Global S&T Development Trend Analysis Platform of Resources and Environment
Chromatin, the complex of DNA and protein in cell nuclei, can be modified by ubiquitin molecules. It emerges that this modification occurs in a molecular reaction chamber formed from an enzyme and a scaffold protein.
A phase-separated reaction chamber for chromatin ubiquitination.
Two threads of research in the quest for methods that predict the 3D structures of proteins from their amino-acid sequences have become fully intertwined. The result is a leap forward in the accuracy of predictions.