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Breaking Earth's shell into a global plate network 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Tang, C. A.;  Webb, A. A. G.;  Moore, W. B.;  Wang, Y. Y.;  Ma, T. H.;  Chen, T. T.
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/21
Gainers and losers of surface and terrestrial water resources in China during 1989-2016 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Wang, Xinxin;  Xiao, Xiangming;  Zou, Zhenhua;  Dong, Jinwei;  Qin, Yuanwei;  Doughty, Russell B.;  Menarguez, Michael A.;  Chen, Bangqian;  Wang, Junbang;  Ye, Hui;  Ma, Jun;  Zhong, Qiaoyan;  Zhao, Bin;  Li, Bo
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/14
Constraining remote oxidation capacity with ATom observations 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (13) : 7753-7781
作者:  Travis, Katherine R.;  Heald, Colette L.;  Allen, Hannah M.;  Apel, Eric C.;  Arnold, Stephen R.;  Blake, Donald R.;  Brune, William H.;  Chen, Xin;  Commane, Roisin;  Crounse, John D.;  Daube, Bruce C.;  Diskin, Glenn S.;  Elkins, James W.;  Evans, Mathew J.;  Hall, Samuel R.;  Hintsa, Eric J.;  Hornbrook, Rebecca S.;  Kasibhatla, Prasad S.;  Kim, Michelle J.;  Luo, Gan;  McKain, Kathryn;  Millet, Dylan B.;  Moore, Fred L.;  Peischl, Jeffrey;  Ryerson, Thomas B.;  Sherwen, Tomas;  Thames, Alexander B.;  Ullmann, Kirk;  Wang, Xuan;  Wennberg, Paul O.;  Wolfe, Glenn M.;  Yu, Fangqun
收藏  |  浏览/下载:48/0  |  提交时间:2020/08/18
Rapidly-migrating and internally-generated knickpoints can control submarine channel evolution 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Heijnen, Maarten S.;  Clare, Michael A.;  Cartigny, Matthieu J. B.;  Talling, Peter J.;  Hage, Sophie;  Lintern, D. Gwyn;  Stacey, Cooper;  Parsons, Daniel R.;  Simmons, Stephen M.;  Chen, Ye;  Sumner, Esther J.;  Dix, Justin K.;  Clarke, John E. Hughes
收藏  |  浏览/下载:13/0  |  提交时间:2020/06/22
An encrusting kleptoparasite-host interaction from the early Cambrian 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Zhang, Zhifei;  Strotz, Luke C.;  Topper, Timothy P.;  Chen, Feiyang;  Chen, Yanlong;  Liang, Yue;  Zhang, Zhiliang;  Skovsted, Christian B.;  Brock, Glenn A.
收藏  |  浏览/下载:9/0  |  提交时间:2020/06/09
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease 期刊论文
NATURE, 2020, 577 (7790) : 399-+
作者:  Gate, David;  Saligrama, Naresha;  Leventhal, Olivia;  Yang, Andrew C.;  Unger, Michael S.;  Middeldorp, Jinte;  Chen, Kelly;  Lehallier, Benoit;  Channappa, Divya;  De Los Santos, Mark B.;  McBride, Alisha;  Pluvinage, John;  Elahi, Fanny;  Tam, Grace Kyin-Ye;  Kim, Yongha;  Greicius, Michael;  Wagner, Anthony D.;  Aigner, Ludwig;  Galasko, Douglas R.;  Davis, Mark M.;  Wyss-Coray, Tony
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/03

Alzheimer'  s disease is an incurable neurodegenerative disorder in which neuroinflammation has a critical function(1). However, little is known about the contribution of the adaptive immune response in Alzheimer'  s disease(2). Here, using integrated analyses of multiple cohorts, we identify peripheral and central adaptive immune changes in Alzheimer'  s disease. First, we performed mass cytometry of peripheral blood mononuclear cells and discovered an immune signature of Alzheimer'  s disease that consists of increased numbers of CD8(+) T effector memory CD45RA(+) (T-EMRA) cells. In a second cohort, we found that CD8(+) T-EMRA cells were negatively associated with cognition. Furthermore, single-cell RNA sequencing revealed that T cell receptor (TCR) signalling was enhanced in these cells. Notably, by using several strategies of single-cell TCR sequencing in a third cohort, we discovered clonally expanded CD8(+) T-EMRA cells in the cerebrospinal fluid of patients with Alzheimer'  s disease. Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with Alzheimer'  s disease to two separate Epstein-Barr virus antigens. These results reveal an adaptive immune response in the blood and cerebrospinal fluid in Alzheimer'  s disease and provide evidence of clonal, antigen-experienced T cells patrolling the intrathecal space of brains affected by age-related neurodegeneration.


  
Global Model of Whistler Mode Chorus in the Near-Equatorial Region (|lambda(m)|< 18 degrees) 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (11)
作者:  Meredith, Nigel P.;  Horne, Richard B.;  Shen, Xiao-Chen;  Li, Wen;  Bortnik, Jacob
收藏  |  浏览/下载:9/0  |  提交时间:2020/05/25
whistler mode chorus  wave-particle interactions  radiation belts  
Particle-in-Cell Simulation of Electron Cyclotron Harmonic Waves Driven by a Loss Cone Distribution 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (9)
作者:  Wu, Yifan;  Tao, Xin;  Liu, Xu;  Chen, Lunjin;  Xie, Huasheng;  Liu, Kaijun;  Horne, Richard B.
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/02
ECH waves  PIC simulation  magnetosphere  electrostatic wave  loss cone distribution  
Late-spring frost risk between 1959 and 2017 decreased in North America but increased in Europe and Asia 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (22) : 12192-12200
作者:  Zohner, Constantin M.;  Mo, Lidong;  Renner, Susanne S.;  Svenning, Jens-Christian;  Vitasse, Yann;  Benito, Blas M.;  Ordonez, Alejandro;  Baumgarten, Frederik;  Bastin, Jean-Francois;  Sebald, Veronica;  Reich, Peter B.;  Liang, Jingjing;  Nabuurs, Gert-Jan;  de-Miguel, Sergio;  Alberti, Giorgio;  Anton-Fernandez, Clara;  Balazy, Radomir;  Braendli, Urs-Beat;  Chen, Han Y. H.;  Chisholm, Chelsea;  Cienciala, Emil;  Dayanandan, Selvadurai;  Fayle, Tom M.;  Frizzera, Lorenzo;  Gianelle, Damiano;  Jagodzinski, Andrzej M.;  Jaroszewicz, Bogdan;  Jucker, Tommaso;  Kepfer-Rojas, Sebastian;  Khan, Mohammed Latif;  Kim, Hyun Seok;  Korjus, Henn;  Johannsen, Vivian Kvist;  Laarmann, Diana;  Lang, Mait;  Zawila-Niedzwiecki, Tomasz;  Niklaus, Pascal A.;  Paquette, Alain;  Pretzsch, Hans;  Saikia, Purabi;  Schall, Peter;  Seben, Vladimir;  Svoboda, Miroslav;  Tikhonova, Elena;  Viana, Helder;  Zhang, Chunyu;  Zhao, Xiuhai;  Crowther, Thomas W.
收藏  |  浏览/下载:19/0  |  提交时间:2020/05/13
climate change  phenology  spring leaf-out  late frost  freezing damage  
Increasing contribution of peatlands to boreal evapotranspiration in a warming climate 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (6) : 555-+
作者:  Helbig, Manuel;  Waddington, James Michael;  Alekseychik, Pavel;  Amiro, Brian D.;  Aurela, Mika;  Barr, Alan G.;  Black, T. Andrew;  Blanken, Peter D.;  Carey, Sean K.;  Chen, Jiquan;  Chi, Jinshu;  Desai, Ankur R.;  Dunn, Allison;  Euskirchen, Eugenie S.;  Flanagan, Lawrence B.;  Forbrich, Inke;  Friborg, Thomas;  Grelle, Achim;  Harder, Silvie;  Heliasz, Michal;  Humphreys, Elyn R.;  Ikawa, Hiroki;  Isabelle, Pierre-Erik;  Iwata, Hiroki;  Jassal, Rachhpal;  Korkiakoski, Mika;  Kurbatova, Juliya;  Kutzbach, Lars;  Lindroth, Anders;  Lofvenius, Mikaell Ottosson;  Lohila, Annalea;  Mammarella, Ivan;  Marsh, Philip;  Maximov, Trofim;  Melton, Joe R.;  Moore, Paul A.;  Nadeau, Daniel F.;  Nicholls, Erin M.;  Nilsson, Mats B.;  Ohta, Takeshi;  Peichl, Matthias;  Petrone, Richard M.;  Petrov, Roman;  Prokushkin, Anatoly;  Quinton, William L.;  Reed, David E.;  Roulet, Nigel T.;  Runkle, Benjamin R. K.;  Sonnentag, Oliver;  Strachan, Ian B.;  Taillardat, Pierre;  Tuittila, Eeva-Stiina;  Tuovinen, Juha-Pekka;  Turner, Jessica;  Ueyama, Masahito;  Varlagin, Andrej;  Wilmking, Martin;  Wofsy, Steven C.;  Zyrianov, Vyacheslav
收藏  |  浏览/下载:14/0  |  提交时间:2020/05/13