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A Galactic-scale gas wave in the solar neighbourhood 期刊论文
NATURE, 2020, 578 (7794) : 237-+
作者:  Alves, Joao;  Zucker, Catherine;  Goodman, Alyssa A.;  Speagle, Joshua S.;  Meingast, Stefan;  Robitaille, Thomas;  Finkbeiner, Douglas P.;  Schlafly, Edward F.;  Green, Gregory M.
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/03

The three-dimensional structure of all cloud complexes in the solar neighbourhood is revealed, showing a narrow and coherent 2.7-kpc arrangement of dense gas, in disagreement with the Gould Belt model.


For the past 150 years, the prevailing view of the local interstellar medium has been based on a peculiarity known as the Gould Belt(1-4), an expanding ring of young stars, gas and dust, tilted about 20 degrees to the Galactic plane. However, the physical relationship between local gas clouds has remained unknown because the accuracy in distance measurements to such clouds is of the same order as, or larger than, their sizes(5-7). With the advent of large photometric surveys(8) and the astrometric survey(9), this situation has changed(10). Here we reveal the three-dimensional structure of all local cloud complexes. We find a narrow and coherent 2.7-kiloparsec arrangement of dense gas in the solar neighbourhood that contains many of the clouds thought to be associated with the Gould Belt. This finding is inconsistent with the notion that these clouds are part of a ring, bringing the Gould Belt model into question. The structure comprises the majority of nearby star-forming regions, has an aspect ratio of about 1:20 and contains about three million solar masses of gas. Remarkably, this structure appears to be undulating, and its three-dimensional shape is well described by a damped sinusoidal wave on the plane of the Milky Way with an average period of about 2 kiloparsecs and a maximum amplitude of about 160 parsecs.


  
Preparation of cyclohexene isotopologues and stereoisotopomers from benzene 期刊论文
NATURE, 2020, 581 (7808) : 288-+
作者:  Shimazaki, Yuya;  Schwartz, Ido;  Watanabe, Kenji;  Taniguchi, Takashi;  Kroner, Martin;  Imamoglu, Atac
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

The hydrogen isotopes deuterium (D) and tritium (T) have become essential tools in chemistry, biology and medicine(1). Beyond their widespread use in spectroscopy, mass spectrometry and mechanistic and pharmacokinetic studies, there has been considerable interest in incorporating deuterium into drug molecules(1). Deutetrabenazine, a deuterated drug that is promising for the treatment of Huntington'  s disease(2), was recently approved by the United States'  Food and Drug Administration. The deuterium kinetic isotope effect, which compares the rate of a chemical reaction for a compound with that for its deuterated counterpart, can be substantial(1,3,4). The strategic replacement of hydrogen with deuterium can affect both the rate of metabolism and the distribution of metabolites for a compound(5), improving the efficacy and safety of a drug. The pharmacokinetics of a deuterated compound depends on the location(s) of deuterium. Although methods are available for deuterium incorporation at both early and late stages of the synthesis of a drug(6,7), these processes are often unselective and the stereoisotopic purity can be difficult to measure(7,8). Here we describe the preparation of stereoselectively deuterated building blocks for pharmaceutical research. As a proof of concept, we demonstrate a four-step conversion of benzene to cyclohexene with varying degrees of deuterium incorporation, via binding to a tungsten complex. Using different combinations of deuterated and proteated acid and hydride reagents, the deuterated positions on the cyclohexene ring can be controlled precisely. In total, 52 unique stereoisotopomers of cyclohexene are available, in the form of ten different isotopologues. This concept can be extended to prepare discrete stereoisotopomers of functionalized cyclohexenes. Such systematic methods for the preparation of pharmacologically active compounds as discrete stereoisotopomers could improve the pharmacological and toxicological properties of drugs and provide mechanistic information related to their distribution and metabolism in the body.


Cyclohexene isotopologues and stereoisotopomers with varying degrees of deuteration are formed by binding a tungsten complex to benzene, which facilitates the selective incorporation of deuterium into any position on the ring.


  
Collisional cooling of ultracold molecules 期刊论文
NATURE, 2020, 580 (7802) : 197-+
作者:  Wang, Qinyang;  Wang, Yupeng;  Ding, Jingjin;  Wang, Chunhong;  Zhou, Xuehan;  Gao, Wenqing;  Huang, Huanwei;  Shao, Feng;  Liu, Zhibo
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/03

Since the original work on Bose-Einstein condensation(1,2), the use of quantum degenerate gases of atoms has enabled the quantum emulation of important systems in condensed matter and nuclear physics, as well as the study of many-body states that have no analogue in other fields of physics(3). Ultracold molecules in the micro- and nanokelvin regimes are expected to bring powerful capabilities to quantum emulation(4) and quantum computing(5), owing to their rich internal degrees of freedom compared to atoms, and to facilitate precision measurement and the study of quantum chemistry(6). Quantum gases of ultracold atoms can be created using collision-based cooling schemes such as evaporative cooling, but thermalization and collisional cooling have not yet been realized for ultracold molecules. Other techniques, such as the use of supersonic jets and cryogenic buffer gases, have reached temperatures limited to above 10 millikelvin(7,8). Here we show cooling of NaLi molecules to micro- and nanokelvin temperatures through collisions with ultracold Na atoms, with both molecules and atoms prepared in their stretched hyperfine spin states. We find a lower bound on the ratio of elastic to inelastic molecule-atom collisions that is greater than 50-large enough to support sustained collisional cooling. By employing two stages of evaporation, we increase the phase-space density of the molecules by a factor of 20, achieving temperatures as low as 220 nanokelvin. The favourable collisional properties of the Na-NaLi system could enable the creation of deeply quantum degenerate dipolar molecules and raises the possibility of using stretched spin states in the cooling of other molecules.


NaLi molecules are cooled to micro- and nanokelvin temperatures through collisions with ultracold Na atoms by using molecules and atoms in stretched hyperfine spin states and applying two evaporation stages.


  
The wide-binary origin of (2014) MU69-like Kuiper belt contact binaries 期刊论文
NATURE, 2020, 580 (7804) : 463-+
作者:  Jiao, Lin;  Howard, Sean;  Ran, Sheng;  Wang, Zhenyu;  Rodriguez, Jorge Olivares;  Sigrist, Manfred;  Wang, Ziqiang;  Butch, Nicholas P.;  Madhavan, Vidya
收藏  |  浏览/下载:71/0  |  提交时间:2020/07/03

Following its flyby and first imaging of the Pluto-Charon binary, the New Horizons spacecraft visited the Kuiper belt object (KBO) 2014 MU69 (also known as (486958) Arrokoth). The imaging showed MU69 to be a contact binary that rotates at a low spin period (15.92 hours), is made of two individual lobes connected by a narrow neck and has a high obliquity (about 98 degrees)(1), properties that are similar to those of other KBO contact binaries inferred through photometric observations(2). However, all scenarios suggested so far for the origins of such configurations(3-5) have failed to reproduce these properties and their probable frequent occurrence in the Kuiper belt. Here we show that semi-secular perturbations(6,7) operating on only ultrawide KBO binaries close to their stability limit can robustly lead to gentle, slow binary mergers at arbitrarily high obliquities but low rotational velocities, reproducing the characteristics of MU69 and other similar oblique contact binaries. Using N-body simulations, we find that approximately 15 per cent of all ultrawide binaries with a cosine-uniform inclination distribution(5,9) are likely to merge through this process. Moreover, we find that such mergers are sufficiently gentle to deform the shape of the KBO only slightly. The semi-secular contact binary formation channel not only explains the observed properties of MU69, but may also apply to other Kuiper belt or asteroid belt binaries and in the Solar System and extra-solar moon systems.


The high obliquity and low rotation period of the Kuiper belt object (2014) MU69 and other similar contact binaries is successfully reproduced from the collision and post-collision characteristics of initially wide binaries.


  
Temperature change as a driver of spatial patterns and long-term trends in chironomid (Insecta: Diptera) diversity 期刊论文
GLOBAL CHANGE BIOLOGY, 2019
作者:  Engels, Stefan;  Medeiros, Andrew S.;  Axford, Yarrow;  Brooks, Stephen J.;  Heiri, Oliver;  Luoto, Tomi P.;  Nazarova, Larisa;  Porinchu, David F.;  Quinlan, Roberto;  Self, Angela E.
收藏  |  浏览/下载:14/0  |  提交时间:2019/11/27
Arctic  biodiversity  climate warming  freshwater ecosystems  insects  palaeoecology  Quaternary  
The brighter side of climate change: How local oceanography amplified a lobster boom in the Gulf of Maine 期刊论文
GLOBAL CHANGE BIOLOGY, 2019, 25 (11) : 3906-3917
作者:  Goode, Andrew G.;  Brady, Damian C.;  Steneck, Robert S.;  Wahle, Richard A.
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
American lobster  biological thresholds  climate change  ocean warming  regional oceanography  thermal habitat  
Winter climate change and the poleward range expansion of a tropical invasive tree (Brazilian pepper-Schinus terebinthifolius) 期刊论文
GLOBAL CHANGE BIOLOGY, 2019
作者:  Osland, Michael J.;  Feher, Laura C.
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Brazilian pepper  climate change  freezing  invasive plant  range expansion  Schinus terebinthifolius  temperature threshold  tropicalization  
Characterising the biophysical, economic and social impacts of soil carbon sequestration as a greenhouse gas removal technology 期刊论文
GLOBAL CHANGE BIOLOGY, 2019
作者:  Sykes, Alasdair J.;  Macleod, Michael;  Eory, Vera;  Rees, Robert M.;  Payen, Florian;  Myrgiotis, Vasilis;  Williams, Mathew;  Sohi, Saran;  Hillier, Jon;  Moran, Dominic;  Manning, David A. C.;  Goglio, Pietro;  Seghetta, Michele;  Williams, Adrian;  Harris, Jim;  Dondini, Marta;  Walton, Jack;  House, Joanna;  Smith, Pete
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
4 per mille  agriculture  greenhouse gas removal  negative emissions  soil carbon sequestration  soil organic carbon  
Biogeographic variation in temperature sensitivity of decomposition in forest soils 期刊论文
GLOBAL CHANGE BIOLOGY, 2019
作者:  Li, Jinquan;  Nie, Ming;  Pendall, Elise;  Reich, Peter B.;  Pei, Junmin;  Noh, Nam Jin;  Zhu, Ting;  Li, Bo;  Fang, Changming
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
carbon cycle  carbon cycle modelling  carbon decomposition  climate change  forest  Q(10)  spatial heterogeneity  temperature sensitivity  
The acclimation of leaf photosynthesis of wheat and rice to seasonal temperature changes in T-FACE environments 期刊论文
GLOBAL CHANGE BIOLOGY, 2019
作者:  Cai, Chuang;  Li, Gang;  Di, Lijun;  Ding, Yunjie;  Fu, Lin;  Guo, Xuanhe;  Struik, Paul C.;  Pan, Genxing;  Li, Haozheng;  Chen, Weiping;  Luo, Weihong;  Yin, Xinyou
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
climate change  free-air CO2 enrichment  growth temperature  leaf nitrogen content  Oryza sativa L  photosynthesis model  stomatal conductance  Triticum aestivum L