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Representing the function and sensitivity of coastal interfaces in Earth system models 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Ward, Nicholas D.;  Megonigal, J. Patrick;  Bond-Lamberty, Ben;  Bailey, Vanessa L.;  Butman, David;  Canuel, Elizabeth A.;  Diefenderfer, Heida;  Ganju, Neil K.;  Goni, Miguel A.;  Graham, Emily B.;  Hopkinson, Charles S.;  Khangaonkar, Tarang;  Langley, J. Adam;  McDowell, Nate G.;  Myers-Pigg, Allison N.;  Neumann, Rebecca B.;  Osburn, Christopher L.;  Price, Rene M.;  Rowland, Joel;  Sengupta, Aditi;  Simard, Marc;  Thornton, Peter E.;  Tzortziou, Maria;  Vargas, Rodrigo;  Weisenhorn, Pamela B.;  Windham-Myers, Lisamarie
收藏  |  浏览/下载:13/0  |  提交时间:2020/05/20
Increasing contribution of peatlands to boreal evapotranspiration in a warming climate 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (6) : 555-+
作者:  Helbig, Manuel;  Waddington, James Michael;  Alekseychik, Pavel;  Amiro, Brian D.;  Aurela, Mika;  Barr, Alan G.;  Black, T. Andrew;  Blanken, Peter D.;  Carey, Sean K.;  Chen, Jiquan;  Chi, Jinshu;  Desai, Ankur R.;  Dunn, Allison;  Euskirchen, Eugenie S.;  Flanagan, Lawrence B.;  Forbrich, Inke;  Friborg, Thomas;  Grelle, Achim;  Harder, Silvie;  Heliasz, Michal;  Humphreys, Elyn R.;  Ikawa, Hiroki;  Isabelle, Pierre-Erik;  Iwata, Hiroki;  Jassal, Rachhpal;  Korkiakoski, Mika;  Kurbatova, Juliya;  Kutzbach, Lars;  Lindroth, Anders;  Lofvenius, Mikaell Ottosson;  Lohila, Annalea;  Mammarella, Ivan;  Marsh, Philip;  Maximov, Trofim;  Melton, Joe R.;  Moore, Paul A.;  Nadeau, Daniel F.;  Nicholls, Erin M.;  Nilsson, Mats B.;  Ohta, Takeshi;  Peichl, Matthias;  Petrone, Richard M.;  Petrov, Roman;  Prokushkin, Anatoly;  Quinton, William L.;  Reed, David E.;  Roulet, Nigel T.;  Runkle, Benjamin R. K.;  Sonnentag, Oliver;  Strachan, Ian B.;  Taillardat, Pierre;  Tuittila, Eeva-Stiina;  Tuovinen, Juha-Pekka;  Turner, Jessica;  Ueyama, Masahito;  Varlagin, Andrej;  Wilmking, Martin;  Wofsy, Steven C.;  Zyrianov, Vyacheslav
收藏  |  浏览/下载:17/0  |  提交时间:2020/05/13
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载:39/0  |  提交时间:2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Programmed cell removal by calreticulin in tissue homeostasis and cancer 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Feng, Mingye;  Marjon, Kristopher D.;  Zhu, Fangfang;  Weissman-Tsukamoto, Rachel;  Levett, Aaron;  Sullivan, Katie;  Kao, Kevin S.;  Markovic, Maxim;  Bump, Paul A.;  Jackson, Hannah M.;  Choi, Timothy S.;  Chen, Jing;  Banuelos, Allison M.;  Liu, Jie;  Gip, Phung;  Cheng, Lei;  Wang, Denong;  Weissman, Irving L.
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Benefits of thinning and burning for understory diversity vary with spatial scale and time since treatment 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2018, 419: 58-78
作者:  Rossman, Allison K.;  Halpern, Charles B.;  Harrod, Richy J.;  Urgenson, Lauren S.;  Peterson, David W.;  Bakker, Jonathan D.
收藏  |  浏览/下载:7/0  |  提交时间:2019/04/09
Dry forests  Ecological restoration  Fuel-reduction treatments  Long-term studies  Prescribed burning  Species richness  
Closed-loop stimulation of temporal cortex rescues functional networks and improves memory 期刊论文
NATURE COMMUNICATIONS, 2018, 9
作者:  Ezzyat, Youssef;  Wanda, Paul A.;  Levy, Deborah F.;  Kadel, Allison;  Aka, Ada;  Pedisich, Isaac;  Sperling, Michael R.;  Sharan, Ashwini D.;  Lega, Bradley C.;  Burks, Alexis;  Gross, Robert E.;  Inman, Cory S.;  Jobst, Barbara C.;  Gorenstein, Mark A.;  Davis, Kathryn A.;  Worrell, Gregory A.;  Kucewicz, Michal T.;  Stein, Joel M.;  Gorniak, Richard;  Das, Sandhitsu R.;  Rizzuto, Daniel S.;  Kahana, Michael J.
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients 期刊论文
SCIENCE, 2018, 359 (6371) : 97-103
作者:  Gopalakrishnan, V.;  Spencer, C. N.;  Nezi, L.;  Reuben, A.;  Andrews, M. C.;  Karpinets, T. V.;  Prieto, P. A.;  Vicente, D.;  Hoffman, K.;  Wei, S. C.;  Cogdill, A. P.;  Zhao, L.;  Hudgens, C. W.;  Hutchinson, D. S.;  Manzo, T.;  de Macedo, M. Petaccia;  Cotechini, T.;  Kumar, T.;  Chen, W. S.;  Reddy, S. M.;  Sloane, R. Szczepaniak;  Galloway-Pena, J.;  Jiang, H.;  Chen, P. L.;  Shpall, E. J.;  Rezvani, K.;  Alousi, A. M.;  Chemaly, R. F.;  Shelburne, S.;  Vence, L. M.;  Okhuysen, P. C.;  Jensen, V. B.;  Swennes, A. G.;  McAllister, F.;  Sanchez, E. Marcelo Riquelme;  Zhang, Y.;  Le Chatelier, E.;  Zitvogel, L.;  Pons, N.;  Austin-Breneman, J. L.;  Haydu, L. E.;  Burton, E. M.;  Gardner, J. M.;  Sirmans, E.;  Hu, J.;  Lazar, A. J.;  Tsujikawa, T.;  Diab, A.;  Tawbi, H.;  Glitza, I. C.;  Hwu, W. J.;  Patel, S. P.;  Woodman, S. E.;  Amaria, R. N.;  Davies, M. A.;  Gershenwald, J. E.;  Hwu, P.;  Lee, J. E.;  Zhang, J.;  Coussens, L. M.;  Cooper, Z. A.;  Futreal, P. A.;  Daniel, C. R.;  Ajami, N. J.;  Petrosino, J. F.;  Tetzlaff, M. T.;  Sharma, P.;  Allison, J. P.;  Jenq, R. R.;  Wargo, J. A.
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/27
Illuminating gravitational waves: A concordant picture of photons from a neutron star merger 期刊论文
SCIENCE, 2017, 358 (6370) : 1559-+
作者:  Kasliwal, M. M.;  Nakar, E.;  Singer, L. P.;  Kaplan, D. L.;  Cook, D. O.;  Van Sistine, A.;  Lau, R. M.;  Fremling, C.;  Gottlieb, O.;  Jencson, J. E.;  Adams, S. M.;  Feindt, U.;  Hotokezaka, K.;  Ghosh, S.;  Perley, D. A.;  Yu, P-C.;  Piran, T.;  Allison, J. R.;  Anupama, G. C.;  Balasubramanian, A.;  WBannister, K.;  Bally, J.;  Barnes, J.;  Barway, S.;  Bellm, E.;  Bhalerao, V.;  Bhattacharya, D.;  Blagorodnova, N.;  Bloom, J. S.;  Brady, P. R.;  Cannella, C.;  Chatterjee, D.;  Cenko, S. B.;  Cobb, B. E.;  Copperwheat, C.;  Corsi, A.;  De, K.;  Dobie, D.;  Emery, S. W. K.;  Evans, P. A.;  Fox, O. D.;  Frail, D. A.;  Frohmaier, C.;  Goobar, A.;  Hallinan, G.;  Harrison, F.;  Helou, G.;  Hinderer, T.;  Ho, A. Y. Q.;  Horesh, A.;  Ip, W-H.;  Itoh, R.;  Kasen, D.;  Kim, H.;  Kuin, N. P. M.;  Kupfer, T.;  Lynch, C.;  Madsen, K.;  Mazzali, P. A.;  Miller, A. A.;  Mooley, K.;  Murphy, T.;  Ngeow, C-C.;  Nichols, D.;  Nissanke, S.;  Nugent, P.;  Ofek, E. O.;  Qi, H.;  Quimby, R. M.;  Rosswog, S.;  Rusu, F.;  Sadler, E. M.;  Schmidt, P.;  Sollerman, J.;  Steele, I.;  Williamson, A. R.;  Xu, Y.;  Yan, L.;  Yatsu, Y.;  Zhang, C.;  Zhao, W.
收藏  |  浏览/下载:16/0  |  提交时间:2019/11/27
A radio counterpart to a neutron star merger 期刊论文
SCIENCE, 2017, 358 (6370) : 1579-+
作者:  Hallinan, G.;  Corsi, A.;  Mooley, K. P.;  Hotokezaka, K.;  Nakar, E.;  Kasliwal, M. M.;  Kaplan, D. L.;  Frail, D. A.;  Myers, S. T.;  Murphy, T.;  De, K.;  Dobie, D.;  Allison, J. R.;  Bannister, K. W.;  Bhalerao, V.;  Chandra, P.;  Clarke, T. E.;  Giacintucci, S.;  Ho, A. Y. Q.;  Horesh, A.;  Kassim, N. E.;  Kulkarni, S. R.;  Lenc, E.;  Lockman, F. J.;  Lynch, C.;  Nichols, D.;  Nissanke, S.;  Palliyaguru, N.;  Peters, W. M.;  Piran, T.;  Rana, J.;  Sadler, E. M.;  Singer, L. P.
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
Capturing the Acoustic Radiation Pattern of Strombolian Eruptions using Infrasound Sensors Aboard a Tethered Aerostat, Yasur Volcano, Vanuatu 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2017, 44 (19)
作者:  Jolly, Arthur D.;  Matoza, Robin S.;  Fee, David;  Kennedy, Ben M.;  Lezzi, Alexandra M.;  Fitzgerald, Rebecca H.;  Austin, Allison C.;  Johnson, Richard
收藏  |  浏览/下载:9/0  |  提交时间:2019/04/09