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ECMWF与Atos成立天气和气候模拟卓越中心 快报文章
气候变化快报,2020年第20期
作者:  刘燕飞
Microsoft Word(15Kb)  |  收藏  |  浏览/下载:378/0  |  提交时间:2020/10/20
Weather & Climate Modelling  High-performance Computing  ECMWF  Artificial Intelligence  
The timing and effect of the earliest human arrivals in North America 期刊论文
NATURE, 2020
作者:  Lorena Becerra-Valdivia;  Thomas Higham
收藏  |  浏览/下载:27/0  |  提交时间:2020/08/09

The peopling of the Americas marks a major expansion of humans across the planet. However, questions regarding the timing and mechanisms of this dispersal remain, and the previously accepted model (termed '  Clovis-first'  )-suggesting that the first inhabitants of the Americas were linked with the Clovis tradition, a complex marked by distinctive fluted lithic points(1)-has been effectively refuted. Here we analyse chronometric data from 42 North American and Beringian archaeological sites using a Bayesian age modelling approach, and use the resulting chronological framework to elucidate spatiotemporal patterns of human dispersal. We then integrate these patterns with the available genetic and climatic evidence. The data obtained show that humans were probably present before, during and immediately after the Last Glacial Maximum (about 26.5-19 thousand years ago)(2,3)but that more widespread occupation began during a period of abrupt warming, Greenland Interstadial 1 (about 14.7-12.9 thousand years beforead 2000)(4). We also identify the near-synchronous commencement of Beringian, Clovis and Western Stemmed cultural traditions, and an overlap of each with the last dates for the appearance of 18 now-extinct faunal genera. Our analysis suggests that the widespread expansion of humans through North America was a key factor in the extinction of large terrestrial mammals.


A Bayesian age model suggests that human dispersal to the Americas probably began before the Last Glacial Maximum, overlapping with the last dates of appearance for several faunal genera.


  
Potential for large-scale CO2 removal via enhanced rock weathering with croplands 期刊论文
NATURE, 2020, 583 (7815) : 242-+
作者:  David J. Beerling;  Euripides P. Kantzas;  Mark R. Lomas;  Peter Wade;  Rafael M. Eufrasio;  Phil Renforth;  Binoy Sarkar;  M. Grace Andrews;  Rachael H. James;  Christopher R. Pearce;  Jean-Francois Mercure;  Hector Pollitt;  Philip B. Holden;  Neil R. Edwards;  Madhu Khanna;  Lenny Koh;  Shaun Quegan;  Nick F. Pidgeon;  Ivan A. Janssens;  James Hansen;  Steven A. Banwart
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/14

Enhanced silicate rock weathering (ERW), deployable with croplands, has potential use for atmospheric carbon dioxide (CO2) removal (CDR), which is now necessary to mitigate anthropogenic climate change(1). ERW also has possible co-benefits for improved food and soil security, and reduced ocean acidification(2-4). Here we use an integrated performance modelling approach to make an initial techno-economic assessment for 2050, quantifying how CDR potential and costs vary among nations in relation to business-as-usual energy policies and policies consistent with limiting future warming to 2 degrees Celsius(5). China, India, the USA and Brazil have great potential to help achieve average global CDR goals of 0.5 to 2gigatonnes of carbon dioxide (CO2) per year with extraction costs of approximately US$80-180 per tonne of CO2. These goals and costs are robust, regardless of future energy policies. Deployment within existing croplands offers opportunities to align agriculture and climate policy. However, success will depend upon overcoming political and social inertia to develop regulatory and incentive frameworks. We discuss the challenges and opportunities of ERW deployment, including the potential for excess industrial silicate materials (basalt mine overburden, concrete, and iron and steel slag) to obviate the need for new mining, as well as uncertainties in soil weathering rates and land-ocean transfer of weathered products.


  
Quantifying the uncertainty introduced by internal climate variability in projections of Canadian crop production 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (7)
作者:  Qian, Budong;  Jing, Qi;  Smith, Ward;  Grant, Brian;  Cannon, Alex J.;  Zhang, Xuebin
收藏  |  浏览/下载:9/0  |  提交时间:2020/08/18
climate change impacts  crop production  crop modelling  internal climate variability  uncertainty  
Uncertainties in macroeconomic assessments of low-carbon transition pathways - The case of the European iron and steel industry 期刊论文
ECOLOGICAL ECONOMICS, 2020, 172
作者:  Bachner, G.;  Mayer, J.;  Steininger, K. W.;  Anger-Kraavi, A.;  Smith, A.;  Barker, T. S.
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/02
Climate change mitigation  Uncertainty  Low carbon transition  Iron and steel  Macroeconomic modelling  Process emissions  
The phosphorus legacy offers opportunities for agro-ecological transition (France 1850-2075) 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (6)
作者:  Le Noe, J.;  Roux, N.;  Billen, G.;  Gingrich, S.;  Erb, K. -H.;  Krausmann, F.;  Thieu, V;  Silvestre, M.;  Garnier, J.
收藏  |  浏览/下载:9/0  |  提交时间:2020/08/18
phosphorus  legacy  agriculture  modelling  trajectories  scenario  
Coupling delay controls synchronized oscillation in the segmentation clock 期刊论文
NATURE, 2020
作者:  Yoshioka-Kobayashi, Kumiko;  Matsumiya, Marina;  Niino, Yusuke;  Isomura, Akihiro;  Kori, Hiroshi;  Miyawaki, Atsushi;  Kageyama, Ryoichiro
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/03

Individual cellular activities fluctuate but are constantly coordinated at the population level via cell-cell coupling. A notable example is the somite segmentation clock, in which the expression of clock genes (such as Hes7) oscillates in synchrony between the cells that comprise the presomitic mesoderm (PSM)(1,2). This synchronization depends on the Notch signalling pathway  inhibiting this pathway desynchronizes oscillations, leading to somite fusion(3-7). However, how Notch signalling regulates the synchronicity of HES7 oscillations is unknown. Here we establish a live-imaging system using a new fluorescent reporter (Achilles), which we fuse with HES7 to monitor synchronous oscillations in HES7 expression in the mouse PSM at a single-cell resolution. Wild-type cells can rapidly correct for phase fluctuations in HES7 oscillations, whereas the absence of the Notch modulator gene lunatic fringe (Lfng) leads to a loss of synchrony between PSM cells. Furthermore, HES7 oscillations are severely dampened in individual cells of Lfng-null PSM. However, when Lfng-null PSM cells were completely dissociated, the amplitude and periodicity of HES7 oscillations were almost normal, which suggests that LFNG is involved mostly in cell-cell coupling. Mixed cultures of control and Lfng-null PSM cells, and an optogenetic Notch signalling reporter assay, revealed that LFNG delays the signal-sending process of intercellular Notch signalling transmission. These results-together with mathematical modelling-raised the possibility that Lfng-null PSM cells shorten the coupling delay, thereby approaching a condition known as the oscillation or amplitude death of coupled oscillators(8). Indeed, a small compound that lengthens the coupling delay partially rescues the amplitude and synchrony of HES7 oscillations in Lfng-null PSM cells. Our study reveals a delay control mechanism of the oscillatory networks involved in somite segmentation, and indicates that intercellular coupling with the correct delay is essential for synchronized oscillation.


Monitoring cells of the mouse presomitic mesoderm using the Achilles reporter fused to HES7 sheds light on the mechanisms that underpin synchronous oscillations in the expression of clock genes between neighbouring cells.


  
Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system 期刊论文
NATURE, 2020, 577 (7789) : 271-+
作者:  Halpin-Healy, Tyler S.;  Klompe, Sanne E.;  Sternberg, Samuel H.;  Fernandez, Israel S.
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/03

Bacteria use adaptive immune systems encoded by CRISPR and Cas genes to maintain genomic integrity when challenged by pathogens and mobile genetic elements(1-3). Type I CRISPR-Cas systems typically target foreign DNA for degradation via joint action of the ribonucleoprotein complex Cascade and the helicase-nuclease Cas3(4,5), but nuclease-deficient type I systems lacking Cas3 have been repurposed for RNA-guided transposition by bacterial Tn7-like transposons(6,7). How CRISPR- and transposon-associated machineries collaborate during DNA targeting and insertion remains unknown. Here we describe structures of a TniQ-Cascade complex encoded by the Vibrio cholerae Tn6677 transposon using cryo-electron microscopy, revealing the mechanistic basis of this functional coupling. The cryo-electron microscopy maps enabled de novo modelling and refinement of the transposition protein TniQ, which binds to the Cascade complex as a dimer in a head-to-tail configuration, at the interface formed by Cas6 and Cas7 near the 3'  end of the CRISPR RNA (crRNA). The natural Cas8-Cas5 fusion protein binds the 5'  crRNA handle and contacts the TniQ dimer via a flexible insertion domain. A target DNA-bound structure reveals critical interactions necessary for protospacer-adjacent motif recognition and R-loop formation. This work lays the foundation for a structural understanding of how DNA targeting by TniQ-Cascade leads to downstream recruitment of additional transposase proteins, and will guide protein engineering efforts to leverage this system for programmable DNA insertions in genome-engineering applications.


  
Trophic control changes with season and nutrient loading in lakes 期刊论文
ECOLOGY LETTERS, 2020, 23 (8) : 1287-1297
作者:  Rogers, Tanya L.;  Munch, Stephan B.;  Stewart, Simon D.;  Palkovacs, Eric P.;  Giron-Nava, Alfredo;  Matsuzaki, Shin-ichiro S.;  Symons, Celia C.
收藏  |  浏览/下载:12/0  |  提交时间:2020/06/01
consumer control  empirical dynamic modelling  nutrients  resource control  species interactions  temperature  time series  
Warmer climate projections in EC-Earth3-Veg: the role of changes in the greenhouse gas concentrations from CMIP5 to CMIP6 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (5)
作者:  Wyser, Klaus;  Kjellstrom, Erik;  Koenigk, Torben;  Martins, Helena;  Doscher, Ralf
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/02
CMIP6  ScenarioMIP  climate modelling  climate projections  climate scenarios