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Decay of Kelvin-Helmholtz Vortices at the Earth's Magnetopause Under Pure Southward IMF Conditions 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (13)
作者:  Nakamura, T. K. M.;  Plaschke, F.;  Hasegawa, H.;  Liu, Y. H.;  Hwang, K. J.;  Blasl, K. A.;  Nakamura, R.
收藏  |  浏览/下载:11/0  |  提交时间:2020/06/22
Kelvin-Helmholtz instability  magnetic reconnection  magnetopause  southward IMF  PIC simulation  turbulence  
Nitrogen and phosphorus constrain the CO2 fertilization of global plant biomass (vol 21, pg 561, 2020) 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (7) : 696-697
作者:  Terrer, Cesar;  Jackson, Robert B.;  Prentice, I. Colin;  Keenan, Trevor F.;  Kaiser, Christina;  Vicca, Sara;  Fisher, Joshua B.;  Reich, Peter B.;  Stocker, Benjamin D.;  Hungate, Bruce A.;  Penuelas, Josep;  McCallum, Ian;  Soudzilovskaia, Nadejda A.;  Cernusak, Lucas A.;  Talhelm, Alan F.;  Van Sundert, Kevin;  Piao, Shilong;  Newton, Paul C. D.;  Hovenden, Mark J.;  Blumenthal, Dana M.;  Liu, Yi Y.;  Mueller, Christoph;  Winter, Klaus;  Field, Christopher B.;  Viechtbauer, Wolfgang;  Van Lissa, Caspar J.;  Hoosbeek, Marcel R.;  Watanabe, Makoto;  Koike, Takayoshi;  Leshyk, Victor O.;  Polley, H. Wayne;  Franklin, Oskar
收藏  |  浏览/下载:31/0  |  提交时间:2020/06/01
Disruption of emergency response to vulnerable populations during floods 期刊论文
NATURE SUSTAINABILITY, 2020
作者:  Yu, Dapeng;  Yin, Jie;  Wilby, Robert L.;  Lane, Stuart N.;  Aerts, Jeroen C. J. H.;  Lin, Ning;  Liu, Min;  Yuan, Hongyong;  Chen, Jianguo;  Prudhomme, Christel;  Guan, Mingfu;  Baruch, Avinoam;  Johnson, Charlie W. D.;  Tule, Xi;  Yu, Lizhong;  Xu, Shiyuan
收藏  |  浏览/下载:19/0  |  提交时间:2020/05/20
Significant methane ebullition from alpine permafrost rivers on the East Qinghai-Tibet Plateau 期刊论文
NATURE GEOSCIENCE, 2020, 13 (5)
作者:  Zhang, Liwei;  Xia, Xinghui;  Liu, Shaoda;  Zhang, Sibo;  Li, Siling;  Wang, Junfeng;  Wang, Gongqin;  Gao, Hui;  Zhang, Zhenrui;  Wang, Qingrui;  Wen, Wu;  Liu, Ran;  Yang, Zhifeng;  Stanley, Emily H.;  Raymond, Peter A.
收藏  |  浏览/下载:11/0  |  提交时间:2020/05/13
A metabolic pathway for bile acid dehydroxylation by the gut microbiome 期刊论文
NATURE, 2020
作者:  Zhong, Miao;  Tran, Kevin;  Min, Yimeng;  Wang, Chuanhao;  Wang, Ziyun;  Dinh, Cao-Thang;  De Luna, Phil;  Yu, Zongqian;  Rasouli, Armin Sedighian;  Brodersen, Peter;  Sun, Song;  Voznyy, Oleksandr;  Tan, Chih-Shan;  Askerka, Mikhail;  Che, Fanglin;  Liu, Min;  Seifitokaldani, Ali;  Pang, Yuanjie;  Lo, Shen-Chuan;  Ip, Alexander;  Ulissi, Zachary;  Sargent, Edward H.
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/03

The biosynthetic pathway that produces the secondary bile acids DCA and LCA in human gut microbes has been fully characterized, engineered into another bacterial host, and used to confer DCA production in germ-free mice-an important proof-of-principle for the engineering of gut microbial pathways.


The gut microbiota synthesize hundreds of molecules, many of which influence host physiology. Among the most abundant metabolites are the secondary bile acids deoxycholic acid (DCA) and lithocholic acid (LCA), which accumulate at concentrations of around 500 mu M and are known to block the growth ofClostridium difficile(1), promote hepatocellular carcinoma(2)and modulate host metabolism via the G-protein-coupled receptor TGR5 (ref.(3)). More broadly, DCA, LCA and their derivatives are major components of the recirculating pool of bile acids(4)  the size and composition of this pool are a target of therapies for primary biliary cholangitis and nonalcoholic steatohepatitis. Nonetheless, despite the clear impact of DCA and LCA on host physiology, an incomplete knowledge of their biosynthetic genes and a lack of genetic tools to enable modification of their native microbial producers limit our ability to modulate secondary bile acid levels in the host. Here we complete the pathway to DCA and LCA by assigning and characterizing enzymes for each of the steps in its reductive arm, revealing a strategy in which the A-B rings of the steroid core are transiently converted into an electron acceptor for two reductive steps carried out by Fe-S flavoenzymes. Using anaerobic in vitro reconstitution, we establish that a set of six enzymes is necessary and sufficient for the eight-step conversion of cholic acid to DCA. We then engineer the pathway intoClostridium sporogenes, conferring production of DCA and LCA on a nonproducing commensal and demonstrating that a microbiome-derived pathway can be expressed and controlled heterologously. These data establish a complete pathway to two central components of the bile acid pool.


  
Noninvasive 2D and 3D Mapping of Root Zone Soil Moisture Through the Detection of Coarse Roots With Ground-Penetrating Radar 期刊论文
WATER RESOURCES RESEARCH, 2020, 56 (5)
作者:  Liu, X.;  Chen, J.;  Butnor, J. R.;  Qin, G.;  Cui, X.;  Fan, B.;  Lin, H.;  Guo, L.
收藏  |  浏览/下载:13/0  |  提交时间:2020/05/13
ecohydrology  in situ  near-surface geophysics  soil mapping  soil-plant-water relationships  subsoil  
Quantifying the Impact of Excess Moisture From Transpiration From Crops on an Extreme Heat Wave Event in the Midwestern US: A Top-Down Constraint From Moderate Resolution Imaging Spectroradiometer Water Vapor Retrieval 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (7)
作者:  Souri, Amir H.;  Wang, Huiqun;  Abad, Gonzalo Gonzalez;  Liu, Xiong;  Chance, Kelly
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/02
transpiration  water vapor  heat wave  corn sweat  extreme event  anthropogenic activity  
Electrical manipulation of a topological antiferromagnetic state 期刊论文
NATURE, 2020, 580 (7805) : 608-+
作者:  Chabon, Jacob J.;  Hamilton, Emily G.;  Kurtz, David M.;  Esfahani, Mohammad S.;  Moding, Everett J.;  Stehr, Henning;  Schroers-Martin, Joseph;  Nabet, Barzin Y.;  Chen, Binbin;  Chaudhuri, Aadel A.;  Liu, Chih Long;  Hui, Angela B.;  Jin, Michael C.;  Azad, Tej D.;  Almanza, Diego;  Jeon, Young-Jun;  Nesselbush, Monica C.;  Keh, Lyron Co Ting;  Bonilla, Rene F.;  Yoo, Christopher H.;  Ko, Ryan B.;  Chen, Emily L.;  Merriott, David J.;  Massion, Pierre P.;  Mansfield, Aaron S.;  Jen, Jin;  Ren, Hong Z.;  Lin, Steven H.;  Costantino, Christina L.;  Burr, Risa;  Tibshirani, Robert;  Gambhir, Sanjiv S.;  Berry, Gerald J.;  Jensen, Kristin C.;  West, Robert B.;  Neal, Joel W.;  Wakelee, Heather A.;  Loo, Billy W., Jr.;  Kunder, Christian A.;  Leung, Ann N.;  Lui, Natalie S.;  Berry, Mark F.;  Shrager, Joseph B.;  Nair, Viswam S.;  Haber, Daniel A.;  Sequist, Lecia V.;  Alizadeh, Ash A.;  Diehn, Maximilian
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/03

Room-temperature electrical switching of a topological antiferromagnetic state in polycrystalline Mn3Sn thin films is demonstrated using the same protocol as that used for conventional ferromagnetic metals.


Electrical manipulation of phenomena generated by nontrivial band topology is essential for the development of next-generation technology using topological protection. A Weyl semimetal is a three-dimensional gapless system that hosts Weyl fermions as low-energy quasiparticles(1-4). It has various exotic properties, such as a large anomalous Hall effect (AHE) and chiral anomaly, which are robust owing to the topologically protected Weyl nodes(1-16). To manipulate such phenomena, a magnetic version of Weyl semimetals would be useful for controlling the locations of Weyl nodes in the Brillouin zone. Moreover, electrical manipulation of antiferromagnetic Weyl metals would facilitate the use of antiferromagnetic spintronics to realize high-density devices with ultrafast operation(17,18). However, electrical control of a Weyl metal has not yet been reported. Here we demonstrate the electrical switching of a topological antiferromagnetic state and its detection by the AHE at room temperature in a polycrystalline thin film(19) of the antiferromagnetic Weyl metal Mn3Sn9,10,12,20, which exhibits zero-field AHE. Using bilayer devices composed of Mn3Sn and nonmagnetic metals, we find that an electrical current density of about 10(10) to 10(11) amperes per square metre induces magnetic switching in the nonmagnetic metals, with a large change in Hall voltage. In addition, the current polarity along the bias field and the sign of the spin Hall angle of the nonmagnetic metals-positive for Pt (ref. (21)), close to 0 for Cu and negative for W (ref. (22))-determines the sign of the Hall voltage. Notably, the electrical switching in the antiferromagnet is achieved with the same protocol as that used for ferromagnetic metals(23,24). Our results may lead to further scientific and technological advances in topological magnetism and antiferromagnetic spintronics.


  
Below-surface water mediates the response of African forests to reduced rainfall 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (3)
作者:  Madani, Nima;  Kimball, John S.;  Parazoo, Nicholas C.;  Ballantyne, Ashley P.;  Tagesson, Torbern;  Jones, Lucas A.;  Reichle, Rolf H.;  Palmer, Paul, I;  Velicogna, Isabella;  Bloom, A. Anthony;  Saatchi, Sassan;  Liu, Zhihua;  Geruo, A.
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/02
GPP  SIF  groundwater  soil moisture  
Tertiary lymphoid structures improve immunotherapy and survival in melanoma (vol 577, pg 561, 2020) 期刊论文
NATURE, 2020
作者:  Tang, Yanhao;  Li, Lizhong;  Li, Tingxin;  Xu, Yang;  Liu, Song;  Barmak, Katayun;  Watanabe, Kenji;  Taniguchi, Takashi;  MacDonald, Allan H.;  Shan, Jie;  Mak, Kin Fai
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/03

An Amendment to this paper has been published and can be accessed via a link at the top of the paper.