Zeng, Limin;  Shuai, Shijin;  Zhang, Wenbin;  Wang, Yuan;  Ji, Yuemeng;  Li, Yixin;  Zhang, Annie L.;  Wang, Weigang;  Zhang, Fang;  Zhao, Jiayun;  Gong, Xiaoli;  Wang, Chunyu;  Molina, Mario J.;  Zhang, Renyi
收藏  |  浏览/下载:11/0  |  提交时间:2020/05/13
new particle formation  nucleation  ultrafine particles  growth  organics  
Improved protein structure prediction using potentials from deep learning 期刊论文
NATURE, 2020, 577 (7792) : 706-+
作者:  Ma, Runze;  Cao, Duanyun;  Zhu, Chongqin;  Tian, Ye;  Peng, Jinbo;  Guo, Jing;  Chen, Ji;  Li, Xin-Zheng;  Francisco, Joseph S.;  Zeng, Xiao Cheng;  Xu, Li-Mei;  Wang, En-Ge;  Jiang, Ying
收藏  |  浏览/下载:142/0  |  提交时间:2020/07/03

Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence(1). This problem is of fundamental importance as the structure of a protein largely determines its function(2)  however, protein structures can be difficult to determine experimentally. Considerable progress has recently been made by leveraging genetic information. It is possible to infer which amino acid residues are in contact by analysing covariation in homologous sequences, which aids in the prediction of protein structures(3). Here we show that we can train a neural network to make accurate predictions of the distances between pairs of residues, which convey more information about the structure than contact predictions. Using this information, we construct a potential of mean force(4) that can accurately describe the shape of a protein. We find that the resulting potential can be optimized by a simple gradient descent algorithm to generate structures without complex sampling procedures. The resulting system, named AlphaFold, achieves high accuracy, even for sequences with fewer homologous sequences. In the recent Critical Assessment of Protein Structure Prediction(5) (CASP13)-a blind assessment of the state of the field-AlphaFold created high-accuracy structures (with template modelling (TM) scores(6) of 0.7 or higher) for 24 out of 43 free modelling domains, whereas the next best method, which used sampling and contact information, achieved such accuracy for only 14 out of 43 domains. AlphaFold represents a considerable advance in protein-structure prediction. We expect this increased accuracy to enable insights into the function and malfunction of proteins, especially in cases for which no structures for homologous proteins have been experimentally determined(7).


  
Coupled Snow and Frozen Ground Physics Improves Cold Region Hydrological Simulations: An Evaluation at the upper Yangtze River Basin (Tibetan Plateau) 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (23) : 12985-13004
作者:  Qi, Jia;  Wang, Lei;  Zhou, Jing;  Song, Lei;  Li, Xiuping;  Zeng, Tian
收藏  |  浏览/下载:8/0  |  提交时间:2020/02/17