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Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants 期刊论文
Science, 2021
作者:  Meng Yuan;  Deli Huang;  Chang-Chun D. Lee;  Nicholas C. Wu;  Abigail M. Jackson;  Xueyong Zhu;  Hejun Liu;  Linghang Peng;  Marit J. van Gils;  Rogier W. Sanders;  Dennis R. Burton;  S. Momsen Reincke;  Harald Prüss;  Jakob Kreye;  David Nemazee;  Andrew B. Ward;  Ian A. Wilson
收藏  |  浏览/下载：11/0  |  提交时间：2021/08/17
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape 期刊论文
Science, 2021
作者:  Paul-Albert Koenig;  Hrishikesh Das;  Hejun Liu;  Beate M. Kümmerer;  Florian N. Gohr;  Lea-Marie Jenster;  Lisa D. J. Schiffelers;  Yonas M. Tesfamariam;  Miki Uchima;  Jennifer D. Wuerth;  Karl Gatterdam;  Natalia Ruetalo;  Maria H. Christensen;  Caroline I. Fandrey;  Sabine Normann;  Jan M. P. Tödtmann;  Steffen Pritzl;  Leo Hanke;  Jannik Boos;  Meng Yuan;  Xueyong Zhu;  Jonathan L. Schmid-Burgk;  Hiroki Kato;  Michael Schindler;  Ian A. Wilson;  Matthias Geyer;  Kerstin U. Ludwig;  B. Martin Hällberg;  Nicholas C. Wu;  Florian I. Schmidt
收藏  |  浏览/下载：20/0  |  提交时间：2021/02/17
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications 期刊论文
Science, 2020
作者:  Divij Mathew;  Josephine R. Giles;  Amy E. Baxter;  Derek A. Oldridge;  Allison R. Greenplate;  Jennifer E. Wu;  Cécile Alanio;  Leticia Kuri-Cervantes;  M. Betina Pampena;  Kurt D’Andrea;  Sasikanth Manne;  Zeyu Chen;  Yinghui Jane Huang;  John P. Reilly;  Ariel R. Weisman;  Caroline A. G. Ittner;  Oliva Kuthuru;  Jeanette Dougherty;  Kito Nzingha;  Nicholas Han;  Justin Kim;  Ajinkya Pattekar;  Eileen C. Goodwin;  Elizabeth M. Anderson;  Madison E. Weirick;  Sigrid Gouma;  Claudia P. Arevalo;  Marcus J. Bolton;  Fang Chen;  Simon F. Lacey;  Holly Ramage;  Sara Cherry;  Scott E. Hensley;  Sokratis A. Apostolidis;  Alexander C. Huang;  Laura A. Vella;  The UPenn COVID Processing Unit†;  Michael R. Betts;  Nuala J. Meyer;  E. John Wherry
收藏  |  浏览/下载：16/0  |  提交时间：2020/09/08
Structural basis of a shared antibody response to SARS-CoV-2 期刊论文
Science, 2020
作者:  Meng Yuan;  Hejun Liu;  Nicholas C. Wu;  Chang-Chun D. Lee;  Xueyong Zhu;  Fangzhu Zhao;  Deli Huang;  Wenli Yu;  Yuanzi Hua;  Henry Tien;  Thomas F. Rogers;  Elise Landais;  Devin Sok;  Joseph G. Jardine;  Dennis R. Burton;  Ian A. Wilson
收藏  |  浏览/下载：11/0  |  提交时间：2020/09/08
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model 期刊论文
Science, 2020
作者:  Thomas F. Rogers;  Fangzhu Zhao;  Deli Huang;  Nathan Beutler;  Alison Burns;  Wan-ting He;  Oliver Limbo;  Chloe Smith;  Ge Song;  Jordan Woehl;  Linlin Yang;  Robert K. Abbott;  Sean Callaghan;  Elijah Garcia;  Jonathan Hurtado;  Mara Parren;  Linghang Peng;  Sydney Ramirez;  James Ricketts;  Michael J. Ricciardi;  Stephen A. Rawlings;  Nicholas C. Wu;  Meng Yuan;  Davey M. Smith;  David Nemazee;  John R. Teijaro;  James E. Voss;  Ian A. Wilson;  Raiees Andrabi;  Bryan Briney;  Elise Landais;  Devin Sok;  Joseph G. Jardine;  Dennis R. Burton
收藏  |  浏览/下载：19/0  |  提交时间：2020/08/25
Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses 期刊论文
Science, 2020
作者:  Nicholas C. Wu;  Andrew J. Thompson;  Juhye M. Lee;  Wen Su;  Britni M. Arlian;  Jia Xie;  Richard A. Lerner;  Hui-Ling Yen;  Jesse D. Bloom;  Ian A. Wilson
收藏  |  浏览/下载：13/0  |  提交时间：2020/06/22
Effect of the plastic pollutant bisphenol A on the biology of aquatic organisms: A meta‐analysis 期刊论文
Global Change Biology, 2020
作者:  Nicholas C. Wu;  Frank Seebacher
收藏  |  浏览/下载：7/0  |  提交时间：2020/05/25
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV 期刊论文
Science, 2020
作者:  Meng Yuan;  Nicholas C. Wu;  Xueyong Zhu;  Chang-Chun D. Lee;  Ray T. Y. So;  Huibin Lv;  Chris K. P. Mok;  Ian A. Wilson
收藏  |  浏览/下载：15/0  |  提交时间：2020/05/13
Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design 期刊论文
SCIENCE, 2018, 359 (6373) : 290-+
作者:  Du, Yushen;  Xin, Li;  Shi, Yuan;  Zhang, Tian-Hao;  Wu, Nicholas C.;  Dai, Lei;  Gong, Danyang;  Brar, Gurpreet;  Shu, Sara;  Luo, Jiadi;  Reiley, William;  Tseng, Yen-Wen;  Bai, Hongyan;  Wu, Ting-Ting;  Wang, Jieru;  Shu, Yuelong;  Sun, Ren
收藏  |  浏览/下载：8/0  |  提交时间：2019/11/27
Integrated genomic and molecular characterization of cervical cancer 期刊论文
NATURE, 2017, 543 (7645) : 378-+
作者:  Burk, Robert D.;  Chen, Zigui;  Saller, Charles;  Tarvin, Katherine;  Carvalho, Andre L.;  Scapulatempo-Neto, Cristovam;  Silveira, Henrique C.;  Fregnani, Jose H.;  Creighton, Chad J.;  Anderson, Matthew L.;  Castro, Patricia;  Wang, Sophia S.;  Yau, Christina;  Benz, Christopher;  Robertson, A. Gordon;  Mungall, Karen;  Lim, Lynette;  Bowlby, Reanne;  Sadeghi, Sara;  Brooks, Denise;  Sipahimalani, Payal;  Mar, Richard;  Ally, Adrian;  Clarke, Amanda;  Mungall, Andrew J.;  Tam, Angela;  Lee, Darlene;  Chuah, Eric;  Schein, Jacqueline E.;  Tse, Kane;  Kasaian, Katayoon;  Ma, Yussanne;  Marra, Marco A.;  Mayo, Michael;  Balasundaram, Miruna;  Thiessen, Nina;  Dhalla, Noreen;  Carlsen, Rebecca;  Moore, Richard A.;  Holt, Robert A.;  Jones, Steven J. M.;  Wong, Tina;  Pantazi, Angeliki;  Parfenov, Michael;  Kucherlapati, Raju;  Hadjipanayis, Angela;  Seidman, Jonathan;  Kucherlapati, Melanie;  Ren, Xiaojia;  Xu, Andrew W.;  Yang, Lixing;  Park, Peter J.;  Lee, Semin;  Rabeno, Brenda;  Huelsenbeck-Dill, Lori;  Borowsky, Mark;  Cadungog, Mark;  Iacocca, Mary;  Petrelli, Nicholas;  Swanson, Patricia;  Ojesina, Akinyemi I.;  Le, Xuan;  Sandusky, George;  Adebamowo, Sally N.;  Akeredolu, Teniola;  Adebamowo, Clement;  Reynolds, Sheila M.;  Shmulevich, Ilya;  Shelton, Candace;  Crain, Daniel;  Mallery, David;  Curley, Erin;  Gardner, Johanna;  Penny, Robert;  Morris, Scott;  Shelton, Troy;  Liu, Jia;  Lolla, Laxmi;  Chudamani, Sudha;  Wu, Ye;  Birrer, Michael;  McLellan, Michael D.;  Bailey, Matthew H.;  Miller, Christopher A.;  Wyczalkowski, Matthew A.;  Fulton, Robert S.;  Fronick, Catrina C.;  Lu, Charles;  Mardis, Elaine R.;  Appelbaum, Elizabeth L.;  Schmidt, Heather K.;  Fulton, Lucinda A.;  Cordes, Matthew G.;  Li, Tiandao;  Ding, Li;  Wilson, Richard K.;  Rader, Janet S.;  Behmaram, Behnaz;  Uyar, Denise;  Bradley, William;  Wrangle, John;  Pastore, Alessandro;  Levine, Douglas A.;  Dao, Fanny;  Gao, Jianjiong;  Schultz, Nikolaus;  Sander, Chris;  Ladanyi, Marc;  Einstein, Mark;  Teeter, Randall;  Benz, Stephen;  Wentzensen, Nicolas;  Felau, Ina;  Zenklusen, Jean C.;  Bodelon, Clara;  Demchok, John A.;  Yang, Liming;  Sheth, Margi;  Ferguson, Martin L.;  Tarnuzzer, Roy;  Yang, Hannah;  Schiffman, Mark;  Zhang, Jiashan;  Wang, Zhining;  Davidsen, Tanja;  Olaniyan, Olayinka;  Hutter, Carolyn M.;  Sofia, Heidi J.;  Gordenin, Dmitry A.;  Chan, Kin;  Roberts, Steven A.;  Klimczak, Leszek J.;  Van Waes, Carter;  Chen, Zhong;  Saleh, Anthony D.;  Cheng, Hui;  Parfitt, Jeremy;  Bartlett, John;  Albert, Monique;  Arnaout, Angel;  Sekhon, Harman;  Gilbert, Sebastien;  Peto, Myron;  Myers, Jerome;  Harr, Jodi;  Eckman, John;  Bergsten, Julie;  Tucker, Kelinda;  Zach, Leigh Anne;  Karlan, Beth Y.;  Lester, Jenny;  Orsulic, Sandra;  Sun, Qiang;  Naresh, Rashi;  Pihl, Todd;  Wan, Yunhu;  Zaren, Howard;  Sapp, Jennifer;  Miller, Judy;  Drwiega, Paul;  Ojesina, Akinyemi I.;  Murray, Bradley A.;  Zhang, Hailei;  Cherniack, Andrew D.;  Sougnez, Carrie;  Pedamallu, Chandra Sekhar;  Lichtenstein, Lee;  Meyerson, Matthew;  Noble, Michael S.;  Heiman, David I.;  Voet, Doug;  Getz, Gad;  Saksena, Gordon;  Kim, Jaegil;  Shih, Juliann;  Cho, Juok;  Lawrence, Michael S.;  Gehlenborg, Nils;  Lin, Pei;  Beroukhim, Rameen;  Frazer, Scott;  Gabriel, Stacey B.;  Schumacher, Steven E.;  Leraas, Kristen M.;  Lichtenberg, Tara M.;  Zmuda, Erik;  Bowen, Jay;  Frick, Jessica;  Gastier-Foster, Julie M.;  Wise, Lisa;  Gerken, Mark;  Ramirez, Nilsa C.;  Danilova, Ludmila;  Cope, Leslie;  Baylin, Stephen B.;  Salvesen, Helga B.;  Vellano, Christopher P.;  Ju, Zhenlin;  Diao, Lixia;  Zhao, Hao;  Chong, Zechen;  Ryan, Michael C.;  Martinez-Ledesma, Emmanuel;  Verhaak, Roeland G.;  Byers, Lauren Averett;  Yuan, Yuan;  Chen, Ken;  Ling, Shiyun;  Mills, Gordon B.;  Lu, Yiling;  Akbani, Rehan;  Seth, Sahil;  Liang, Han;  Wang, Jing;  Han, Leng;  Weinstein, John N.;  Bristow, Christopher A.;  Zhang, Wei;  Mahadeshwar, Harshad S.;  Sun, Huandong;  Tang, Jiabin;  Zhang, Jianhua;  Song, Xingzhi;  Protopopov, Alexei;  Shaw, Kenna R. Mills;  Chin, Lynda;  Olabode, Oluwole;  Ojesina, Akinyemi I.;  DiSaia, Philip;  Radenbaugh, Amie;  Haussler, David;  Zhu, Jingchun;  Stuart, Josh;  Chalise, Prabhakar;  Koestler, Devin;  Fridley, Brooke L.;  Godwin, Andrew K.;  Madan, Rashna;  Ciriello, Giovanni;  Martinez, Cathleen;  Higgins, Kelly;  Bocklage, Therese;  Auman, J. Todd;  Perou, Charles M.;  Tan, Donghui;  Parker, Joel S.;  Hoadley, Katherine A.;  Wilkerson, Matthew D.;  Mieczkowski, Piotr A.;  Skelly, Tara;  Veluvolu, Umadevi;  Hayes, D. Neil;  Rathmell, W. Kimryn;  Hoyle, Alan P.;  Simons, Janae V.;  Wu, Junyuan;  Mose, Lisle E.;  Soloway, Matthew G.;  Balu, Saianand;  Meng, Shaowu;  Jefferys, Stuart R.;  Bodenheimer, Tom;  Shi, Yan;  Roach, Jeffrey;  Thorne, Leigh B.;  Boice, Lori;  Huang, Mei;  Jones, Corbin D.;  Zuna, Rosemary;  Walker, Joan;  Gunderson, Camille;  Snowbarger, Carie;  Brown, David;  Moxley, Katherine;  Moore, Kathleen;  Andrade, Kelsi;  Landrum, Lisa;  Mannel, Robert;  McMeekin, Scott;  Johnson, Starla;  Nelson, Tina;  Elishaev, Esther;  Dhir, Rajiv;  Edwards, Robert;  Bhargava, Rohit;  Tiezzi, Daniel G.;  Andrade, Jurandyr M.;  Noushmehr, Houtan;  Carlotti, Carlos Gilberto, Jr.;  Tirapelli, Daniela Pretti da Cunha;  Weisenberger, Daniel J.;  Van Den Berg, David J.;  Maglinte, Dennis T.;  Bootwalla, Moiz S.;  Lai, Phillip H.;  Triche, Timothy, Jr.;  Swisher, Elizabeth M.;  Agnew, Kathy J.;  Shelley, Carl Simon;  Laird, Peter W.;  Schwarz, Julie;  Grigsby, Perry;  Mutch, David
收藏  |  浏览/下载：14/0  |  提交时间：2019/04/09