中文版 | English

在结果中检索

GSTDTAP

浏览/检索结果: 共12条，第1-10条 帮助

已选(0)清除 条数/页：   排序方式：
The impacts of mangrove range expansion on wetland ecosystem services in the southeastern United States: Current understanding, knowledge gaps, and emerging research needs 期刊论文
Global Change Biology, 2022
作者:  Michael J. Osland;  A. Randall Hughes;  Anna R. Armitage;  Steven B. Scyphers;  Just Cebrian;  Savannah H. Swinea;  Christine C. Shepard;  Micheal S. Allen;  Laura C. Feher;  James A. Nelson;  Cherie L. O’;  Brien;  Colt ;  R. Sanspree;  Delbert L. Smee;  Caitlin M. Snyder;  Andrew P. Stetter;  Philip ;  W. Stevens;  Kathleen M. Swanson;  Lauren H. Williams;  Janell ;  M. Brush;  Joseph Marchionno;  Ré;  mi Bardou
收藏  |  浏览/下载：16/0  |  提交时间：2022/02/23
Earlier winter/spring runoff and snowmelt during warmer winters lead to lower summer chlorophyll-a in north temperate lakes 期刊论文
Global Change Biology, 2021
作者:  Allison R. Hrycik;  Peter D. F. Isles;  Rita Adrian;  Matthew Albright;  Linda C. Bacon;  Stella A. Berger;  Ruchi Bhattacharya;  Hans-Peter Grossart;  Josef Hejzlar;  Amy Lee Hetherington;  Lesley B. Knoll;  Alo Laas;  Cory P. McDonald;  Kellie Merrell;  Jens C. Nejstgaard;  Kirsten Nelson;  Peeter Nõ;  ges;  Andrew M. Paterson;  Rachel M. Pilla;  Dale M. Robertson;  Lars G. Rudstam;  James A. Rusak;  Steven Sadro;  Eugene A. Silow;  Jason D. Stockwell;  Huaxia Yao;  Kiyoko Yokota;  Donald C. Pierson
收藏  |  浏览/下载：15/0  |  提交时间：2021/07/27
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil 期刊论文
Science, 2021
作者:  Nuno R. Faria;  Thomas A. Mellan;  Charles Whittaker;  Ingra M. Claro;  Darlan da S. Candido;  Swapnil Mishra;  Myuki A. E. Crispim;  Flavia C. S. Sales;  Iwona Hawryluk;  John T. McCrone;  Ruben J. G. Hulswit;  Lucas A. M. Franco;  Mariana S. Ramundo;  Jaqueline G. de Jesus;  Pamela S. Andrade;  Thais M. Coletti;  Giulia M. Ferreira;  Camila A. M. Silva;  Erika R. Manuli;  Rafael H. M. Pereira;  Pedro S. Peixoto;  Moritz U. G. Kraemer;  Nelson Gaburo;  Cecilia da C. Camilo;  Henrique Hoeltgebaum;  William M. Souza;  Esmenia C. Rocha;  Leandro M. de Souza;  Mariana C. de Pinho;  Leonardo J. T. Araujo;  Frederico S. V. Malta;  Aline B. de Lima;  Joice do P. Silva;  Danielle A. G. Zauli;  Alessandro C. de S. Ferreira;  Ricardo P. Schnekenberg;  Daniel J. Laydon;  Patrick G. T. Walker;  Hannah M. Schlüter;  Ana L. P. dos Santos;  Maria S. Vidal;  Valentina S. Del Caro;  Rosinaldo M. F. Filho;  Helem M. dos Santos;  Renato S. Aguiar;  José L. Proença-Modena;  Bruce Nelson;  James A. Hay;  Mélodie Monod;  Xenia Miscouridou;  Helen Coupland;  Raphael Sonabend;  Michaela Vollmer;  Axel Gandy;  Carlos A. Prete;  Vitor H. Nascimento;  Marc A. Suchard;  Thomas A. Bowden;  Sergei L. K. Pond;  Chieh-Hsi Wu;  Oliver Ratmann;  Neil M. Ferguson;  Christopher Dye;  Nick J. Loman;  Philippe Lemey;  Andrew Rambaut;  Nelson A. Fraiji;  Maria do P. S. S. Carvalho;  Oliver G. Pybus;  Seth Flaxman;  Samir Bhatt;  Ester C. Sabino
收藏  |  浏览/下载：13/0  |  提交时间：2021/06/07
Fisheries rely on threatened salt marshes 期刊论文
Science, 2020
作者:  Ronald Baker;  Matthew D. Taylor;  Kenneth W. Able;  Michael W. Beck;  Just Cebrian;  Denise D. Colombano;  Rod M. Connolly;  Carolyn Currin;  Linda A. Deegan;  Ilka C. Feller;  Ben L. Gilby;  Matthew E. Kimball;  Thomas J. Minello;  Lawrence P. Rozas;  Charles Simenstad;  R. Eugene Turner;  Nathan J. Waltham;  Michael P. Weinstein;  Shelby L. Ziegler;  Philine S.E. zu Ermgassen;  Caitlin Alcott;  Scott B. Alford;  Myriam A. Barbeau;  Sarah C. Crosby;  Kate Dodds;  Alyssa Frank;  Janelle Goeke;  Lucy A. Goodridge Gaines;  Felicity E. Hardcastle;  Christopher J. Henderson;  W. Ryan James;  Matthew D. Kenworthy;  Justin Lesser;  Debbrota Mallick;  Charles W. Martin;  Ashley E. McDonald;  Catherine McLuckie;  Blair H. Morrison;  James A. Nelson;  Gregory S. Norris;  Jeff Ollerhead;  James W. Pahl;  Sarah Ramsden;  Jennifer S. Rehage;  James F. Reinhardt;  Ryan J. Rezek;  L. Mark Risse;  Joseph A.M. Smith;  Eric L. Sparks;  Lorie W. Staver
收藏  |  浏览/下载：15/0  |  提交时间：2020/11/09
Resource supply governs the apparent temperature dependence of animal production in stream ecosystems 期刊论文
Ecology Letters, 2020
作者:  James R. Junker;  Wyatt F. Cross;  Jonathan P. Benstead;  Alexander D. Huryn;  James M. Hood;  Daniel Nelson;  Gí;  sli M. Gí;  slason;  Jó;  n S. Ó;  lafsson
收藏  |  浏览/下载：8/0  |  提交时间：2020/10/12
Megacity and local contributions to regional air pollution: an aircraft case study over London 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (12) : 7193-7216
作者:  Ashworth, Kirsti;  Bucci, Silvia;  Gallimore, Peter J.;  Lee, Junghwa;  Nelson, Beth S.;  Sanchez-Marroquin, Alberto;  Schimpf, Marina B.;  Smith, Paul D.;  Drysdale, Will S.;  Hopkins, Jim R.;  Lee, James D.;  Pitt, Joe R.;  Di Carlo, Piero;  Krejci, Radovan;  McQuaid, James B.
收藏  |  浏览/下载：17/0  |  提交时间：2020/06/29
Discriminating alpha-synuclein strains in Parkinson's disease and multiple system atrophy 期刊论文
NATURE, 2020, 578 (7794) : 273-+
作者:  Senior, Andrew W.;  Evans, Richard;  Jumper, John;  Kirkpatrick, James;  Sifre, Laurent;  Green, Tim;  Qin, Chongli;  Zidek, Augustin;  Nelson, Alexander W. R.;  Bridgland, Alex;  Penedones, Hugo;  Petersen, Stig;  Simonyan, Karen;  Crossan, Steve;  Kohli, Pushmeet;  Jones, David T.;  Silver, David;  Kavukcuoglu, Koray;  Hassabis, Demis
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/03

Synucleinopathies are neurodegenerative diseases that are associated with the misfolding and aggregation of alpha-synuclein, including Parkinson'  s disease, dementia with Lewy bodies and multiple system atrophy(1). Clinically, it is challenging to differentiate Parkinson'  s disease and multiple system atrophy, especially at the early stages of disease(2). Aggregates of alpha-synuclein in distinct synucleinopathies have been proposed to represent different conformational strains of alpha-synuclein that can self-propagate and spread from cell to cell(3-6). Protein misfolding cyclic amplification (PMCA) is a technique that has previously been used to detect alpha-synuclein aggregates in samples of cerebrospinal fluid with high sensitivity and specificity(7,8). Here we show that the alpha-synuclein-PMCA assay can discriminate between samples of cerebrospinal fluid from patients diagnosed with Parkinson'  s disease and samples from patients with multiple system atrophy, with an overall sensitivity of 95.4%. We used a combination of biochemical, biophysical and biological methods to analyse the product of alpha-synuclein-PMCA, and found that the characteristics of the alpha-synuclein aggregates in the cerebrospinal fluid could be used to readily distinguish between Parkinson'  s disease and multiple system atrophy. We also found that the properties of aggregates that were amplified from the cerebrospinal fluid were similar to those of aggregates that were amplified from the brain. These findings suggest that alpha-synuclein aggregates that are associated with Parkinson'  s disease and multiple system atrophy correspond to different conformational strains of alpha-synuclein, which can be amplified and detected by alpha-synuclein-PMCA. Our results may help to improve our understanding of the mechanism of alpha-synuclein misfolding and the structures of the aggregates that are implicated in different synucleinopathies, and may also enable the development of a biochemical assay to discriminate between Parkinson'  s disease and multiple system atrophy.


Protein misfolding cyclic amplification (PMCA) technology can discriminate between patients with Parkinson'  s disease and patients with multiple system atrophy on the basis of the characteristics of the alpha-synuclein aggregates in the cerebrospinal fluid.


  
Assessing London CO2, CH4 and CO emissions using aircraft measurements and dispersion modelling 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (13) : 8931-8945
作者:  Pitt, Joseph R.;  Allen, Grant;  Bauguitte, Stephane J. -B.;  Gallagher, Martin W.;  Lee, James D.;  Drysdale, Will;  Nelson, Beth;  Manning, Alistair J.;  Palmer, Paul I.
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/27
Increased resource use efficiency amplifies positive response of aquatic primary production to experimental warming 期刊论文
GLOBAL CHANGE BIOLOGY, 2018, 24 (3) : 1069-1084
作者:  Hood, James M.;  Benstead, Jonathan P.;  Cross, Wyatt F.;  Huryn, Alexander D.;  Johnson, Philip W.;  Gislason, Gisli M.;  Junker, James R.;  Nelson, Daniel;  Olafsson, Jon S.;  Chau Tran
收藏  |  浏览/下载：9/0  |  提交时间：2019/04/09
climate change  ecosystem respiration  gross primary production  headwater streams  nutrient cycling  nutrient use efficiency  stream metabolism  temperature  
Biomass burning emissions in north Australia during the early dry season: an overview of the 2014 SAFIRED campaign 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2017, 17 (22)
作者:  Mallet, Marc D.;  Desservettaz, Maximilien J.;  Miljevic, Branka;  Milic, Andelija;  Ristovski, Zoran D.;  Alroe, Joel;  Cravigan, Luke T.;  Jayaratne, E. Rohan;  Paton-Walsh, Clare;  Griffith, David W. T.;  Wilson, Stephen R.;  Kettlewell, Graham;  van der Schoot, Marcel V.;  Selleck, Paul;  Reisen, Fabienne;  Lawson, Sarah J.;  Ward, Jason;  Harnwell, James;  Cheng, Min;  Gillett, Rob W.;  Molloy, Suzie B.;  Howard, Dean;  Nelson, Peter F.;  Morrison, Anthony L.;  Edwards, Grant C.;  Williams, Alastair G.;  Chambers, Scott D.;  Werczynski, Sylvester;  Williams, Leah R.;  Winton, V. Holly L.;  Atkinson, Brad;  Wang, Xianyu;  Keywood, Melita D.
收藏  |  浏览/下载：8/0  |  提交时间：2019/04/09