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Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3K alpha inhibitors 期刊论文
SCIENCE, 2019, 366 (6466) : 714-+
作者:  Vasan, Neil;  Razavi, Pedram;  Johnson, Jared L.;  Shao, Hong;  Shah, Hardik;  Antoine, Alesia;  Ladewig, Erik;  Gorelick, Alexander;  Lin, Ting-Yu;  Toska, Eneda;  Xu, Guotai;  Kazmi, Abiha;  Chang, Matthew T.;  Taylor, Barry S.;  Dickler, Maura N.;  Jhaveri, Komal;  Chandarlapaty, Sarat;  Rabadan, Raul;  Reznik, Ed;  Smith, Melissa L.;  Sebra, Robert;  Schimmoller, Frauke;  Wilson, Timothy R.;  Friedman, Lori S.;  Cantley, Lewis C.;  Scaltriti, Maurizio;  Baselga, Jose
收藏  |  浏览/下载：14/0  |  提交时间：2020/02/17
Global modeling of nature's contributions to people 期刊论文
SCIENCE, 2019, 366 (6462) : 255-+
作者:  Chaplin-Kramer, Rebecca;  Sharp, Richard P.;  Weill, Charlotte;  Bennett, Elena M.;  Pascual, Unai;  Arkema, Katie K.;  Brauman, Kate A.;  Bryant, Benjamin P.;  Guerry, Anne D.;  Haddad, Nick M.;  Hamann, Maike;  Hamel, Perrine;  Johnson, Justin A.;  Mandle, Lisa;  Pereira, Henrique M.;  Polasky, Stephen;  Ruckelshaus, Mary;  Rebecca Shaw, M.;  Silver, Jessica M.;  Vogl, Adrian L.;  Daily, Gretchen C.
收藏  |  浏览/下载：11/0  |  提交时间：2019/11/27
A giant exoplanet orbiting a very-low-mass star challenges planet formation models 期刊论文
SCIENCE, 2019, 365 (6460) : 1441-+
作者:  Morales, J. C.;  Mustill, A. J.;  Ribas, I.;  Davies, M. B.;  Reiners, A.;  Bauers, F. F.;  Kossakowski, D.;  Herrero, E.;  Rodriguez, E.;  Lopez-Gonzalez, M. J.;  Rodriguez-Lopez, C.;  Bejar, V. J. S.;  Gonzalez-Cuesta, L.;  Luque, R.;  Palle, E.;  Perger, M.;  Baroch, D.;  Johansen, A.;  Klahr, H.;  Mordasini, C.;  Anglada-Escude, G.;  Caballero, J. A.;  Cortes-Contreras, M.;  Dreizler, S.;  Lafarga, M.;  Nagel, E.;  Passegger, V. M.;  Reffert, S.;  Rosich, A.;  Schweitzer, A.;  Tal-Or, L.;  Trifonov, T.;  Zechmeister, M.;  Quirrenbach, A.;  Amado, P. J.;  Guenther, E. W.;  Hagen, H. -J.;  Henning, T.;  Jeffers, S. V.;  Kaminski, A.;  Kuester, M.;  Montes, D.;  Seifert, W.;  Abellan, F. J.;  Abril, M.;  Aceituno, J.;  Aceituno, F. J.;  Alonso-Floriano, F. J.;  Ammler-von Eiff, M.;  Antona, R.;  Arroyo-Torres, B.;  Azzaro, M.;  Barrado, D.;  Becerril-Jarque, S.;  Benitez, D.;  Berdinas, Z. M.;  Bergond, G.;  Brinkmoller, M.;  del Burgo, C.;  Burn, R.;  Calvo-Ortega, R.;  Cano, J.;  Cardenas, M. C.;  Cardona Guillen, C.;  Carro, J.;  Casa, E.;  Casanova, V.;  Casasayas-Barris, N.;  Chaturvedi, P.;  Cifuentes, C.;  Claret, A.;  Colome, J.;  Czesla, S.;  Diez-Alonso, E.;  Dorda, R.;  Emsenhuber, A.;  Fernandez, M.;  Fernandez-Martin, A.;  Ferro, I. M.;  Fuhrmeister, B.;  Galadi-Enriquez, D.;  Gallardo Cava, I.;  Garcia Vargas, M. L.;  Garcia-Piquer, A.;  Gesa, L.;  Gonzalez-Alvarez, E.;  Gonzalez Hernandez, J. I.;  Gonzalez-Peinado, R.;  Guardia, J.;  Guijarro, A.;  de Guindos, E.;  Hatzes, A. P.;  Hauschildt, P. H.;  Hedrosa, R. P.;  Hermelo, I.;  Hernandez Arabi, R.;  Hernandez Otero, F.;  Hintz, D.;  Holgado, G.;  Huber, A.;  Huke, P.;  Johnson, E. N.;  de Juan, E.;  Kehr, M.;  Kemmer, J.;  Kim, M.;  Klueter, J.;  Klutsch, A.;  Labarga, F.;  Labiche, N.;  Lalitha, S.;  Lampon, M.;  Lara, L. M.;  Launhardt, R.;  Lazaro, F. J.;  Lizon, J. -L.;  Llamas, M.;  Lodieu, N.;  Lopez del Fresno, M.;  Lopez Salas, . F.;  Lopez-Santiago, J.;  Magan Madinabeitia, H.;  Mall, U.;  Mancini, L.;  Mandel, H.;  Marfil, E.;  Marin Molina, J. . A.;  Martin, E. L.;  Martin-Fernandez, P.;  Martin-Ruiz, S.;  Martinez-Rodriguez, H.;  Marvin, C. J.;  Mirabet, E.;  Moya, A.;  Naranjo, V.;  Nelson, R. P.;  Nortmann, L.;  Nowak, G.;  Ofir, A.;  Pascua, J.;  Pavlov, A.;  Pedraz, S.;  Perez Medialdea, D.;  Perez-Calpena, A.;  Perryman, M. A. C.;  Rabaza, O.;  Ramon Ballesta, A.;  Rebolo, R.;  Redondo, P.;  Rix, H. -W.;  Rodler, F.;  Rodriguez Trinidad, A.;  Sabotta, S.;  Sadegi, S.;  Salz, M.;  Sanchez-Blanco, E.;  Sanchez Carrasco, M. A.;  Sanchez-Lopez, A.;  Sanz-Forcada, J.;  Sarkis, P.;  Sarmiento, L. F.;  Schafer, S.;  Schlecker, M.;  Schmitt, J. H. M. M.;  Schofer, P.;  Solano, E.;  Sota, A.;  Stahl, O.;  Stock, S.;  Stuber, T.;  Sturmer, J.;  Suarez, J. C.;  Tabernero, H. M.;  Tulloch, S. M.;  Veredas, G.;  Vico-Linares, J. I.;  Vilardell, F.;  Wagner, K.;  Winkler, J.;  Wolthoff, V.;  Yan, F.;  Zapatero Osorio, M. R.
收藏  |  浏览/下载：16/0  |  提交时间：2019/11/27
Archaeological assessment reveals Earth's early transformation through land use 期刊论文
SCIENCE, 2019, 365 (6456) : 897-+
作者:  Stephens, Lucas;  Fuller, Dorian;  Boivin, Nicole;  Rick, Torben;  Gauthier, Nicolas;  Kay, Andrea;  Marwick, Ben;  Armstrong, Chelsey Geralda Denise;  Barton, C. Michael;  Denham, Tim;  Douglass, Kristina;  Driver, Jonathan;  Janz, Lisa;  Roberts, Patrick;  Rogers, J. Daniel;  Thakar, Heather;  Altaweel, Mark;  Johnson, Amber L.;  Sampietro Vattuone, Maria Marta;  Aldenderfer, Mark;  Archila, Sonia;  Artioli, Gilberto;  Bale, Martin T.;  Beach, Timothy;  Borrell, Ferran;  Braje, Todd;  Buckland, Philip I.;  Jimenez Cano, Nayeli Guadalupe;  Capriles, Jose M.;  Diez Castillo, Agustin;  Cilingiroglu, Ciler;  Cleary, Michelle Negus;  Conolly, James;  Coutros, Peter R.;  Covey, R. Alan;  Cremaschi, Mauro;  Crowther, Alison;  Der, Lindsay;  di Lernia, Savino;  Doershuk, John F.;  Doolittle, William E.;  Edwards, Kevin J.;  Erlandson, Jon M.;  Evans, Damian;  Fairbairn, Andrew;  Faulkner, Patrick;  Feinman, Gary;  Fernandes, Ricardo;  Fitzpatrick, Scott M.;  Fyfe, Ralph;  Garcea, Elena;  Goldstein, Steve;  Goodman, Reed Charles;  Guedes, Jade Dalpoim;  Herrmann, Jason;  Hiscock, Peter;  Hommel, Peter;  Horsburgh, K. Ann;  Hritz, Carrie;  Ives, John W.;  Junno, Aripekka;  Kahn, Jennifer G.;  Kaufman, Brett;  Kearns, Catherine;  Kidder, Tristram R.;  Lanoe, Francois;  Lawrence, Dan;  Lee, Gyoung-Ah;  Levin, Maureece J.;  Lindskoug, Henrik B.;  Antonio Lopez-Saez, Jose;  Macrae, Scott;  Marchant, Rob;  Marston, John M.;  McClure, Sarah;  Mccoy, Mark D.;  Miller, Alicia Ventresca;  Morrison, Michael;  Matuzeviciute, Giedre Motuzaite;  Mueller, Johannes;  Nayak, Ayushi;  Noerwidi, Sofwan;  Peres, Tanya M.;  Peterson, Christian E.;  Proctor, Lucas;  Randall, Asa R.;  Renette, Steve;  Schug, Gwen Robbins;  Ryzewski, Krysta;  Saini, Rakesh;  Scheinsohn, Vivian;  Schmidt, Peter;  Sebillaud, Pauline;  Seitsonen, Oula;  Simpson, Ian A.;  Soltysiak, Arkadiusz;  Speakman, Robert J.;  Spengler, Robert N.;  Steffen, Martina L.;  Storozum, Michael J.;  Strickland, Keir M.;  Thompson, Jessica;  Thurston, T. L.;  Ulm, Sean;  Ustunkaya, M. Cemre;  Welker, Martin H.;  West, Catherine;  Williams, Patrick Ryan;  Wright, David K.;  Wright, Nathan;  Zahir, Muhammad;  Zerboni, Andrea;  Beaudoin, Ella;  Garcia, Santiago Munevar;  Powell, Jeremy;  Thornton, Alexa;  Kaplan, Jed O.;  Gaillard, Marie-Jose;  Goldewijk, Kees Klein;  Ellis, Erle
收藏  |  浏览/下载：56/0  |  提交时间：2019/11/27
N-terminal degradation activates the NLRP1B inflammasome 期刊论文
SCIENCE, 2019, 364 (6435) : 82-+
作者:  Chui, Ashley J.;  Okondo, Marian C.;  Rao, Sahana D.;  Gai, Kuo;  Griswold, Andrew R.;  Johnson, Darren C.;  Ball, Daniel P.;  Taabazuing, Cornelius Y.;  Orth, Elizabeth L.;  Vittimberga, Brooke A.;  Bachovchin, Daniel A.
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
A sea change in our view of overturning in the subpolar North Atlantic 期刊论文
SCIENCE, 2019, 363 (6426) : 516-+
作者:  Lozier, M. S.;  Li, F.;  Bacon, S.;  Bahr, F.;  Bower, A. S.;  Cunningham, S. A.;  de Jong, M. F.;  de Steur, L.;  deYoung, B.;  Fischer, J.;  Gary, S. F.;  Greenan, B. J. W.;  Holliday, N. P.;  Houk, A.;  Houpert, L.;  Inall, M. E.;  Johns, W. E.;  Johnson, H. L.;  Johnson, C.;  Karstensen, J.;  Koman, G.;  Le Bras, I. A.;  Lin, X.;  Mackay, N.;  Marshall, D. P.;  Mercier, H.;  Oltmanns, M.;  Pickart, R. S.;  Ramsey, A. L.;  Rayner, D.;  Straneo, F.;  Thierry, V.;  Torres, D. J.;  Williams, R. G.;  Wilson, C.;  Yang, J.;  Yashayaev, I.;  Zhao, J.
收藏  |  浏览/下载：9/0  |  提交时间：2019/11/27
Chemical interactions between Saturn's atmosphere and its rings 期刊论文
SCIENCE, 2018, 362 (6410) : 51-+
作者:  Waite, J. H., Jr.;  Perryman, R. S.;  Perry, M. E.;  Miller, K. E.;  Bell, J.;  Cravens, T. E.;  Glein, C. R.;  Grimes, J.;  Hedman, M.;  Cuzzi, J.;  Brockwell, T.;  Teolis, B.;  Moore, L.;  Mitchell, D. G.;  Persoon, A.;  Kurth, W. S.;  Wahlund, J. -E.;  Morooka, M.;  Hadid, L. Z.;  Chocron, S.;  Walker, J.;  Nagy, A.;  Yelle, R.;  Ledvina, S.;  Johnson, R.;  Tseng, W.;  Tucker, O. J.;  Ip, W. -H.
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/27
LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis 期刊论文
SCIENCE, 2018, 361 (6400) : 406-411
作者:  Poffenberger, M. C.;  Metcalfe-Roach, A.;  Aguilar, E.;  Chen, J.;  Hsu, B. E.;  Wong, A. H.;  Johnson, R. M.;  Flynn, B.;  Samborska, B.;  Ma, E. H.;  Gravel, S-P;  Tonelli, L.;  Devorkin, L.;  Kim, P.;  Hall, A.;  Izreig, S.;  Loginicheva, E.;  Beauchemin, N.;  Siegel, P. M.;  Artyomov, M. N.;  Lum, J. J.;  Zogopoulos, G.;  Blagih, J.;  Jones, R. G.
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/27
Phase transitions in a programmable quantum spin glass simulator 期刊论文
SCIENCE, 2018, 361 (6398) : 162-165
作者:  Harris, R.;  Sato, Y.;  Berkley, A. J.;  Reis, M.;  Altomare, F.;  Amin, M. H.;  Boothby, K.;  Bunyk, P.;  Deng, C.;  Enderud, C.;  Huang, S.;  Hoskinson, E.;  Johnson, M. W.;  Ladizinsky, E.;  Ladizinsky, N.;  Lanting, T.;  Li, R.;  Medina, T.;  Molavi, R.;  Neufeld, R.;  Oh, T.;  Pavlov, I.;  Perminov, I.;  Poulin-Lamarre, G.;  Rich, C.;  Smirnov, A.;  Swenson, L.;  Tsai, N.;  Volkmann, M.;  Whittaker, J.;  Yao, J.
收藏  |  浏览/下载：11/0  |  提交时间：2019/11/27
Response to Comment on "Plant diversity increases with the strength of negative density dependence at the global scale" 期刊论文
SCIENCE, 2018, 360 (6391)
作者:  LaManna, Joseph A.;  Mangan, Scott A.;  Alonso, Alfonso;  Bourg, Norman A.;  Brockelman, Warren Y.;  Bunyavejchewin, Sarayudh;  Chang, Li-Wan;  Chiang, Jyh-Min;  Chuyong, George B.;  Clay, Keith;  Cordell, Susan;  Davies, Stuart J.;  Furniss, Tucker J.;  Giardina, Christian P.;  Gunatilleke, I. A. U. Nimal;  Gunatilleke, C. V. Savitri;  He, Fangliang;  Howe, Robert W.;  Hubbell, Stephen P.;  Hsieh, Chang-Fu;  Inman-Narahari, Faith M.;  Janik, David;  Johnson, Daniel J.;  Kenfack, David;  Korte, Lisa;  Kral, Kamil;  Larson, Andrew J.;  Lutz, James A.;  McMahon, Sean M.;  McShea, William J.;  Memiaghe, Herve R.;  Nathalang, Anuttara;  Novotny, Vojtech;  Ong, Perry S.;  Orwig, David A.;  Ostertag, Rebecca;  Parker, Geoffrey G.;  Phillips, Richard P.;  Sack, Lawren;  Sun, I-Fang;  Tello, J. Sebastian;  Thomas, Duncan W.;  Turner, Benjamin L.;  Diaz, Dilys M. Vela;  Vrska, Tomas;  Weiblen, George D.;  Wolf, Amy;  Yap, Sandra;  Myers, Jonathan A.
收藏  |  浏览/下载：17/0  |  提交时间：2019/11/27