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Idealized model for the deflection of sediment into lateral branches of lowland rivers 期刊论文
Water Resources Research, 2020
作者:  K. Kä;  stner;  A. J. F. Hoitink
收藏  |  浏览/下载:0/0  |  提交时间:2020/05/20
Diversion of flow and sediment towards a side channel separated from a river by a longitudinal training dam 期刊论文
Water Resources Research, 2020
作者:  T. V. de Ruijsscher;  B. Vermeulen;  A. J. F. Hoitink
收藏  |  浏览/下载:6/0  |  提交时间:2020/05/13
Scale-Dependent Evanescence of River Dunes During Discharge Extremes 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (6)
作者:  Nagshband, S.;  Hoitink, A. J. F.
收藏  |  浏览/下载:0/0  |  提交时间:2020/07/02
Global-scale human impact on delta morphology has led to net land area gain 期刊论文
NATURE, 2020, 577 (7791) : 514-+
作者:  Nienhuis, J. H.;  Ashton, A. D.;  Edmonds, D. A.;  Hoitink, A. J. F.;  Kettner, A. J.;  Rowland, J. C.;  Tornqvist, T. E.
收藏  |  浏览/下载:8/0  |  提交时间:2020/05/13

River deltas rank among the most economically and ecologically valuable environments on Earth. Even in the absence of sea-level rise, deltas are increasingly vulnerable to coastal hazards as declining sediment supply and climate change alter their sediment budget, affecting delta morphology and possibly leading to erosion(1-3). However, the relationship between deltaic sediment budgets, oceanographic forces of waves and tides, and delta morphology has remained poorly quantified. Here we show how the morphology of about 11,000 coastal deltas worldwide, ranging from small bayhead deltas to mega-deltas, has been affected by river damming and deforestation. We introduce a model that shows that present-day delta morphology varies across a continuum between wave (about 80 per cent), tide (around 10 per cent) and river (about 10 per cent) dominance, but that most large deltas are tide- and river-dominated. Over the past 30 years, despite sea-level rise, deltas globally have experienced a net land gain of 54 +/- 12 square kilometres per year (2 standard deviations), with the largest 1 per cent of deltas being responsible for 30 per cent of all net land area gains. Humans are a considerable driver of these net land gains-25 per cent of delta growth can be attributed to deforestation-induced increases in fluvial sediment supply. Yet for nearly 1,000 deltas, river damming(4) has resulted in a severe (more than 50 per cent) reduction in anthropogenic sediment flux, forcing a collective loss of 12 +/- 3.5 square kilometres per year (2 standard deviations) of deltaic land. Not all deltas lose land in response to river damming: deltas transitioning towards tide dominance are currently gaining land, probably through channel infilling. With expected accelerated sea-level rise(5), however, recent land gains are unlikely to be sustained throughout the twenty-first century. Understanding the redistribution of sediments by waves and tides will be critical for successfully predicting human-driven change to deltas, both locally and globally.


A global study of river deltas shows a net increase in delta area by about 54 km(2) yr(-1) over the past 30 years, in part due to deforestation-induced sediment delivery increase.


  
ATP13A2 deficiency disrupts lysosomal polyamine export 期刊论文
NATURE, 2020, 578 (7795) : 419-+
作者:  Nienhuis, J. H.;  Ashton, A. D.;  Edmonds, D. A.;  Hoitink, A. J. F.;  Kettner, A. J.;  Rowland, J. C.;  Tornqvist, T. E.
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/03

ATP13A2 (PARK9) is a late endolysosomal transporter that is genetically implicated in a spectrum of neurodegenerative disorders, including Kufor-Rakeb syndrome-a parkinsonism with dementia(1)-and early-onset Parkinson'  s disease(2). ATP13A2 offers protection against genetic and environmental risk factors of Parkinson'  s disease, whereas loss of ATP13A2 compromises lysosomes(3). However, the transport function of ATP13A2 in lysosomes remains unclear. Here we establish ATP13A2 as a lysosomal polyamine exporter that shows the highest affinity for spermine among the polyamines examined. Polyamines stimulate the activity of purified ATP13A2, whereas ATP13A2 mutants that are implicated in disease are functionally impaired to a degree that correlates with the disease phenotype. ATP13A2 promotes the cellular uptake of polyamines by endocytosis and transports them into the cytosol, highlighting a role for endolysosomes in the uptake of polyamines into cells. At high concentrations polyamines induce cell toxicity, which is exacerbated by ATP13A2 loss due to lysosomal dysfunction, lysosomal rupture and cathepsin B activation. This phenotype is recapitulated in neurons and nematodes with impaired expression of ATP13A2 or its orthologues. We present defective lysosomal polyamine export as a mechanism for lysosome-dependent cell death that may be implicated in neurodegeneration, and shed light on the molecular identity of the mammalian polyamine transport system.


The lysosomal polyamine transporter ATP13A2 controls the cellular polyamine content, and impaired lysosomal polyamine export represents a lysosome-dependent cell death pathway that may be implicated in ATP13A2-associated neurodegeneration.


  
Subtidal Flow Reversal Associated With Sediment Accretion in a Delta Channel 期刊论文
WATER RESOURCES RESEARCH, 2019, 55 (12) : 10781-10795
作者:  Zhang, Wei;  Feng, Haochuan;  Zhu, Yuliang;  Zheng, Jinhai;  Hoitink, A. J. F.
收藏  |  浏览/下载:9/0  |  提交时间:2020/02/16
Future Change to Tide-Influenced Deltas 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2018, 45 (8) : 3499-3507
作者:  Nienhuis, Jaap H.;  Hoitink, A. J. F. (Ton);  Tornqvist, Torbjorn E.
收藏  |  浏览/下载:2/0  |  提交时间:2019/04/09
Application of a Line Laser Scanner for Bed Form Tracking in a Laboratory Flume 期刊论文
WATER RESOURCES RESEARCH, 2018, 54 (3) : 2078-2094
作者:  de Ruijsscher, T. V.;  Hoitink, A. J. F.;  Dinnissen, S.;  Vermeulen, B.;  Hazenberg, P.
收藏  |  浏览/下载:5/0  |  提交时间:2019/04/09
Prerequisites for Accurate Monitoring of River Discharge Based on Fixed-Location Velocity Measurements 期刊论文
WATER RESOURCES RESEARCH, 2018, 54 (2) : 1058-1076
作者:  Kastner, K.;  Hoitink, A. J. F.;  Torfs, P. J. J. F.;  Vermeulen, B.;  Ningsih, N. S.;  Pramulya, M.
收藏  |  浏览/下载:3/0  |  提交时间:2019/04/09
discharge  index velocity  velocity profile  rating curve  Indonesia  Kapuas River  
A Sharp View on River Dune Transition to Upper Stage Plane Bed 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2017, 44 (22)
作者:  Naqshband, S.;  Hoitink, A. J. F.;  McElroy, B.;  Hurther, D.;  Hulscher, S. J. M. H.
收藏  |  浏览/下载:1/0  |  提交时间:2019/04/09