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Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants 期刊论文
Science, 2020
作者:  Siwei Zhang;  Hanwen Zhang;  Yifan Zhou;  Min Qiao;  Siming Zhao;  Alena Kozlova;  Jianxin Shi;  Alan R. Sanders;  Gao Wang;  Kaixuan Luo;  Subhajit Sengupta;  Siobhan West;  Sheng Qian;  Michael Streit;  Dimitrios Avramopoulos;  Chad A. Cowan;  Mengjie Chen;  Zhiping P. Pang;  Pablo V. Gejman;  Xin He;  Jubao Duan
收藏  |  浏览/下载:10/0  |  提交时间:2020/08/09
Formation of liquid-like cellular organelles depends on their composition 期刊论文
NATURE, 2020, 581 (7807) : 144-145
作者:  Sengupta, Partho P.;  Adjeroh, Donald A.
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/03

Phase separation of the nucleolus is composition dependent.


Liquid-like organelles in cells form when key constituents reach a certain concentration and then condense. Evidence now indicates that the concentration at which condensation occurs can vary, contrary to previous assumptions.