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Relocation planning must address voluntary immobility 期刊论文
NATURE CLIMATE CHANGE, 2020
作者:  Farbotko, Carol;  Dun, Olivia;  Thornton, Fanny;  McNamara, Karen E.;  McMichael, Celia
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/21
The relative importance of plasticity versus genetic differentiation in explaining between population differences; a meta-analysis 期刊论文
ECOLOGY LETTERS, 2020
作者:  Stamp, Megan A.;  Hadfield, Jarrod D.
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/14
Counter-gradient variation  Gene-flow  local adaptation  phenotypic plasticity  
Weather at the winter and stopover areas determines spring migration onset, progress, and advancements in Afro-Palearctic migrant birds 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (29) : 17056-17062
作者:  Haest, Birgen;  Hueppop, Ommo;  Bairlein, Franz
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/06
phenology  environmental plasticity  microevolution  behavioral flexibility  conservation  
Attitudes of urban residents towards environmental migration in Kenya and Vietnam 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (7) : 622-+
作者:  Spilker, Gabriele;  Nguyen, Quynh;  Koubi, Vally;  Bohmelt, Tobias
收藏  |  浏览/下载:3/0  |  提交时间:2020/06/29
Perception of climate migrants 期刊论文
NATURE CLIMATE CHANGE, 2020, 10 (7) : 600-601
作者:  McLeman, Robert
收藏  |  浏览/下载:2/0  |  提交时间:2020/06/29
Rapidly-migrating and internally-generated knickpoints can control submarine channel evolution 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Heijnen, Maarten S.;  Clare, Michael A.;  Cartigny, Matthieu J. B.;  Talling, Peter J.;  Hage, Sophie;  Lintern, D. Gwyn;  Stacey, Cooper;  Parsons, Daniel R.;  Simmons, Stephen M.;  Chen, Ye;  Sumner, Esther J.;  Dix, Justin K.;  Clarke, John E. Hughes
收藏  |  浏览/下载:13/0  |  提交时间:2020/06/22
Insights into the assembly and activation of the microtubule nucleator gamma-TuRC 期刊论文
NATURE, 2020, 578 (7795) : 467-+
作者:  Cyranoski, David
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/03

Microtubules are dynamic polymers of alpha- and beta-tubulin and have crucial roles in cell signalling, cell migration, intracellular transport and chromosome segregation(1). They assemble de novo from alpha beta-tubulin dimers in an essential process termed microtubule nucleation. Complexes that contain the protein gamma-tubulin serve as structural templates for the microtubule nucleation reaction(2). In vertebrates, microtubules are nucleated by the 2.2-megadalton gamma-tubulin ring complex (gamma-TuRC), which comprises gamma-tubulin, five related gamma-tubulin complex proteins (GCP2-GCP6) and additional factors(3). GCP6 is unique among the GCP proteins because it carries an extended insertion domain of unknown function. Our understanding of microtubule formation in cells and tissues is limited by a lack of high-resolution structural information on the gamma-TuRC. Here we present the cryo-electron microscopy structure of gamma-TuRC from Xenopus laevis at 4.8 angstrom global resolution, and identify a 14-spoked arrangement of GCP proteins and gamma-tubulins in a partially flexible open left-handed spiral with a uniform sequence of GCP variants. By forming specific interactions with other GCP proteins, the GCP6-specific insertion domain acts as a scaffold for the assembly of the gamma-TuRC. Unexpectedly, we identify actin as a bona fide structural component of the gamma-TuRC with functional relevance in microtubule nucleation. The spiral geometry of gamma-TuRC is suboptimal for microtubule nucleation and a controlled conformational rearrangement of the gamma-TuRC is required for its activation. Collectively, our cryo-electron microscopy reconstructions provide detailed insights into the molecular organization, assembly and activation mechanism of vertebrate gamma-TuRC, and will serve as a framework for the mechanistic understanding of fundamental biological processes associated with microtubule nucleation, such as meiotic and mitotic spindle formation and centriole biogenesis(4).


The cryo-EM structure of the gamma-tubulin ring complex (gamma-TuRC) from Xenopus laevis provides insights into the molecular organization of the complex, and shows that actin is a structural component that is functionally relevant to microtubule nucleation.


  
How canyons evolve by incision into bedrock: Rainbow Canyon, Death Valley National Park, United States 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (26) : 14730-14737
作者:  Zhang, Li;  Li, Tiejian;  Wang, Guangqian;  Kwang, Jeffrey S.;  Nittrouer, Jeffrey A.;  Fu, Xudong;  Parker, Gary
收藏  |  浏览/下载:10/0  |  提交时间:2020/06/22
canyon  bedrock  incision  uplift  knickpoint  
Enriched East Asian oxygen isotope of precipitation indicates reduced summer seasonality in regional climate and westerlies 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (26) : 14745-14750
作者:  Chiang, John C. H.;  Herman, Michael J.;  Yoshimura, Kei;  Fung, Inez Y.
收藏  |  浏览/下载:7/0  |  提交时间:2020/06/16
paleoclimate  monsoon  westerlies  East Asia  
Seasonal insect migrations: massive, influential, and overlooked 期刊论文
FRONTIERS IN ECOLOGY AND THE ENVIRONMENT, 2020
作者:  Satterfield, Dara A.;  Sillett, T. Scott;  Chapman, Jason W.;  Altizer, Sonia;  Marra, Peter P.
收藏  |  浏览/下载:8/0  |  提交时间:2020/08/18