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A comprehensive quantification of global nitrous oxide sources and sinks 期刊论文
Nature, 2020
作者:  Hanqin Tian;  Rongting Xu;  Josep G. Canadell;  Rona L. Thompson;  Wilfried Winiwarter;  Parvadha Suntharalingam;  Eric A. Davidson;  Philippe Ciais;  Robert B. Jackson;  Greet Janssens-Maenhout;  Michael J. Prather;  Pierre Regnier;  Naiqing Pan;  Shufen Pan;  Glen P. Peters;  Hao Shi;  Francesco N. Tubiello;  ;  nke Zaehle;  Feng Zhou;  Almut Arneth;  Gianna Battaglia;  Sarah Berthet;  Laurent Bopp;  Alexander F. Bouwman;  Erik T. Buitenhuis;  Jinfeng Chang;  Martyn P. Chipperfield;  Shree R. S. Dangal;  Edward Dlugokencky;  James W. Elkins;  Bradley D. Eyre;  Bojie Fu;  Bradley Hall;  Akihiko Ito;  Fortunat Joos;  Paul B. Krummel;  Angela Landolfi;  Goulven G. Laruelle;  Ronny Lauerwald;  Wei Li;  Sebastian Lienert;  Taylor Maavara;  Michael MacLeod;  Dylan B. Millet;  Stefan Olin;  Prabir K. Patra;  Ronald G. Prinn;  Peter A. Raymond;  Daniel J. Ruiz;  Guido R. van der Werf;  Nicolas Vuichard;  Junjie Wang;  Ray F. Weiss;  Kelley C. Wells;  Chris Wilson;  Jia Yang;  Yuanzhi Yao
收藏  |  浏览/下载:23/0  |  提交时间:2020/10/12
New Guinea has the world鈥檚 richest island flora 期刊论文
Nature, 2020
作者:  Rodrigo Cá;  mara-Leret;  David G. Frodin;  Frits Adema;  Christiane Anderson;  Marc S. Appelhans;  George Argent;  Susana Arias Guerrero;  Peter Ashton;  William J. Baker;  Anders S. Barfod;  David Barrington;  Renata Borosova;  Gemma L. C. Bramley;  Marie Briggs;  Sven Buerki;  Daniel Cahen;  Martin W. Callmander;  Martin Cheek;  Cheng-Wei Chen;  Barry J. Conn;  Mark J. E. Coode;  Iain Darbyshire;  Sally Dawson;  John Dransfield;  Clare Drinkell;  Brigitta Duyfjes;  Atsushi Ebihara;  Zacky Ezedin;  Long-Fei Fu;  Osia Gideon;  Deden Girmansyah;  Rafaë;  l Govaerts;  Helen Fortune-Hopkins;  Gustavo Hassemer;  Alistair Hay;  Charlie D. Heatubun;  D. J. Nicholas Hind;  Peter Hoch;  Peter Homot;  Peter Hovenkamp;  Mark Hughes;  Matthew Jebb;  Laura Jennings;  Tiberius Jimbo;  Michael Kessler;  Ruth Kiew;  Sandra Knapp;  Penniel Lamei;  Marcus Lehnert;  Gwilym P. Lewis;  Hans Peter Linder;  Stuart Lindsay;  Yee Wen Low;  Eve Lucas;  Jeffrey P. Mancera;  Alexandre K. Monro;  Alison Moore;  David J. Middleton;  Hidetoshi Nagamasu;  Mark F. Newman;  Eimear Nic Lughadha;  Pablo H. A. Melo;  Daniel J. Ohlsen;  Caroline M. Pannell;  Barbara Parris;  Laura Pearce;  Darin S. Penneys;  Leon R. Perrie;  Peter Petoe;  Axel Dalberg Poulsen;  Ghillean T. Prance;  J. Peter Quakenbush;  Niels Raes;  Michele Rodda;  Zachary S. Rogers;  André;  Schuiteman;  Pedro Schwartsburd;  Robert W. Scotland;  Mark P. Simmons;  David A. Simpson;  Peter Stevens;  Michael Sundue;  Weston Testo;  Anna Trias-Blasi;  Ian Turner;  Timothy Utteridge;  Lesley Walsingham;  Bruce L. Webber;  Ran Wei;  George D. Weiblen;  Maximilian Weigend;  Peter Weston;  Willem de Wilde;  Peter Wilkie;  Christine M. Wilmot-Dear;  Hannah P. Wilson;  John R. I. Wood;  Li-Bing Zhang;  Peter C. van Welzen
收藏  |  浏览/下载:32/0  |  提交时间:2020/08/18
Atmospheric Evolution of Emissions from a Boreal Forest Fire: The Formation of Highly-Functionalized Oxygen-, Nitrogen-, and Sulfur-Containing Compounds 期刊论文
Atmospheric Chemistry and Physics, 2020
作者:  Jenna C. Ditto, Megan He, Tori N. Hass-Mitchell, Samar G. Moussa, Katherine Hayden, Shao-Meng Li, John Liggio, Amy Leithead, Patrick Lee, Michael J. Wheeler, Jeremy J. B. Wenztell, and Drew R. Gentner
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/09
Enhanced growth rate of atmospheric particles from sulfuric acid 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (12) : 7359-7372
作者:  Stolzenburg, Dominik;  Simon, Mario;  Ranjithkumar, Ananth;  Kuerten, Andreas;  Lehtipalo, Katrianne;  Gordon, Hamish;  Ehrhart, Sebastian;  Finkenzeller, Henning;  Pichelstorfer, Lukas;  Nieminen, Tuomo;  He, Xu-Cheng;  Brilke, Sophia;  Xiao, Mao;  Amorim, Antonio;  Baalbaki, Rima;  Baccarini, Andrea;  Beck, Lisa;  Brakling, Steffen;  Murillo, Lucia Caudillo;  Chen, Dexian;  Chu, Biwu;  Dada, Lubna;  Dias, Antonio;  Dommen, Josef;  Duplissy, Jonathan;  El Haddad, Imad;  Fischer, Lukas;  Carracedo, Loic Gonzalez;  Heinritzi, Martin;  Kim, Changhyuk;  Koenig, Theodore K.;  Kong, Weimeng;  Lamkaddam, Houssni;  Lee, Chuan Ping;  Leiminger, Markus;  Li, Zijun;  Makhmutov, Vladimir;  Manninen, Hanna E.;  Marie, Guillaume;  Marten, Ruby;  Mueller, Tatjana;  Nie, Wei;  Partoll, Eva;  Petaja, Tuukka;  Pfeifer, Joschka;  Philippov, Maxim;  Rissanen, Matti P.;  Rorup, Birte;  Schobesberger, Siegfried;  Schuchmann, Simone;  Shen, Jiali;  Sipila, Mikko;  Steiner, Gerhard;  Stozhkov, Yuri;  Tauber, Christian;  Tham, Yee Jun;  Tome, Antonio;  Vazquez-Pufleau, Miguel;  Wagner, Andrea C.;  Wang, Mingyi;  Wang, Yonghong;  Weber, Stefan K.;  Wimmer, Daniela;  Wlasits, Peter J.;  Wu, Yusheng;  Ye, Qing;  Zauner-Wieczorek, Marcel;  Baltensperger, Urs;  Carslaw, Kenneth S.;  Curtius, Joachim;  Donahue, Neil M.;  Flagan, Richard C.;  Hansel, Armin;  Kulmala, Markku;  Lelieveld, Jos;  Volkamer, Rainer;  Kirkby, Jasper;  Winkler, Paul M.
收藏  |  浏览/下载:24/0  |  提交时间:2020/08/18
Distinct aerosol effects on cloud-to-ground lightning in the plateau and basin regions of Sichuan, Southwest China 期刊论文
Atmospheric Chemistry and Physics, 2020
作者:  Pengguo Zhao, Zhanqing Li, Hui Xiao, Fang Wu, Youtong Zheng, Maureen C. Cribb, Xiaoai Jin, and Yunjun Zhou
收藏  |  浏览/下载:6/0  |  提交时间:2020/06/22
CORONAVIRUS TESTS GO UNUSED IN THEIR THOUSANDS 期刊论文
NATURE, 2020, 580 (7803) : 312-313
作者:  Slabicki, Mikolaj;  Kozicka, Zuzanna;  Petzold, Georg;  Li, Yen-Der;  Manojkumar, Manisha;  Bunker, Richard D.;  Donovan, Katherine A.;  Sievers, Quinlan L.;  Koeppel, Jonas;  Suchyta, Dakota;  Sperling, Adam S.;  Fink, Emma C.;  Gasser, Jessica A.;  Wang, Li R.
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03
WHY POLLUTION IS FALLING IN SOME CITIES - BUT NOT OTHERS 期刊论文
NATURE, 2020, 580 (7803) : 313-313
作者:  Sulkowski, Parker L.;  Oeck, Sebastian;  Dow, Jonathan;  Economos, Nicholas G.;  Mirfakhraie, Lily;  Liu, Yanfeng;  Noronha, Katelyn;  Bao, Xun;  Li, Jing;  Shuch, Brian M.;  King, Megan C.;  Bindra, Ranjit S.;  Glazer, Peter M.
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/03
Revealing enigmatic mucus structures in the deep sea using DeepPIV 期刊论文
NATURE, 2020, 583 (7814) : 78-+
作者:  Nguyen, Ngoc Uyen Nhi;  Canseco, Diana C.;  Xiao, Feng;  Nakada, Yuji;  Li, Shujuan;  Lam, Nicholas T.;  Muralidhar, Shalini A.;  Savla, Jainy J.;  Hill, Joseph A.;  Le, Victor;  Zidan, Kareem A.;  El-Feky, Hamed W.;  Wang, Zhaoning;  Ahmed, Mahmoud Salama;  Hubbi, Maimon E.;  Menendez-Montes, Ivan
收藏  |  浏览/下载:13/0  |  提交时间:2020/06/09

Advanced deep-sea imaging tools yield insights into the structure and function of mucus filtration houses built by midwater giant larvaceans.


Many animals build complex structures to aid in their survival, but very few are built exclusively from materials that animals create (1,2). In the midwaters of the ocean, mucoid structures are readily secreted by numerous animals, and serve many vital functions(3,4). However, little is known about these mucoid structures owing to the challenges of observing them in the deep sea. Among these mucoid forms, the '  houses'  of larvaceans are marvels of nature(5), and in the ocean twilight zone giant larvaceans secrete and build mucus filtering structures that can reach diameters of more than 1 m(6). Here we describe in situ laser-imaging technology(7) that reconstructs three-dimensional models of mucus forms. The models provide high-resolution views of giant larvacean houses and elucidate the role that house structure has in food capture and predator avoidance. Now that tools exist to study mucus structures found throughout the ocean, we can shed light on some of nature'  s most complex forms.


  
In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer (vol 575, pg 380, 2019) 期刊论文
NATURE, 2020, 577 (7791) : E7-E7
作者:  Momcilovic, Milica;  Jones, Anthony;  Bailey, Sean T.;  Waldmann, Christopher M.;  Li, Rui;  Lee, Jason T.;  Abdelhady, Gihad;  Gomez, Adrian;  Holloway, Travis;  Schmid, Ernst;  Stout, David;  Fishbein, Michael C.;  Stiles, Linsey;  Dabir, Deepa V.;  Dubinett, Steven M.;  Christofk, Heather;  Shirihai, Orian;  Koehler, Carla M.;  Sadeghi, Saman;  Shackelford, David B.
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/03
Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease 期刊论文
NATURE, 2020, 577 (7788) : 103-+
作者:  Lalaoui, Najoua;  Boyden, Steven E.;  Oda, Hirotsugu;  Wood, Geryl M.;  Stone, Deborah L.;  Chau, Diep;  Liu, Lin;  Stoffels, Monique;  Kratina, Tobias;  Lawlor, Kate E.;  Zaal, Kristien J. M.;  Hoffmann, Patrycja M.;  Etemadi, Nima;  Shield-Artin, Kristy;  Biben, Christine;  Tsai, Wanxia Li;  Blake, Mary D.;  Kuehn, Hye Sun;  Yang, Dan;  Anderton, Holly;  Silke, Natasha;  Wachsmuth, Laurens;  Zheng, Lixin;  Moura, Natalia Sampaio;  Beck, David B.;  Gutierrez-Cruz, Gustavo;  Ombrello, Amanda K.;  Pinto-Patarroyo, Gineth P.;  Kueh, Andrew J.;  Herold, Marco J.;  Hall, Cathrine;  Wang, Hongying;  Chae, Jae Jin;  Dmitrieva, Natalia I.;  McKenzie, Mark;  Light, Amanda;  Barham, Beverly K.;  Jones, Anne;  Romeo, Tina M.;  Zhou, Qing;  Aksentijevich, Ivona;  Mullikin, James C.;  Gross, Andrew J.;  Shum, Anthony K.;  Hawkins, Edwin D.;  Masters, Seth L.;  Lenardo, Michael J.;  Boehm, Manfred;  Rosenzweig, Sergio D.;  Pasparakis, Manolis;  Voss, Anne K.;  Gadina, Massimo;  Kastner, Daniel L.;  Silke, John
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/03

RIPK1 is a key regulator of innate immune signalling pathways. To ensure an optimal inflammatory response, RIPK1 is regulated post-translationally by well-characterized ubiquitylation and phosphorylation events, as well as by caspase-8-mediated cleavage1-7. The physiological relevance of this cleavage event remains unclear, although it is thought to inhibit activation of RIPK3 and necroptosis8. Here we show that the heterozygous missense mutations D324N, D324H and D324Y prevent caspase cleavage of RIPK1 in humans and result in an early-onset periodic fever syndrome and severe intermittent lymphadenopathy-a condition we term '  cleavage-resistant RIPK1-induced autoinflammatory syndrome'  . To define the mechanism for this disease, we generated a cleavage-resistant Ripk1(D325A) mutant mouse strain. Whereas Ripk1(-/-) mice died postnatally from systemic inflammation, Ripk1(D325A/D325A) mice died during embryogenesis. Embryonic lethality was completely prevented by the combined loss of Casp8 and Ripk3, but not by loss of Ripk3 or Mlkl alone. Loss of RIPK1 kinase activity also prevented Ripk1(D325A/D325A) embryonic lethality, although the mice died before weaning from multi-organ inflammation in a RIPK3-dependent manner. Consistently, Ripk1(D325A/D325A) and Ripk1(D325A/+) cells were hypersensitive to RIPK3-dependent TNF-induced apoptosis and necroptosis. Heterozygous Ripk1(D325A/+) mice were viable and grossly normal, but were hyper-responsive to inflammatory stimuli in vivo. Our results demonstrate the importance of caspase-mediated RIPK1 cleavage during embryonic development and show that caspase cleavage of RIPK1 not only inhibits necroptosis but also maintains inflammatory homeostasis throughout life.