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Rate of mass loss from the Greenland Ice Sheet will exceed Holocene values this century 期刊论文
Nature, 2020
作者:  Jason P. Briner;  Joshua K. Cuzzone;  Jessica A. Badgeley;  Nicolá;  s E. Young;  Eric J. Steig;  Mathieu Morlighem;  Nicole-Jeanne Schlegel;  Gregory J. Hakim;  Joerg M. Schaefer;  Jesse V. Johnson;  Alia J. Lesnek;  Elizabeth K. Thomas;  Estelle Allan;  Ole Bennike;  Allison A. Cluett;  Beata Csatho;  Anne de Vernal;  Jacob Downs;  Eric Larour;  Sophie Nowicki
收藏  |  浏览/下载:10/0  |  提交时间:2020/10/12
Global status and conservation potential of reef sharks 期刊论文
Nature, 2020
作者:  M. Aaron MacNeil;  Demian D. Chapman;  Michelle Heupel;  Colin A. Simpfendorfer;  Michael Heithaus;  Mark Meekan;  Euan Harvey;  Jordan Goetze;  Jeremy Kiszka;  Mark E. Bond;  Leanne M. Currey-Randall;  Conrad W. Speed;  C. Samantha Sherman;  Matthew J. Rees;  Vinay Udyawer;  Kathryn I. Flowers;  Gina Clementi;  Jasmine Valentin-Albanese;  Taylor Gorham;  M. Shiham Adam;  Khadeeja Ali;  Fabiá;  n Pina-Amargó;  s;  Jorge A. Angulo-Valdé;  s;  Jacob Asher;  Laura Garcí;  a Barcia;  Océ;  ane Beaufort;  Cecilie Benjamin;  Anthony T. F. Bernard;  Michael L. Berumen;  Stacy Bierwagen;  Erika Bonnema;  Rosalind M. K. Bown;  Darcey Bradley;  Edd Brooks;  J. Jed Brown;  Dayne Buddo;  Patrick Burke;  Camila Cá;  ceres;  Diego Cardeñ;  osa;  Jeffrey C. Carrier;  Jennifer E. Caselle;  Venkatesh Charloo;  Thomas Claverie;  Eric Clua;  Jesse E. M. Cochran;  Neil Cook;  Jessica Cramp;  Brooke D’;  Alberto;  Martin de Graaf;  Mareike Dornhege;  Andy Estep;  Lanya Fanovich;  Naomi F. Farabough;  Daniel Fernando;  Anna L. Flam;  Camilla Floros;  Virginia Fourqurean;  Ricardo Garla;  Kirk Gastrich;  Lachlan George;  Rory Graham;  Tristan Guttridge;  Royale S. Hardenstine;  Stephen Heck;  Aaron C. Henderson;  Heidi Hertler;  Robert Hueter;  Mohini Johnson;  Stacy Jupiter;  Devanshi Kasana;  Steven T. Kessel;  Benedict Kiilu;  Taratu Kirata;  Baraka Kuguru;  Fabian Kyne;  Tim Langlois;  Elodie J. I. Lé;  ;  e;  Steve Lindfield;  Andrea Luna-Acosta;  Jade Maggs;  B. Mabel Manjaji-Matsumoto;  Andrea Marshall;  Philip Matich;  Erin McCombs;  Dianne McLean;  Llewelyn Meggs;  Stephen Moore;  Sushmita Mukherji;  Ryan Murray;  Muslimin Kaimuddin;  Stephen J. Newman;  Josep Nogué;  s;  Clay Obota;  Owen O’;  Shea;  Kennedy Osuka;  Yannis P. Papastamatiou;  Nishan Perera;  Bradley Peterson;  Alessandro Ponzo;  Andhika Prasetyo;  L. M. Sjamsul Quamar;  Jessica Quinlan;  Alexei Ruiz-Abierno;  Enric Sala;  Melita Samoilys;  Michelle Schä;  rer-Umpierre;  Audrey Schlaff;  Nikola Simpson;  Adam N. H. Smith;  Lauren Sparks;  Akshay Tanna;  Rubé;  n Torres;  Michael J. Travers;  Maurits van Zinnicq Bergmann;  Laurent Vigliola;  Juney Ward;  Alexandra M. Watts;  Colin Wen;  Elizabeth Whitman;  Aaron J. Wirsing;  Aljoscha Wothke;  Esteban Zarza-Gonzâ;  lez;  Joshua E. Cinner
收藏  |  浏览/下载:17/0  |  提交时间:2020/08/09
Enhanced mixing across the gyre boundary at the Gulf Stream front 期刊论文
Proceedings of the National Academy of Science, 2020
作者:  Jacob O. Wenegrat;  Leif N. Thomas;  Miles A. Sundermeyer;  John R. Taylor;  Eric A. D’Asaro;  Jody M. Klymak;  R. Kipp Shearman;  Craig M. Lee
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/14
Accelerating methane growth rate from 2010 to 2017: leading contributions from the tropics and East Asia 期刊论文
Atmospheric Chemistry and Physics, 2020
作者:  Yi Yin, Frederic Chevallier, Philippe Ciais, Philippe Bousquet, Marielle Saunois, Bo Zheng, John Worden, A. Anthony Bloom, Robert Parker, Daniel Jacob, Edward J. Dlugokencky, and Christian Frankenberg
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/14
HOW CONFERENCES WILL SURVIVE THE CORONAVIRUS SHOCK 期刊论文
NATURE, 2020, 582 (7811) : 166-167
作者:  Amor, Corina;  Feucht, Judith;  Leibold, Josef;  Ho, Yu-Jui;  Zhu, Changyu;  Alonso-Curbelo, Direna;  Mansilla-Soto, Jorge;  Boyer, Jacob A.;  Li, Xiang;  Giavridis, Theodoros;  Kulick, Amanda;  Houlihan, Shauna;  Peerschke, Ellinor;  Friedman, Scott L.;  Ponomarev, Vladimir
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/03
IGF1R is an entry receptor for respiratory syncytial virus (vol 53, pg 861, 2020) 期刊论文
NATURE, 2020, 583 (7815) : E22-E22
作者:  Smith, Jacob A.;  Wilson, Katy B.;  Sonstrom, Reilly E.;  Kelleher, Patrick J.;  Welch, Kevin D.;  Pert, Emmit K.;  Westendorff, Karl S.;  Dickie, Diane A.;  Wang, Xiaoping;  Pate, Brooks H.;  Harman, W. Dean
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/03

An amendment to this paper has been published and can be accessed via a link at the top of the paper.


  
Characterization of organic aerosol across the global remote troposphere: a comparison of ATom measurements and global chemistry models 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (8) : 4607-4635
作者:  Hodzic, Alma;  Campuzano-Jost, Pedro;  Bian, Huisheng;  Chin, Mian;  Colarco, Peter R.;  Day, Douglas A.;  Froyd, Karl D.;  Heinold, Bernd;  Jo, Duseong S.;  Katich, Joseph M.;  Kodros, John K.;  Nault, Benjamin A.;  Pierce, Jeffrey R.;  Ray, Eric;  Schacht, Jacob;  Schill, Gregory P.;  Schroder, Jason C.;  Schwarz, Joshua P.;  Sueper, Donna T.;  Tegen, Ina;  Tilmes, Simone;  Tsigaridis, Kostas;  Yu, Pengfei;  Jimenez, Jose L.
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/02
Sediment controls dynamic behavior of a Cordilleran Ice Stream at the Last Glacial Maximum 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Cowan, Ellen A.;  Zellers, Sarah D.;  Mueller, Juliane;  Walczak, Maureen H.;  Worthington, Lindsay L.;  Caissie, Beth E.;  Clary, Wesley A.;  Jaeger, John M.;  Gulick, Sean P. S.;  Pratt, Jacob W.;  Mix, Alan C.;  Fallon, Stewart J.
收藏  |  浏览/下载:9/0  |  提交时间:2020/05/13
Electrical manipulation of a topological antiferromagnetic state 期刊论文
NATURE, 2020, 580 (7805) : 608-+
作者:  Chabon, Jacob J.;  Hamilton, Emily G.;  Kurtz, David M.;  Esfahani, Mohammad S.;  Moding, Everett J.;  Stehr, Henning;  Schroers-Martin, Joseph;  Nabet, Barzin Y.;  Chen, Binbin;  Chaudhuri, Aadel A.;  Liu, Chih Long;  Hui, Angela B.;  Jin, Michael C.;  Azad, Tej D.;  Almanza, Diego;  Jeon, Young-Jun;  Nesselbush, Monica C.;  Keh, Lyron Co Ting;  Bonilla, Rene F.;  Yoo, Christopher H.;  Ko, Ryan B.;  Chen, Emily L.;  Merriott, David J.;  Massion, Pierre P.;  Mansfield, Aaron S.;  Jen, Jin;  Ren, Hong Z.;  Lin, Steven H.;  Costantino, Christina L.;  Burr, Risa;  Tibshirani, Robert;  Gambhir, Sanjiv S.;  Berry, Gerald J.;  Jensen, Kristin C.;  West, Robert B.;  Neal, Joel W.;  Wakelee, Heather A.;  Loo, Billy W., Jr.;  Kunder, Christian A.;  Leung, Ann N.;  Lui, Natalie S.;  Berry, Mark F.;  Shrager, Joseph B.;  Nair, Viswam S.;  Haber, Daniel A.;  Sequist, Lecia V.;  Alizadeh, Ash A.;  Diehn, Maximilian
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/03

Room-temperature electrical switching of a topological antiferromagnetic state in polycrystalline Mn3Sn thin films is demonstrated using the same protocol as that used for conventional ferromagnetic metals.


Electrical manipulation of phenomena generated by nontrivial band topology is essential for the development of next-generation technology using topological protection. A Weyl semimetal is a three-dimensional gapless system that hosts Weyl fermions as low-energy quasiparticles(1-4). It has various exotic properties, such as a large anomalous Hall effect (AHE) and chiral anomaly, which are robust owing to the topologically protected Weyl nodes(1-16). To manipulate such phenomena, a magnetic version of Weyl semimetals would be useful for controlling the locations of Weyl nodes in the Brillouin zone. Moreover, electrical manipulation of antiferromagnetic Weyl metals would facilitate the use of antiferromagnetic spintronics to realize high-density devices with ultrafast operation(17,18). However, electrical control of a Weyl metal has not yet been reported. Here we demonstrate the electrical switching of a topological antiferromagnetic state and its detection by the AHE at room temperature in a polycrystalline thin film(19) of the antiferromagnetic Weyl metal Mn3Sn9,10,12,20, which exhibits zero-field AHE. Using bilayer devices composed of Mn3Sn and nonmagnetic metals, we find that an electrical current density of about 10(10) to 10(11) amperes per square metre induces magnetic switching in the nonmagnetic metals, with a large change in Hall voltage. In addition, the current polarity along the bias field and the sign of the spin Hall angle of the nonmagnetic metals-positive for Pt (ref. (21)), close to 0 for Cu and negative for W (ref. (22))-determines the sign of the Hall voltage. Notably, the electrical switching in the antiferromagnet is achieved with the same protocol as that used for ferromagnetic metals(23,24). Our results may lead to further scientific and technological advances in topological magnetism and antiferromagnetic spintronics.


  
Securin-independent regulation of separase by checkpoint-induced shugoshin-MAD2 期刊论文
NATURE, 2020, 580 (7804) : 536-+
作者:  Redhai, Siamak;  Pilgrim, Clare;  Gaspar, Pedro;  van Giesen, Lena;  Lopes, Tatiana;  Riabinina, Olena;  Grenier, Theodore;  Milona, Alexandra;  Chanana, Bhavna;  Swadling, Jacob B.;  Wang, Yi-Fang;  Dahalan, Farah;  Yuan, Michaela;  Wilsch-Brauninger, Michaela;  Lin, Wei-hsiang;  Dennison, Nathan;  Capriotti, Paolo;  Lawniczak, Mara K. N.;  Baines, Richard A.;  Warnecke, Tobias;  Windbichler, Nikolai;  Leulier, Francois;  Bellono, Nicholas W.;  Miguel-Aliaga, Irene
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/03

Shugoshin and MAD2 regulate separase-mediated chromosome separation during mitosis, in parallel to a previously identified mechanism involving the anaphase inhibitor securin.


Separation of eukaryotic sister chromatids during the cell cycle is timed by the spindle assembly checkpoint (SAC) and ultimately triggered when separase cleaves cohesion-mediating cohesin(1-3). Silencing of the SAC during metaphase activates the ubiquitin ligase APC/C (anaphase-promoting complex, also known as the cyclosome) and results in the proteasomal destruction of the separase inhibitor securin(1). In the absence of securin, mammalian chromosomes still segregate on schedule, but it is unclear how separase is regulated under these conditions(4,5). Here we show that human shugoshin 2 (SGO2), an essential protector of meiotic cohesin with unknown functions in the soma(6,7), is turned into a separase inhibitor upon association with SAC-activated MAD2. SGO2-MAD2 can functionally replace securin and sequesters most separase in securin-knockout cells. Acute loss of securin and SGO2, but not of either protein individually, resulted in separase deregulation associated with premature cohesin cleavage and cytotoxicity. Similar to securin(8,9), SGO2 is a competitive inhibitor that uses a pseudo-substrate sequence to block the active site of separase. APC/C-dependent ubiquitylation and action of the AAA-ATPase TRIP13 in conjunction with the MAD2-specific adaptor p31(comet) liberate separase from SGO2-MAD2 in vitro. The latter mechanism facilitates a considerable degree of sister chromatid separation in securin-knockout cells that lack APC/C activity. Thus, our results identify an unexpected function of SGO2 in mitotically dividing cells and a mechanism of separase regulation that is independent of securin but still supervised by the SAC.