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IGF1R is an entry receptor for respiratory syncytial virus (vol 53, pg 861, 2020) 期刊论文
NATURE, 2020, 583 (7815) : E22-E22
作者:  Smith, Jacob A.;  Wilson, Katy B.;  Sonstrom, Reilly E.;  Kelleher, Patrick J.;  Welch, Kevin D.;  Pert, Emmit K.;  Westendorff, Karl S.;  Dickie, Diane A.;  Wang, Xiaoping;  Pate, Brooks H.;  Harman, W. Dean
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/03

An amendment to this paper has been published and can be accessed via a link at the top of the paper.


  
First direct observation of sea salt aerosol production from blowing snow above sea ice 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (4) : 2549-2578
作者:  Frey, Markus M.;  Norris, Sarah J.;  Brooks, Ian M.;  Anderson, Philip S.;  Nishimura, Kouichi;  Yang, Xin;  Jones, Anna E.;  Mastromonaco, Michelle G. Nerentorp;  Jones, David H.;  Wolff, Eric W.
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/02
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Temperature change as a driver of spatial patterns and long-term trends in chironomid (Insecta: Diptera) diversity 期刊论文
GLOBAL CHANGE BIOLOGY, 2019
作者:  Engels, Stefan;  Medeiros, Andrew S.;  Axford, Yarrow;  Brooks, Stephen J.;  Heiri, Oliver;  Luoto, Tomi P.;  Nazarova, Larisa;  Porinchu, David F.;  Quinlan, Roberto;  Self, Angela E.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
Arctic  biodiversity  climate warming  freshwater ecosystems  insects  palaeoecology  Quaternary  
Close-range remote sensing of Saturn's rings during Cassini's ring-grazing orbits and Grand Finale 期刊论文
SCIENCE, 2019, 364 (6445) : 1054-+
作者:  Tiscareno, Matthew S.;  Nicholson, Philip D.;  Cuzzi, Jeffrey N.;  Spilker, Linda J.;  Murray, Carl D.;  Hedman, Matthew M.;  Colwell, Joshua E.;  Burns, Joseph A.;  Brooks, Shawn M.;  Clark, Roger N.;  Cooper, Nicholas J.;  Deau, Estelle;  Ferrari, Cecile;  Filacchione, Gianrico;  Jerousek, Richard G.;  Le Mouelic, Stephane;  Morishima, Ryuji;  Pilorz, Stu;  Rodriguez, Sebastien;  Showalter, Mark R.;  Badman, Sarah V.;  Baker, Emily J.;  Buratti, Bonnie J.;  Baines, Kevin H.;  Sotin, Christophe
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
Predicting coral community recovery using multi-species population dynamics models 期刊论文
ECOLOGY LETTERS, 2019, 22 (4) : 605-615
作者:  Kayal, Mohsen;  Lenihan, Hunter S.;  Brooks, Andrew J.;  Holbrook, Sally J.;  Schmitt, Russell J.;  Kendall, Bruce E.
收藏  |  浏览/下载:5/0  |  提交时间:2019/04/09
Community recovery  coral reefs  density dependence  ecosystem function  elasticity analysis  integral projection model  life-history traits  multi-species demographic model  reassembly  size structure  
Hillslope Hydrology in Global Change Research and Earth System Modeling 期刊论文
WATER RESOURCES RESEARCH, 2019, 55 (2) : 1737-1772
作者:  Fan, Y.;  Clark, M.;  Lawrence, D. M.;  Swenson, S.;  Band, L. E.;  Brantley, S. L.;  Brooks, P. D.;  Dietrich, W. E.;  Flores, A.;  Grant, G.;  Kirchner, J. W.;  Mackay, D. S.;  McDonnell, J. J.;  Milly, P. C. D.;  Sullivan, P. L.;  Tague, C.;  Ajami, H.;  Chaney, N.;  Hartmann, A.;  Hazenberg, P.;  McNamara, J.;  Pelletier, J.;  Perket, J.;  Rouholahnejad-Freund, E.;  Wagener, T.;  Zeng, X.;  Beighley, E.;  Buzan, J.;  Huang, M.;  Livneh, B.;  Mohanty, B. P.;  Nijssen, B.;  Safeeq, M.;  Shen, C.;  van Verseveld, W.;  Volk, J.;  Yamazaki, D.
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/26
Earth System Model  hillslope hydrology  Critical Zone  vegetation distribution  global water  energy  carbon cycles  surface water-groundwater interaction  
Predicting coral community recovery using multi-species population dynamics models 期刊论文
ECOLOGY LETTERS, 2018, 21 (12) : 1790-1799
作者:  Kayal, Mohsen;  Lenihan, Hunter S.;  Brooks, Andrew J.;  Holbrook, Sally J.;  Schmitt, Russell J.;  Kendall, Bruce E.
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/09
Community recovery  coral reefs  density dependence  ecosystem function  elasticity analysis  integral projection model  life-history traits  multi-species demographic model  reassembly  size structure  
Thermal Emission From Saturn's Polar Cyclones 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2018, 45 (11) : 5312-5319
作者:  Achterberg, R. K.;  Flasar, F. M.;  Bjoraker, G. L.;  Hesman, B. E.;  Gorius, N. J. P.;  Mamoutkine, A. A.;  Fletcher, L. N.;  Segura, M. E.;  Edgington, S. G.;  Brooks, S. M.
收藏  |  浏览/下载:12/0  |  提交时间:2019/04/09
Plant controls on Late Quaternary whole ecosystem structure and function 期刊论文
ECOLOGY LETTERS, 2018, 21 (6) : 814-825
作者:  Jeffers, Elizabeth S.;  Whitehouse, Nicki J.;  Lister, Adrian;  Plunkett, Gill;  Barratt, Phil;  Smyth, Emma;  Lamb, Philip;  Dee, Michael W.;  Brooks, Stephen J.;  Willis, Katherine J.;  Froyd, Cynthia A.;  Watson, Jenny E.;  Bonsall, Michael B.
收藏  |  浏览/下载:22/0  |  提交时间:2019/04/09
Climate change  landscape burning  megafauna extinction  nutrient cycling  plant community composition  plant-plant interactions  plant-soil interactions