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A comprehensive quantification of global nitrous oxide sources and sinks 期刊论文
Nature, 2020
作者:  Hanqin Tian;  Rongting Xu;  Josep G. Canadell;  Rona L. Thompson;  Wilfried Winiwarter;  Parvadha Suntharalingam;  Eric A. Davidson;  Philippe Ciais;  Robert B. Jackson;  Greet Janssens-Maenhout;  Michael J. Prather;  Pierre Regnier;  Naiqing Pan;  Shufen Pan;  Glen P. Peters;  Hao Shi;  Francesco N. Tubiello;  Sö;  nke Zaehle;  Feng Zhou;  Almut Arneth;  Gianna Battaglia;  Sarah Berthet;  Laurent Bopp;  Alexander F. Bouwman;  Erik T. Buitenhuis;  Jinfeng Chang;  Martyn P. Chipperfield;  Shree R. S. Dangal;  Edward Dlugokencky;  James W. Elkins;  Bradley D. Eyre;  Bojie Fu;  Bradley Hall;  Akihiko Ito;  Fortunat Joos;  Paul B. Krummel;  Angela Landolfi;  Goulven G. Laruelle;  Ronny Lauerwald;  Wei Li;  Sebastian Lienert;  Taylor Maavara;  Michael MacLeod;  Dylan B. Millet;  Stefan Olin;  Prabir K. Patra;  Ronald G. Prinn;  Peter A. Raymond;  Daniel J. Ruiz;  Guido R. van der Werf;  Nicolas Vuichard;  Junjie Wang;  Ray F. Weiss;  Kelley C. Wells;  Chris Wilson;  Jia Yang;  Yuanzhi Yao
收藏  |  浏览/下载：24/0  |  提交时间：2020/10/12
Editorial Expression of Concern: Quantized Majorana conductance 期刊论文
NATURE, 2020: 1-1
作者:  Ge, Peng;  Scholl, Dean;  Prokhorov, Nikolai S.;  Avaylon, Jaycob;  Shneider, Mikhail M.;  Browning, Christopher;  Buth, Sergey A.;  Plattner, Michel;  Chakraborty, Urmi;  Ding, Ke;  Leiman, Petr G.;  Miller, Jeff F.;  Zhou, Z. Hong
收藏  |  浏览/下载：8/0  |  提交时间：2020/07/03
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Structural basis for the docking of mTORC1 on the lysosomal surface 期刊论文
SCIENCE, 2019, 366 (6464) : 468-+
作者:  Rogala, Kacper B.;  Gu, Xin;  Kedir, Jibril F.;  Abu-Remaileh, Monther;  Bianchi, Laura F.;  Bottino, Alexia M. S.;  Dueholm, Rikke;  Niehaus, Anna;  Overwijn, Daan;  Fils, Ange-Celia Priso;  Zhou, Sherry X.;  Leary, Daniel;  Laqtom, Nouf N.;  Brignole, Edward J.;  Sabatini, David M.
收藏  |  浏览/下载：7/0  |  提交时间：2019/11/27
Torsional refrigeration by twisted, coiled, and supercoiled fibers 期刊论文
SCIENCE, 2019, 366 (6462) : 216-+
作者:  Wang, Run;  Fang, Shaoli;  Xiao, Yicheng;  Gao, Enlai;  Jiang, Nan;  Li, Yaowang;  Mou, Linlin;  Shen, Yanan;  Zhao, Wubin;  Li, Sitong;  Fonseca, Alexandre F.;  Galvao, Douglas S.;  Chen, Mengmeng;  He, Wenqian;  Yu, Kaiqing;  Lu, Hongbing;  Wang, Xuemin;  Qian, Dong;  Aliev, Ali E.;  Li, Na;  Haines, Carter S.;  Liu, Zhongsheng;  Mu, Jiuke;  Wang, Zhong;  Yin, Shougen;  Lima, Marcio D.;  An, Baigang;  Zhou, Xiang;  Liu, Zunfeng;  Baughman, Ray H.
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
The human imperative of stabilizing global climate change at 1.5 degrees C 期刊论文
SCIENCE, 2019, 365 (6459) : 1263-+
作者:  Hoegh-Guldberg, O.;  Jacob, D.;  Taylor, M.;  Bolanos, T. Guillen;  Bindi, M.;  Brown, S.;  Camilloni, I. A.;  Diedhiou, A.;  Djalante, R.;  Ebi, K.;  Engelbrecht, F.;  Guiot, J.;  Hijioka, Y.;  Mehrotra, S.;  Hope, C. W.;  Payne, A. J.;  Poertner, H. -O.;  Seneviratne, S. I.;  Thomas, A.;  Warren, R.;  Zhou, G.
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis 期刊论文
SCIENCE, 2019, 365 (6451) : 386-+
作者:  Chaurasia, Bhagirath;  Tippetts, Trevor S.;  Monibas, Rafael Mayoral;  Liu, Jinqi;  Li, Ying;  Wang, Liping;  Wilkerson, Joseph L.;  Sweeney, C. Rufus;  Pereira, Renato Felipe;  Sumida, Doris Hissako;  Maschek, J. Alan;  Cox, James E.;  Kaddai, Vincent;  Lancaster, Graeme Iain;  Siddique, Monowarul Mobin;  Poss, Annelise;  Pearson, Mackenzie;  Satapati, Santhosh;  Zhou, Heather;  McLaren, David G.;  Previs, Stephen F.;  Chen, Ying;  Qian, Ying;  Petrov, Aleksandr;  Wu, Margaret;  Shen, Xiaolan;  Yao, Jun;  Nunes, Christian N.;  Howard, Andrew D.;  Wang, Liangsu;  Erion, Mark D.;  Rutter, Jared;  Holland, William L.;  Kelley, David E.;  Summers, Scott A.
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27
Giant thermal Hall conductivity in the pseudogap phase of cuprate superconductors 期刊论文
NATURE, 2019, 571 (7765) : 376-+
作者:  Grissonnanche, G.;  Legros, A.;  Badoux, S.;  Lefrancois, E.;  Zatko, V.;  Lizaire, M.;  Laliberte, F.;  Gourgout, A.;  Zhou, J. -S.;  Pyon, S.;  Takayama, T.;  Takagi, H.;  Ono, S.;  Doiron-Leyraud, N.;  Taillefer, L.
收藏  |  浏览/下载：8/0  |  提交时间：2019/11/27
Response to Comment on "Quantifying hot carrier and thermal contributions in plasmonic photocatalysis" 期刊论文
SCIENCE, 2019, 364 (6439)
作者:  Zhou, Linan;  Swearer, Dayne F.;  Robatjazi, Hossein;  Alabastri, Alessandro;  Christopher, Phillip;  Carter, Emily A.;  Nordlander, Peter;  Halas, Naomi J.
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials 期刊论文
SCIENCE, 2018, 362 (6419)
作者:  Antonova-Koch, Yevgeniya;  Meister, Stephan;  Abraham, Matthew;  Luth, Madeline R.;  Ottilie, Sabine;  Lukens, Amanda K.;  Sakata-Kato, Tomoyo;  Vanaerschot, Manu;  Owen, Edward;  Rodriguez, Juan Carlos Jado;  Maher, Steven P.;  Calla, Jaeson;  Plouffe, David;  Zhong, Yang;  Chen, Kaisheng;  Chaumeau, Victor;  Conway, Amy J.;  McNamara, Case W.;  Ibanez, Maureen;  Gagaring, Kerstin;  Neria Serrano, Fernando;  Eribez, Korina;  Taggard, Cullin McLean;  Cheung, Andrea L.;  Lincoln, Christie;  Ambachew, Biniam;  Rouillier, Melanie;  Siegel, Dionicio;  Nosten, Francois;  Kyle, Dennis E.;  Gamo, Francisco-Javier;  Zhou, Yingyao;  Llinas, Manuel;  Fidock, David A.;  Wirth, Dyann F.;  Burrows, Jeremy;  Campo, Brice;  Winzeler, Elizabeth A.
收藏  |  浏览/下载：16/0  |  提交时间：2019/11/27