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The Magnetic Fabric of Gouge Mimics the Co‐seismic Focal Mechanism of the Chi‐Chi Earthquake (1999, Mw 7.6) 期刊论文
Geophysical Research Letters, 2020
作者:  Yu‐;  Min Chou;  Charles Aubourg;  En‐;  Chao Yeh;  Sheng‐;  Rong Song;  Yi‐;  Kai Lin;  Fabien Humbert;  Xiaodong Jiang;  Teh‐;  Quei Lee
收藏  |  浏览/下载:10/0  |  提交时间:2020/10/26
Splitting Dynamics of Liquid Slugs at a T‐Junction 期刊论文
Water Resources Research, 2020
作者:  Song Xue;  Zhibing Yang;  Ran Hu;  Yi‐;  Feng Chen
收藏  |  浏览/下载:5/0  |  提交时间:2020/08/09
Recent anthropogenic curtailing of Yellow River runoff and sediment load is unprecedented over the past 500 y 期刊论文
Proceedings of the National Academy of Science, 2020
作者:  Yu Liu;  Huiming Song;  Zhisheng An;  Changfeng Sun;  Valerie Trouet;  Qiufang Cai;  Ruoshi Liu;  Steven W. Leavitt;  Yi Song;  Qiang Li;  Congxi Fang;  Weijian Zhou;  Yinke Yang;  Zhao Jin;  Yunqiang Wang;  Junyan Sun;  Xingmin Mu;  Ying Lei;  Lu Wang;  Xuxiang Li;  Meng Ren;  Linlin Cui;  Xueli Zeng
收藏  |  浏览/下载:11/0  |  提交时间:2020/08/09
Why does the CP El Niño less frequently evolve into La Niña than the EP El Niño? 期刊论文
Geophysical Research Letters, 2020
作者:  Shan He;  Jin‐;  Yi Yu;  Song Yang;  Shih‐;  Wei Fang
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/14
Fine Particulate Matter and Poor Cognitive Function among Chinese Older Adults: Evidence from a Community-Based, 12-Year Prospective Cohort Study 期刊论文
Environmental Health Perspectives, 2020
作者:  Jiaonan Wang;  Tiantian Li;  Yuebin Lv;  Virginia Byers Kraus;  Yi Zhang;  Chen Mao;  Zhaoxue Yin;  Wanying Shi;  Jinhui Zhou;  Tongzhang Zheng;  Patrick L. Kinney;  John Ji;  Song Tang;  Xiaoming Shi
收藏  |  浏览/下载:12/0  |  提交时间:2020/06/22
A precise polyrotaxane synthesizer 期刊论文
Science, 2020
作者:  Yunyan Qiu;  Bo Song;  Cristian Pezzato;  Dengke Shen;  Wenqi Liu;  Long Zhang;  Yuanning Feng;  Qing-Hui Guo;  Kang Cai;  Weixingyue Li;  Hongliang Chen;  Minh T. Nguyen;  Yi Shi;  Chuyang Cheng;  R. Dean Astumian;  Xiaopeng Li;  J. Fraser Stoddart
收藏  |  浏览/下载:15/0  |  提交时间:2020/06/16
Spatial Variation of Reactive Nitrogen Emissions From China's Croplands Codetermined by Regional Urbanization and Its Feedback to Global Climate Change 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (12)
作者:  Xu, Peng;  Chen, Anping;  Houlton, Benjamin Z.;  Zeng, Zhenzhong;  Wei, Song;  Zhao, Chenxu;  Lu, Haiyan;  Liao, Yajun;  Zheng, Zhonghua;  Luan, Shengji;  Zheng, Yi
收藏  |  浏览/下载:15/0  |  提交时间:2020/06/01
reactive gaseous nitrogen  agricultural soils  emission inventory  urbanization  climate change impacts  
Structure and mechanism of human diacylglycerol O-acyltransferase 1 期刊论文
NATURE, 2020, 581 (7808) : 329-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/03

The structure of human diacylglycerol O-acyltransferase 1, a membrane protein that synthesizes triacylglycerides, is solved with cryo-electron microscopy, providing insight into its function and mechanism of enzymatic activity.


Diacylglycerol O-acyltransferase 1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans(1). DGAT1 belongs to the membrane-bound O-acyltransferase (MBOAT) superfamily, members of which are found in all kingdoms of life and are involved in the acylation of lipids and proteins(2,3). How human DGAT1 and other mammalian members of the MBOAT family recognize their substrates and catalyse their reactions is unknown. The absence of three-dimensional structures also hampers rational targeting of DGAT1 for therapeutic purposes. Here we present the cryo-electron microscopy structure of human DGAT1 in complex with an oleoyl-CoA substrate. Each DGAT1 protomer has nine transmembrane helices, eight of which form a conserved structural fold that we name the MBOAT fold. The MBOAT fold in DGAT1 forms a hollow chamber in the membrane that encloses highly conserved catalytic residues. The chamber has separate entrances for each of the two substrates, fatty acyl-CoA and diacylglycerol. DGAT1 can exist as either a homodimer or a homotetramer and the two forms have similar enzymatic activity. The N terminus of DGAT1 interacts with the neighbouring protomer and these interactions are required for enzymatic activity.


  
The online competition between pro- and anti-vaccination views 期刊论文
NATURE, 2020, 582 (7811) : 230-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

Insights into the interactions between pro- and anti-vaccination clusters on Facebook can enable policies and approaches that attempt to interrupt the shift to anti-vaccination views and persuade undecided individuals to adopt a pro-vaccination stance.


Distrust in scientific expertise(1-14) is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks(2-4), as happened for measles in 2019(5,6). Homemade remedies(7,8) and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice(9-11). There is a lack of understanding about how this distrust evolves at the system level(13,14). Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change(11), and highlight the key role of network cluster dynamics in multi-species ecologies(15).


  
Combined Scattering of Radiation Belt Electrons by Low-Frequency Hiss: Cyclotron, Landau, and Bounce Resonances 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (5)
作者:  Fu, Song;  Yi, Juan;  Ni, Binbin;  Zhou, Ruoxian;  Hu, Zejun;  Cao, Xing;  Gu, Xudong;  Guo, Deyu
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/02