GSTDTAP

浏览/检索结果: 共8条,第1-8条 帮助

已选(0)清除 条数/页:   排序方式:
Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants 期刊论文
Science, 2021
作者:  Lingshu Wang;  Tongqing Zhou;  Yi Zhang;  Eun Sung Yang;  Chaim A. Schramm;  Wei Shi;  Amarendra Pegu;  Olamide K. Oloniniyi;  Amy R. Henry;  Samuel Darko;  Sandeep R. Narpala;  Christian Hatcher;  David R. Martinez;  Yaroslav Tsybovsky;  Emily Phung;  Olubukola M. Abiona;  Avan Antia;  Evan M. Cale;  Lauren A. Chang;  Misook Choe;  Kizzmekia S. Corbett;  Rachel L. Davis;  Anthony T. DiPiazza;  Ingelise J. Gordon;  Sabrina Helmold Hait;  Tandile Hermanus;  Prudence Kgagudi;  Farida Laboune;  Kwanyee Leung;  Tracy Liu;  Rosemarie D. Mason;  Alexandra F. Nazzari;  Laura Novik;  Sarah O’Connell;  Sijy O’Dell;  Adam S. Olia;  Stephen D. Schmidt;  Tyler Stephens;  Christopher D. Stringham;  Chloe Adrienna Talana;  I-Ting Teng;  Danielle A. Wagner;  Alicia T. Widge;  Baoshan Zhang;  Mario Roederer;  Julie E. Ledgerwood;  Tracy J. Ruckwardt;  Martin R. Gaudinski;  Penny L. Moore;  Nicole A. Doria-Rose;  Ralph S. Baric;  Barney S. Graham;  Adrian B. McDermott;  Daniel C. Douek;  Peter D. Kwong;  John R. Mascola;  Nancy J. Sullivan;  John Misasi
收藏  |  浏览/下载:21/0  |  提交时间:2021/08/17
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth 期刊论文
Science, 2021
作者:  Ryan S. Roark;  Hui Li;  Wilton B. Williams;  Hema Chug;  Rosemarie D. Mason;  Jason Gorman;  Shuyi Wang;  Fang-Hua Lee;  Juliette Rando;  Mattia Bonsignori;  Kwan-Ki Hwang;  Kevin O. Saunders;  Kevin Wiehe;  M. Anthony Moody;  Peter T. Hraber;  Kshitij Wagh;  Elena E. Giorgi;  Ronnie M. Russell;  Frederic Bibollet-Ruche;  Weimin Liu;  Jesse Connell;  Andrew G. Smith;  Julia DeVoto;  Alexander I. Murphy;  Jessica Smith;  Wenge Ding;  Chengyan Zhao;  Neha Chohan;  Maho Okumura;  Christina Rosario;  Yu Ding;  Emily Lindemuth;  Anya M. Bauer;  Katharine J. Bar;  David Ambrozak;  Cara W. Chao;  Gwo-Yu Chuang;  Hui Geng;  Bob C. Lin;  Mark K. Louder;  Richard Nguyen;  Baoshan Zhang;  Mark G. Lewis;  Donald D. Raymond;  Nicole A. Doria-Rose;  Chaim A. Schramm;  Daniel C. Douek;  Mario Roederer;  Thomas B. Kepler;  Garnett Kelsoe;  John R. Mascola;  Peter D. Kwong;  Bette T. Korber;  Stephen C. Harrison;  Barton F. Haynes;  Beatrice H. Hahn;  George M. Shaw
收藏  |  浏览/下载:20/0  |  提交时间:2021/01/15
Effect of decreasing biological lability on dissolved organic matter dynamics in streams 期刊论文
Water Resources Research, 2020
作者:  Angang Li;  Jennifer D. Drummond;  Jennifer C. Bowen;  Rose M. Cory;  Louis A. Kaplan;  Aaron I. Packman
收藏  |  浏览/下载:13/0  |  提交时间:2020/12/28
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Ozone depletion, ultraviolet radiation, climate change and prospects for a sustainable future 期刊论文
NATURE SUSTAINABILITY, 2019, 2 (7) : 569-579
作者:  Barnes, Paul W.;  Williamson, Craig E.;  Lucas, Robyn M.;  Robinson, Sharon A.;  Madronich, Sasha;  Paul, Nigel D.;  Bornman, Janet F.;  Bais, Alkiviadis F.;  Sulzberger, Barbara;  Wilson, Stephen R.;  Andrady, Anthony L.;  McKenzie, Richard L.;  Neale, Patrick J.;  Austin, Amy T.;  Bernhard, Germar H.;  Solomon, Keith R.;  Neale, Rachel E.;  Young, Paul J.;  Norval, Mary;  Rhodes, Lesley E.;  Hylander, Samuel;  Rose, Kevin C.;  Longstreth, Janice;  Aucamp, Pieter J.;  Ballare, Carlos L.;  Cory, Rose M.;  Flint, Stephan D.;  de Gruijl, Frank R.;  Haeder, Donat-P;  Heikkila, Anu M.;  Jansen, Marcel A. K.;  Pandey, Krishna K.;  Robson, T. Matthew;  Sinclair, Craig A.;  Wangberg, Sten-Ake;  Worrest, Robert C.;  Yazar, Seyhan;  Young, Antony R.;  Zepp, Richard G.
收藏  |  浏览/下载:15/0  |  提交时间:2020/08/19
Initial results from the New Horizons exploration of 2014 MU69, a small Kuiper Belt object 期刊论文
SCIENCE, 2019, 364 (6441) : 649-+
作者:  Stern, S. A.;  Weaver, H. A.;  Spencer, J. R.;  Olkin, C. B.;  Gladstone, G. R.;  Grundy, W. M.;  Moore, J. M.;  Cruikshank, D. P.;  Elliott, H. A.;  McKinnon, W. B.;  Parker, J. Wm.;  Verbiscer, A. J.;  Young, L. A.;  Aguilar, D. A.;  Albers, J. M.;  Andert, T.;  Andrews, J. P.;  Bagenal, F.;  Banks, M. E.;  Bauer, B. A.;  Bauman, J. A.;  Bechtold, K. E.;  Beddingfield, C. B.;  Behrooz, N.;  Beisser, K. B.;  Benecchi, S. D.;  Bernardoni, E.;  Beyer, R. A.;  Bhaskaran, S.;  Bierson, C. J.;  Binzel, R. P.;  Birath, E. M.;  Bird, M. K.;  Boone, D. R.;  Bowman, A. F.;  Bray, V. J.;  Britt, D. T.;  Brown, L. E.;  Buckley, M. R.;  Buie, M. W.;  Buratti, B. J.;  Burke, L. M.;  Bushman, S. S.;  Careich, B.;  Chaikin, A. L.;  Chavez, C. L.;  Cheng, A. F.;  Colwell, E. J.;  Conard, S. J.;  Conner, M. P.;  Conrad, C. A.;  Cook, J. C.;  Cooper, S. B.;  Custodio, O. S.;  Ore, C. M. Dalle;  Deboy, C. C.;  Dharmavaram, P.;  Dhingra, R. D.;  Dunn, G. F.;  Earle, A. M.;  Egan, A. F.;  Eisig, J.;  El-Maarry, M. R.;  Engelbrecht, C.;  Enke, B. L.;  Ercol, C. J.;  Fattig, E. D.;  Ferrell, C. L.;  Finley, T. J.;  Firer, J.;  Fischetti, J.;  Folkner, W. M.;  Fosbury, M. N.;  Fountain, G. H.;  Freeze, J. M.;  Gabasova, L.;  Glaze, L. S.;  Green, J. L.;  Griffith, G. A.;  Guo, Y.;  Hahn, M.;  Hals, D. W.;  Hamilton, D. P.;  Hamilton, S. A.;  Hanley, J. J.;  Harch, A.;  Harmon, K. A.;  Hart, H. M.;  Hayes, J.;  Hersman, C. B.;  Hill, M. E.;  Hill, T. A.;  Hofgartner, J. D.;  Holdridge, M. E.;  Horanyi, M.;  Hosadurga, A.;  Howard, A. D.;  Howett, C. J. A.;  Jaskulek, S. E.;  Jennings, D. E.;  Jensen, J. R.;  Jones, M. R.;  Kang, H. K.;  Katz, D. J.;  Kaufmann, D. E.;  Kavelaars, J. J.;  Keane, J. T.;  Keleher, G. P.;  Kinczyk, M.;  Kochte, M. C.;  Kolmnann, P.;  Krimigis, S. M.;  Kruizinga, G. L.;  Kusnierkiewicz, D. Y.;  Lahr, M. S.;  Lauer, T. R.;  Lawrence, G. B.;  Lee, J. E.;  Lessac-Chenen, E. J.;  Linscott, I. R.;  Lisse, C. M.;  Lunsford, A. W.;  Mages, D. M.;  Mallder, V. A.;  Martin, N. P.;  May, B. H.;  McComas, D. J.;  MeNutt, R. L., Jr.;  Mehoke, D. S.;  Mehoke, T. S.;  Nelson, D. S.;  Nguyen, H. D.;  Nunez, J. I.;  Ocampo, A. C.;  Owen, W. M.;  Oxton, G. K.;  Parker, A. H.;  Patzold, M.;  Pelgrift, J. Y.;  Pelletier, F. J.;  Pineau, J. P.;  Piquette, M. R.;  Porter, S. B.;  Protopapa, S.;  Quirico, E.;  Redfern, J. A.;  Regiec, A. L.;  Reitsema, H. J.;  Reuter, D. C.;  Richardson, D. C.;  Riedel, J. E.;  Ritterbush, M. A.;  Robbins, S. J.;  Rodgers, D. J.;  Rogers, G. D.;  Rose, D. M.;  Rosendal, P. E.;  Runyon, K. D.;  Ryschkewitsch, M. G.;  Saina, M. M.;  Salinas, M. J.;  Schenk, P. M.;  Scherrer, J. R.;  Schlei, W. R.;  Schmitt, B.;  Schultz, D. J.;  Schurr, D. C.;  Scipioni, F.;  Sepan, R. L.;  Shelton, R. G.;  Showalter, M. R.;  Simon, M.;  Singer, K. N.;  Stahlheber, E. W.;  Stanbridge, D. R.;  Stansberry, J. A.;  Steffi, A. J.;  Strobel, D. F.;  Stothoff, M. M.;  Stryk, T.;  Stuart, J. M.;  Summers, M. E.;  Tapley, M. B.;  Taylor, A.;  Taylor, H. W.;  Tedford, R. M.;  Throop, H. B.;  Turner, L. S.;  Umurhan, O. M.;  Van Eck, J.;  Velez, D.;  Versteeg, M. H.;  Vincent, M. A.;  Webbert, R. W.;  Weidner, S. E.;  Ii, G. E. Weigle;  Wendel, J. R.;  White, O. L.;  Whittenburg, K. E.;  Williams, B. G.;  Williams, K. E.;  Williams, S. P.;  Wimters, H. L.;  Zangari, A. M.;  Zurbuchen, T. H.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
Appreciation of 2017 GRL Peer Reviewers 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2018, 45 (9) : 4494-4528
作者:  Diffenbaugh, Noah;  Beal, Lisa;  Cardenas, M. Bayani;  Cobb, Kim;  Cory, Rose;  Cronin, Meghan;  Dombard, Andrew J.;  Hogg, Andrew;  Ilyina, Tatiana;  Korte, Monika;  Lu, Gang;  Magnusdottir, Gudrun;  Newman, Andrew V.;  Opher, Merav;  Ritsema, Jeroen;  Sprintall, Janet;  Stroeve, Julienne;  Thornton, Joel A.;  Williams, Paul D.;  Yau, Andrew
收藏  |  浏览/下载:17/0  |  提交时间:2019/04/09
Fabrication of fillable microparticles and other complex 3D microstructures 期刊论文
SCIENCE, 2017, 357 (6356) : 1138-+
作者:  McHugh, Kevin J.;  Nguyen, Thanh D.;  Linehan, Allison R.;  Yang, David;  Behrens, Adam M.;  Rose, Sviatlana;  Tochka, Zachary L.;  Tzeng, Stephany Y.;  Norman, James J.;  Anselmo, Aaron C.;  Xu, Xian;  Tomasic, Stephanie;  Taylor, Matthew A.;  Lu, Jennifer;  Guarecuco, Rohiverth;  Langer, Robert;  Jaklenec, Ana
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27