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Population flow drives spatio-temporal distribution of COVID-19 in China 期刊论文
NATURE, 2020
作者:  Fernandez, Diego Carlos;  Komal, Ruchi;  Langel, Jennifer;  Ma, Jun;  Duy, Phan Q.;  Penzo, Mario A.;  Zhao, Haiqing;  Hattar, Samer
收藏  |  浏览/下载:69/0  |  提交时间:2020/07/03

Sudden, large-scale and diffuse human migration can amplify localized outbreaks of disease into widespread epidemics(1-4). Rapid and accurate tracking of aggregate population flows may therefore be epidemiologically informative. Here we use 11,478,484 counts of mobile phone data from individuals leaving or transiting through the prefecture of Wuhan between 1 January and 24 January 2020 as they moved to 296 prefectures throughout mainland China. First, we document the efficacy of quarantine in ceasing movement. Second, we show that the distribution of population outflow from Wuhan accurately predicts the relative frequency and geographical distribution of infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) until 19 February 2020, across mainland China. Third, we develop a spatio-temporal '  risk source'  model that leverages population flow data (which operationalize the risk that emanates from epidemic epicentres) not only to forecast the distribution of confirmed cases, but also to identify regions that have a high risk of transmission at an early stage. Fourth, we use this risk source model to statistically derive the geographical spread of COVID-19 and the growth pattern based on the population outflow from Wuhan  the model yields a benchmark trend and an index for assessing the risk of community transmission of COVID-19 over time for different locations. This approach can be used by policy-makers in any nation with available data to make rapid and accurate risk assessments and to plan the allocation of limited resources ahead of ongoing outbreaks.


Modelling of population flows in China enables the forecasting of the distribution of confirmed cases of COVID-19 and the identification of areas at high risk of SARS-CoV-2 transmission at an early stage.


  
A plant genetic network for preventing dysbiosis in the phyllosphere 期刊论文
NATURE, 2020, 580 (7805) : 653-+
作者:  van den Brink, Susanne C.;  Alemany, Anna;  van Batenburg, Vincent;  Moris, Naomi;  Blotenburg, Marloes;  Vivie, Judith;  Baillie-Johnson, Peter;  Nichols, Jennifer;  Sonnen, Katharina F.;  Martinez Arias, Alfonso;  van Oudenaarden, Alexander
收藏  |  浏览/下载:59/0  |  提交时间:2020/07/03

Mutations in genes involved in immune signalling and vesicle trafficking cause defects in the leaf microbiome of Arabidopsis thaliana that result in damage to leaf tissues, suggesting mechanisms by which terrestrial plants control the level and diversity of endophytic phyllosphere microbiota.


The aboveground parts of terrestrial plants, collectively called the phyllosphere, have a key role in the global balance of atmospheric carbon dioxide and oxygen. The phyllosphere represents one of the most abundant habitats for microbiota colonization. Whether and how plants control phyllosphere microbiota to ensure plant health is not well understood. Here we show that the Arabidopsis quadruple mutant (min7 fls2 efr cerk1  hereafter, mfec)(1), simultaneously defective in pattern-triggered immunity and the MIN7 vesicle-trafficking pathway, or a constitutively activated cell death1 (cad1) mutant, carrying a S205F mutation in a membrane-attack-complex/perforin (MACPF)-domain protein, harbour altered endophytic phyllosphere microbiota and display leaf-tissue damage associated with dysbiosis. The Shannon diversity index and the relative abundance of Firmicutes were markedly reduced, whereas Proteobacteria were enriched in the mfec and cad1(S205F) mutants, bearing cross-kingdom resemblance to some aspects of the dysbiosis that occurs in human inflammatory bowel disease. Bacterial community transplantation experiments demonstrated a causal role of a properly assembled leaf bacterial community in phyllosphere health. Pattern-triggered immune signalling, MIN7 and CAD1 are found in major land plant lineages and are probably key components of a genetic network through which terrestrial plants control the level and nurture the diversity of endophytic phyllosphere microbiota for survival and health in a microorganism-rich environment.


  
Importance and vulnerability of the world's water towers 期刊论文
NATURE, 2020, 577 (7790) : 364-+
作者:  Krebs, John R.;  Hassell, Michael
收藏  |  浏览/下载:49/0  |  提交时间:2020/04/16

Mountains are the water towers of the world, supplying a substantial part of both natural and anthropogenic water demands(1,2). They are highly sensitive and prone to climate change(3,4), yet their importance and vulnerability have not been quantified at the global scale. Here we present a global water tower index (WTI), which ranks all water towers in terms of their water-supplying role and the downstream dependence of ecosystems and society. For each water tower, we assess its vulnerability related to water stress, governance, hydropolitical tension and future climatic and socioeconomic changes. We conclude that the most important (highest WTI) water towers are also among the most vulnerable, and that climatic and socio-economic changes will affect them profoundly. This could negatively impact 1.9 billion people living in (0.3 billion) or directly downstream of (1.6 billion) mountainous areas. Immediate action is required to safeguard the future of the world'  s most important and vulnerable water towers.


  
Australian hot and dry extremes induced by weakenings of the stratospheric polar vortex 期刊论文
NATURE GEOSCIENCE, 2019, 12 (11) : 896-+
作者:  Lim, Eun-Pa;  Hendon, Harry H.;  Boschat, Ghyslaine;  Hudson, Debra;  Thompson, David W. J.;  Dowdy, Andrew J.;  Arblaster, Julie M.
收藏  |  浏览/下载:6/0  |  提交时间:2020/02/16
Torsional refrigeration by twisted, coiled, and supercoiled fibers 期刊论文
SCIENCE, 2019, 366 (6462) : 216-+
作者:  Wang, Run;  Fang, Shaoli;  Xiao, Yicheng;  Gao, Enlai;  Jiang, Nan;  Li, Yaowang;  Mou, Linlin;  Shen, Yanan;  Zhao, Wubin;  Li, Sitong;  Fonseca, Alexandre F.;  Galvao, Douglas S.;  Chen, Mengmeng;  He, Wenqian;  Yu, Kaiqing;  Lu, Hongbing;  Wang, Xuemin;  Qian, Dong;  Aliev, Ali E.;  Li, Na;  Haines, Carter S.;  Liu, Zhongsheng;  Mu, Jiuke;  Wang, Zhong;  Yin, Shougen;  Lima, Marcio D.;  An, Baigang;  Zhou, Xiang;  Liu, Zunfeng;  Baughman, Ray H.
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Shape regulation of high-index facet nanoparticles by dealloying 期刊论文
SCIENCE, 2019, 365 (6458) : 1159-+
作者:  Huang, Liliang;  Liu, Mohan;  Lin, Haixin;  Xu, Yaobin;  Wu, Jinsong;  Dravid, Vinayak P.;  Wolverton, Chris;  Mirkin, Chad A.
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Dynamic genetic regulation of gene expression during cellular differentiation 期刊论文
SCIENCE, 2019, 364 (6447) : 1287-1290
作者:  Strober, B. J.;  Elorbany, R.;  Rhodes, K.;  Krishnan, N.;  Tayeb, K.;  Battle, A.;  Gilad, Y.
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27
Stable Casimir equilibria and quantum trapping 期刊论文
SCIENCE, 2019, 364 (6444) : 984-+
作者:  Zhao, Rongkuo;  Li, Lin;  Yang, Sui;  Bao, Wei;  Xia, Yang;  Ashby, Paul;  Wang, Yuan;  Zhang, Xiang
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
Double-negative-index ceramic aerogels for thermal superinsulation 期刊论文
SCIENCE, 2019, 363 (6428) : 723-+
作者:  Xu, Xiang;  Zhang, Qiangqiang;  Hao, Menglong;  Hu, Yuan;  Lin, Zhaoyang;  Peng, Lele;  Wang, Tao;  Ren, Xuexin;  Wang, Chen;  Zhao, Zipeng;  Wan, Chengzhang;  Fei, Huilong;  Wang, Lei;  Zhu, Jian;  Sun, Hongtao;  Chen, Wenli;  Du, Tao;  Deng, Biwei;  Cheng, Gary J.;  Shakir, Imran;  Dames, Chris;  Fisher, Timothy S.;  Zhang, Xiang;  Li, Hui;  Huang, Yu;  Duan, Xiangfeng
收藏  |  浏览/下载:15/0  |  提交时间:2019/11/27
Rainfall variations in central Indo-Pacific over the past 2,700 y 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (35) : 17201-17206
作者:  Tan, Liangcheng;  Shen, Chuan-Chou;  Lowemark, Ludvig;  Chawchai, Sakonvan;  Edwards, R. Lawrence;  Cai, Yanjun;  Breitenbach, Sebastian F. M.;  Cheng, Hai J.;  Chou, Yu-Chen;  Duerrast, Helmut;  Partin, Judson W.;  Cai, Wenju;  Chabangborn, Akkaneewut;  Gao, Yongli;  Kwiecien, Ola;  Wu, Chung-Che;  Shi, Zhengguo;  Hsu, Huang-Hsiung;  Wohlfarth, Barbara
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/27
central Indo-Pacific  rainfall  ENSO  ITCZ  stalagmite