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Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity 期刊论文
Science, 2021
作者:  Ke Xu;  Na Yin;  Min Peng;  Efstathios G. Stamatiades;  Amy Shyu;  Peng Li;  Xian Zhang;  Mytrang H. Do;  Zhaoquan Wang;  Kristelle J. Capistrano;  Chun Chou;  Andrew G. Levine;  Alexander Y. Rudensky;  Ming O. Li
收藏  |  浏览/下载：11/0  |  提交时间：2021/01/28
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文
Science, 2020
作者:  Lu Zhang;  Yao Zhao;  Yan Gao;  Lijie Wu;  Ruogu Gao;  Qi Zhang;  Yinan Wang;  Chengyao Wu;  Fangyu Wu;  Sudagar S. Gurcha;  Natacha Veerapen;  Sarah M. Batt;  Wei Zhao;  Ling Qin;  Xiuna Yang;  Manfu Wang;  Yan Zhu;  Bing Zhang;  Lijun Bi;  Xian’en Zhang;  Haitao Yang;  Luke W. Guddat;  Wenqing Xu;  Quan Wang;  Jun Li;  Gurdyal S. Besra;  Zihe Rao
收藏  |  浏览/下载：10/0  |  提交时间：2020/06/16
Sustainable production of value-added carbon nanomaterials from biomass pyrolysis 期刊论文
NATURE SUSTAINABILITY, 2020
作者:  Zhang, Shun;  Jiang, Shun-Feng;  Huang, Bao-Cheng;  Shen, Xian-Cheng;  Chen, Wen-Jing;  Zhou, Tian-Pei;  Cheng, Hui-Yuan;  Cheng, Bin-Hai;  Wu, Chang-Zheng;  Li, Wen-Wei;  Jiang, Hong;  Yu, Han-Qing
收藏  |  浏览/下载：20/0  |  提交时间：2020/05/20
Recycling and metabolic flexibility dictate life in the lower oceanic crust 期刊论文
NATURE, 2020, 579 (7798) : 250-+
作者:  Zhou, Peng;  Yang, Xing-Lou;  Wang, Xian-Guang;  Hu, Ben;  Zhang, Lei;  Zhang, Wei;  Si, Hao-Rui;  Zhu, Yan;  Li, Bei;  Huang, Chao-Lin;  Chen, Hui-Dong;  Chen, Jing;  Luo, Yun;  Guo, Hua;  Jiang, Ren-Di;  Liu, Mei-Qin;  Chen, Ying;  Shen, Xu-Rui;  Wang, Xi;  Zheng, Xiao-Shuang;  Zhao, Kai;  Chen, Quan-Jiao;  Deng, Fei;  Liu, Lin-Lin;  Yan, Bing;  Zhan, Fa-Xian;  Wang, Yan-Yi;  Xiao, Geng-Fu;  Shi, Zheng-Li
收藏  |  浏览/下载：37/0  |  提交时间：2020/05/13

The lithified lower oceanic crust is one of Earth'  s last biological frontiers as it is difficult to access. It is challenging for microbiota that live in marine subsurface sediments or igneous basement to obtain sufficient carbon resources and energy to support growth(1-3) or to meet basal power requirements(4) during periods of resource scarcity. Here we show how limited and unpredictable sources of carbon and energy dictate survival strategies used by low-biomass microbial communities that live 10-750 m below the seafloor at Atlantis Bank, Indian Ocean, where Earth'  s lower crust is exposed at the seafloor. Assays of enzyme activities, lipid biomarkers, marker genes and microscopy indicate heterogeneously distributed and viable biomass with ultralow cell densities (fewer than 2,000 cells per cm(3)). Expression of genes involved in unexpected heterotrophic processes includes those with a role in the degradation of polyaromatic hydrocarbons, use of polyhydroxyalkanoates as carbon-storage molecules and recycling of amino acids to produce compounds that can participate in redox reactions and energy production. Our study provides insights into how microorganisms in the plutonic crust are able to survive within fractures or porous substrates by coupling sources of energy to organic and inorganic carbon resources that are probably delivered through the circulation of subseafloor fluids or seawater.


  
Atomically precise, custom-design origami graphene nanostructures 期刊论文
SCIENCE, 2019, 365 (6457) : 1036-+
作者:  Chen, Hui;  Zhang, Xian-Li;  Zhang, Yu-Yang;  Wang, Dongfei;  Bao, De-Liang;  Que, Yande;  Xiao, Wende;  Du, Shixuan;  Ouyang, Min;  Pantelides, Sokrates T.;  Gao, Hong-Jun
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27
Terahertz field-induced ferroelectricity in quantum paraelectric SrTiO3 期刊论文
SCIENCE, 2019, 364 (6445) : 1079-+
作者:  Li, Xian;  Qiu, Tian;  Zhang, Jiahao;  Baldini, Edoardo;  Lu, Jian;  Rappe, Andrew M.;  Nelson, Keith A.
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/27
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma 期刊论文
SCIENCE, 2018, 361 (6399) : 290-295
作者:  Zhang, Jing;  Wu, Tao;  Simon, Jeremy;  Takada, Mamoru;  Saito, Ryoichi;  Fan, Cheng;  Liu, Xian-De;  Jonasch, Eric;  Xie, Ling;  Chen, Xian;  Yao, Xiaosai;  Teh, Bin Tean;  Tan, Patrick;  Zheng, Xingnan;  Li, Mingjie;  Lawrence, Cortney;  Fan, Jie;  Geng, Jiang;  Liu, Xijuan;  Hu, Lianxin;  Wang, Jun;  Liao, Chengheng;  Hong, Kai;  Zurlo, Giada;  Parker, Joel S.;  Auman, J. Todd;  Perou, Charles M.;  Rathmell, W. Kimryn;  Kim, William Y.;  Kirschner, Marc W.;  Kaelin, William G., Jr.;  Baldwin, Albert S.;  Zhang, Qing
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/27
Act1 is a negative regulator in T and B cells via direct inhibition of STAT3 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Zhang, Cun-Jin;  Wang, Chenhui;  Jiang, Meiling;  Gu, Chunfang;  Xiao, Jianxin;  Chen, Xing;  Martin, Bradley N.;  Tang, Fangqiang;  Yamamoto, Erin;  Xian, Yibo;  Wang, Han;  Li, Fengling;  Sartor, R. Balfour;  Smith, Howard;  Husni, M. Elaine;  Shi, Fu-Dong;  Gao, Ji;  Carman, Julie;  Dongre, Ashok;  McKarns, Susan C.;  Coppieters, Ken;  Jorgensen, Trine N.;  Leonard, Warren J.;  Li, Xiaoxia
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27
The evolutionary history of vertebrate RNA viruses 期刊论文
NATURE, 2018, 556 (7700) : 197-+
作者:  Shi, Mang;  Lin, Xian-Dan;  Chen, Xiao;  Tian, Jun-Hua;  Chen, Liang-Jun;  Li, Kun;  Wang, Wen;  Eden, John-Sebastian;  Shen, Jin-Jin;  Liu, Li;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/27
Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Yang, Jin-Yu;  Deng, Xiang-Yu;  Li, Yi-Sheng;  Ma, Xian-Cai;  Feng, Jian-Xiong;  Yu, Bing;  Chen, Yang;  Luo, Yi-Ling;  Wang, Xi;  Chen, Mei-Ling;  Fang, Zhi-Xin;  Zheng, Fu-Xiang;  Li, Yi-Ping;  Zhong, Qian;  Kang, Tie-Bang;  Song, Li-Bing;  Xu, Rui-Hua;  Zeng, Mu-Sheng;  Chen, Wei;  Zhang, Hui;  Xie, Wei;  Gao, Song
收藏  |  浏览/下载：11/0  |  提交时间：2019/11/27