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Application potential of satellite thermal anomaly products in updating industrial emission inventory of China 期刊论文
Geophysical Research Letters, 2021
作者:  Rong Li;  Minghui Tao;  Meigen Zhang;  Liangfu Chen;  Lili Wang;  Yi Wang;  Xinjie He;  Lifei Wei;  Xin Mei;  Jun Wang
收藏  |  浏览/下载：23/0  |  提交时间：2021/04/20
Improved protein structure prediction using potentials from deep learning 期刊论文
NATURE, 2020, 577 (7792) : 706-+
作者:  Ma, Runze;  Cao, Duanyun;  Zhu, Chongqin;  Tian, Ye;  Peng, Jinbo;  Guo, Jing;  Chen, Ji;  Li, Xin-Zheng;  Francisco, Joseph S.;  Zeng, Xiao Cheng;  Xu, Li-Mei;  Wang, En-Ge;  Jiang, Ying
收藏  |  浏览/下载：157/0  |  提交时间：2020/07/03

Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence(1). This problem is of fundamental importance as the structure of a protein largely determines its function(2)  however, protein structures can be difficult to determine experimentally. Considerable progress has recently been made by leveraging genetic information. It is possible to infer which amino acid residues are in contact by analysing covariation in homologous sequences, which aids in the prediction of protein structures(3). Here we show that we can train a neural network to make accurate predictions of the distances between pairs of residues, which convey more information about the structure than contact predictions. Using this information, we construct a potential of mean force(4) that can accurately describe the shape of a protein. We find that the resulting potential can be optimized by a simple gradient descent algorithm to generate structures without complex sampling procedures. The resulting system, named AlphaFold, achieves high accuracy, even for sequences with fewer homologous sequences. In the recent Critical Assessment of Protein Structure Prediction(5) (CASP13)-a blind assessment of the state of the field-AlphaFold created high-accuracy structures (with template modelling (TM) scores(6) of 0.7 or higher) for 24 out of 43 free modelling domains, whereas the next best method, which used sampling and contact information, achieved such accuracy for only 14 out of 43 domains. AlphaFold represents a considerable advance in protein-structure prediction. We expect this increased accuracy to enable insights into the function and malfunction of proteins, especially in cases for which no structures for homologous proteins have been experimentally determined(7).


  
Influences of Atmospheric Pollution on the Contributions of Major Oxidation Pathways to PM2.5 Nitrate Formation in Beijing 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2019, 124 (7) : 4174-4185
作者:  Wang, Yan-Li;  Song, Wei;  Yang, Wen;  Sun, Xin-Chao;  Tong, Yin-Dong;  Wang, Xue-Mei;  Liu, Cong-Qiang;  Bai, Zhi-Peng;  Liu, Xue-Yan
收藏  |  浏览/下载：20/0  |  提交时间：2019/11/26
Spatiotemporal patterns of carbon storage in forest ecosystems in Hunan Province, China 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2019, 432: 656-666
作者:  Chen, Long-Chi;  Guan, Xin;  Li, Hai-Mei;  Wang, Qing-Kui;  Zhang, Wei-Dong;  Yang, Qing-Peng;  Wang, Si-Long
收藏  |  浏览/下载：20/0  |  提交时间：2019/04/09
Forest ecosystem  Carbon storage  Carbon density  Carbon sequestration  Spatiotemporal pattern  
A Nonstationary ENSO-NAO Relationship Due to AMO Modulation 期刊论文
JOURNAL OF CLIMATE, 2019, 32 (1) : 33-43
作者:  Zhang, Wenjun;  Mei, Xuebin;  Geng, Xin;  Turner, Andrew G.;  Jin, Fei-Fei
收藏  |  浏览/下载：16/0  |  提交时间：2019/04/09
ENSO  North Atlantic Oscillation  
Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Yang, Jin-Yu;  Deng, Xiang-Yu;  Li, Yi-Sheng;  Ma, Xian-Cai;  Feng, Jian-Xiong;  Yu, Bing;  Chen, Yang;  Luo, Yi-Ling;  Wang, Xi;  Chen, Mei-Ling;  Fang, Zhi-Xin;  Zheng, Fu-Xiang;  Li, Yi-Ping;  Zhong, Qian;  Kang, Tie-Bang;  Song, Li-Bing;  Xu, Rui-Hua;  Zeng, Mu-Sheng;  Chen, Wei;  Zhang, Hui;  Xie, Wei;  Gao, Song
收藏  |  浏览/下载：28/0  |  提交时间：2019/11/27
间作作物根系分泌物中诱导玉米BXs合成的信号物质研究 项目
项目编号：31600346； 经费：200000(CNY)； 起止日期：2017 / dc_date_end
项目负责人:  梅馨月
收藏  |  浏览/下载：19/0  |  提交时间：2019/04/11
流域监测与评估国际研究态势文献计量分析 快报文章
资源环境快报，2009年第19期
作者:  王雪梅;  张欣利;  陈春
收藏  |  浏览/下载：33/0  |  提交时间：2020/05/22