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Deep rotating convection generates the polar hexagon on Saturn 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (25) : 13991-13996
作者:  Yadav, Rakesh K.;  Bloxham, Jeremy
收藏  |  浏览/下载:5/0  |  提交时间:2020/06/16
planetary atmospheres  rotating convection  turbulence  
International evaluation of an AI system for breast cancer screening 期刊论文
NATURE, 2020, 577 (7788) : 89-+
作者:  McKinney, Scott Mayer;  Sieniek, Marcin;  Godbole, Varun;  Godwin, Jonathan;  Antropova, Natasha;  Ashrafian, Hutan;  Back, Trevor;  Chesus, Mary;  Corrado, Greg C.;  Darzi, Ara;  Etemadi, Mozziyar;  Garcia-Vicente, Florencia;  Gilbert, Fiona J.;  Halling-Brown, Mark;  Hassabis, Demis;  Jansen, Sunny;  Karthikesalingam, Alan;  Kelly, Christopher J.;  King, Dominic;  Ledsam, Joseph R.;  Melnick, David;  Mostofi, Hormuz;  Peng, Lily;  Reicher, Joshua Jay;  Romera-Paredes, Bernardino;  Sidebottom, Richard;  Suleyman, Mustafa;  Tse, Daniel;  Young, Kenneth C.;  De Fauw, Jeffrey;  Shetty, Shravya
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/03

Screening mammography aims to identify breast cancer at earlier stages of the disease, when treatment can be more successful(1). Despite the existence of screening programmes worldwide, the interpretation of mammograms is affected by high rates of false positives and false negatives(2). Here we present an artificial intelligence (AI) system that is capable of surpassing human experts in breast cancer prediction. To assess its performance in the clinical setting, we curated a large representative dataset from the UK and a large enriched dataset from the USA. We show an absolute reduction of 5.7% and 1.2% (USA and UK) in false positives and 9.4% and 2.7% in false negatives. We provide evidence of the ability of the system to generalize from the UK to the USA. In an independent study of six radiologists, the AI system outperformed all of the human readers: the area under the receiver operating characteristic curve (AUC-ROC) for the AI system was greater than the AUC-ROC for the average radiologist by an absolute margin of 11.5%. We ran a simulation in which the AI system participated in the double-reading process that is used in the UK, and found that the AI system maintained non-inferior performance and reduced the workload of the second reader by 88%. This robust assessment of the AI system paves the way for clinical trials to improve the accuracy and efficiency of breast cancer screening.


  
Detected climatic change in global distribution of tropical cyclones 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (20) : 10706-10714
作者:  Murakami, Hiroyuki;  Delworth, Thomas L.;  Cooke, William F.;  Zhao, Ming;  Xiang, Baoqiang;  Hsu, Pang-Chi
收藏  |  浏览/下载:6/0  |  提交时间:2020/05/13
tropical cyclones  detection and attribution  large-ensemble simulations  climate change  spatial pattern  
Temperate rainforests near the South Pole during peak Cretaceous warmth 期刊论文
NATURE, 2020, 580 (7801) : 81-+
作者:  Johann P. Klages;  Ulrich Salzmann;  Torsten Bickert;  Claus-Dieter Hillenbrand;  Karsten Gohl;  Gerhard Kuhn;  Steven M. Bohaty;  ;  rgen Titschack;  Juliane Mü;  ller;  Thomas Frederichs;  Thorsten Bauersachs;  Werner Ehrmann;  Tina van de Flierdt;  Patric Simõ;  es Pereira;  Robert D. Larter;  Gerrit Lohmann;  Igor Niezgodzki;  Gabriele Uenzelmann-Neben;  Maximilian Zundel;  Cornelia Spiegel;  Chris Mark;  David Chew;  Jane E. Francis;  Gernot Nehrke;  Florian Schwarz;  James A. Smith;  Tim Freudenthal;  Oliver Esper;  Heiko Pä;  like;  Thomas A. Ronge;  Ricarda Dziadek
收藏  |  浏览/下载:13/0  |  提交时间:2020/05/13

The mid-Cretaceous period was one of the warmest intervals of the past 140 million years(1-5), driven by atmospheric carbon dioxide levels of around 1,000 parts per million by volume(6). In the near absence of proximal geological records from south of the Antarctic Circle, it is disputed whether polar ice could exist under such environmental conditions. Here we use a sedimentary sequence recovered from the West Antarctic shelf-the southernmost Cretaceous record reported so far-and show that a temperate lowland rainforest environment existed at a palaeolatitude of about 82 degrees S during the Turonian-Santonian age (92 to 83 million years ago). This record contains an intact 3-metre-long network of in situ fossil roots embedded in a mudstone matrix containing diverse pollen and spores. A climate model simulation shows that the reconstructed temperate climate at this high latitude requires a combination of both atmospheric carbon dioxide concentrations of 1,120-1,680 parts per million by volume and a vegetated land surface without major Antarctic glaciation, highlighting the important cooling effect exerted by ice albedo under high levels of atmospheric carbon dioxide.


  
Simulation of Hubbard model physics in WSe2/WS2 moire superlattices 期刊论文
NATURE, 2020, 579 (7799) : 353-+
作者:  Stein, Reed M.;  Kang, Hye Jin;  McCorvy, John D.;  Glatfelter, Grant C.;  Jones, Anthony J.;  Che, Tao;  Slocum, Samuel;  Huang, Xi-Ping;  Savych, Olena;  Moroz, Yurii S.;  Stauch, Benjamin;  Johansson, Linda C.;  Cherezov, Vadim;  Kenakin, Terry;  Irwin, John J.;  Shoichet, Brian K.;  Roth, Bryan L.;  Dubocovich, Margarita L.
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/03

Study of WSe2/WS2 moire superlattices reveals the phase diagram of the triangular-lattice Hubbard model, including a Mott insulating state at half-filling and a possible magnetic quantum phase transition near 0.6 filling.


The Hubbard model, formulated by physicist John Hubbard in the 1960s(1), is a simple theoretical model of interacting quantum particles in a lattice. The model is thought to capture the essential physics of high-temperature superconductors, magnetic insulators and other complex quantum many-body ground states(2,3). Although the Hubbard model provides a greatly simplified representation of most real materials, it is nevertheless difficult to solve accurately except in the one-dimensional case(2,3). Therefore, the physical realization of the Hubbard model in two or three dimensions, which can act as an analogue quantum simulator (that is, it can mimic the model and simulate its phase diagram and dynamics(4,5)), has a vital role in solving the strong-correlation puzzle, namely, revealing the physics of a large number of strongly interacting quantum particles. Here we obtain the phase diagram of the two-dimensional triangular-lattice Hubbard model by studying angle-aligned WSe2/WS2 bilayers, which form moire superlattices(6) because of the difference between the lattice constants of the two materials. We probe the charge and magnetic properties of the system by measuring the dependence of its optical response on an out-of-plane magnetic field and on the gate-tuned carrier density. At half-filling of the first hole moire superlattice band, we observe a Mott insulating state with antiferromagnetic Curie-Weiss behaviour, as expected for a Hubbard model in the strong-interaction regime(2,3,7-9). Above half-filling, our experiment suggests a possible quantum phase transition from an antiferromagnetic to a weak ferromagnetic state at filling factors near 0.6. Our results establish a new solid-state platform based on moire superlattices that can be used to simulate problems in strong-correlation physics that are described by triangular-lattice Hubbard models.


  
Self-verifying variational quantum simulation of lattice models (vol 569, pg 355, 2020) 期刊论文
NATURE, 2020, 580 (7804) : E9-E9
作者:  Rumyantsev, Oleg I.;  Lecoq, Jerome A.;  Hernandez, Oscar;  Zhang, Yanping;  Savall, Joan;  Chrapkiewicz, Radoslaw;  Li, Jane;  Zeng, Hongkui;  Ganguli, Surya;  Schnitzer, Mark J.
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/03
Operation of a silicon quantum processor unit cell above one kelvin 期刊论文
NATURE, 2020, 580 (7803) : 350-+
作者:  Han, Kyuho;  Pierce, Sarah E.;  Li, Amy;  Spees, Kaitlyn;  Anderson, Grace R.;  Seoane, Jose A.;  Lo, Yuan-Hung;  Dubreuil, Michael;  Olivas, Micah;  Kamber, Roarke A.;  Wainberg, Michael;  Kostyrko, Kaja;  Kelly, Marcus R.;  Yousefi, Maryam;  Simpkins, Scott W.;  Yao, David
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

Quantum computers are expected to outperform conventional computers in several important applications, from molecular simulation to search algorithms, once they can be scaled up to large numbers-typically millions-of quantum bits (qubits)(1-3). For most solid-state qubit technologies-for example, those using superconducting circuits or semiconductor spins-scaling poses a considerable challenge because every additional qubit increases the heat generated, whereas the cooling power of dilution refrigerators is severely limited at their operating temperature (less than 100 millikelvin)(4-6). Here we demonstrate the operation of a scalable silicon quantum processor unit cell comprising two qubits confined to quantum dots at about 1.5 kelvin. We achieve this by isolating the quantum dots from the electron reservoir, and then initializing and reading the qubits solely via tunnelling of electrons between the two quantum dots(7-9). We coherently control the qubits using electrically driven spin resonance(10,11) in isotopically enriched silicon(12 28)Si, attaining single-qubit gate fidelities of 98.6 per cent and a coherence time of 2 microseconds during '  hot'  operation, comparable to those of spin qubits in natural silicon at millikelvin temperatures(13-16). Furthermore, we show that the unit cell can be operated at magnetic fields as low as 0.1 tesla, corresponding to a qubit control frequency of 3.5 gigahertz, where the qubit energy is well below the thermal energy. The unit cell constitutes the core building block of a full-scale silicon quantum computer and satisfies layout constraints required by error-correction architectures(8),(17). Our work indicates that a spin-based quantum computer could be operated at increased temperatures in a simple pumped He-4 system (which provides cooling power orders of magnitude higher than that of dilution refrigerators), thus potentially enabling the integration of classical control electronics with the qubit array(18,19).


  
Constraint on the matter-antimatter symmetry-violating phase in neutrino oscillations 期刊论文
NATURE, 2020, 580 (7803) : 339-+
作者:  Houben, Lothar;  Weissman, Haim;  Wolf, Sharon G.;  Rybtchinski, Boris
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/03

The charge-conjugation and parity-reversal (CP) symmetry of fundamental particles is a symmetry between matter and antimatter. Violation of this CP symmetry was first observed in 1964(1), and CP violation in the weak interactions of quarks was soon established(2). Sakharov proposed(3) that CP violation is necessary to explain the observed imbalance of matter and antimatter abundance in the Universe. However, CP violation in quarks is too small to support this explanation. So far, CP violation has not been observed in non-quark elementary particle systems. It has been shown that CP violation in leptons could generate the matter-antimatter disparity through a process called leptogenesis(4). Leptonic mixing, which appears in the standard model'  s charged current interactions(5,6), provides a potential source of CP violation through a complex phase dCP, which is required by some theoretical models of leptogenesis(7-9). This CP violation can be measured in muon neutrino to electron neutrino oscillations and the corresponding antineutrino oscillations, which are experimentally accessible using accelerator-produced beams as established by the Tokai-to-Kamioka (T2K) and NOvA experiments(10,11). Until now, the value of dCP has not been substantially constrained by neutrino oscillation experiments. Here we report a measurement using long-baseline neutrino and antineutrino oscillations observed by the T2K experiment that shows a large increase in the neutrino oscillation probability, excluding values of dCP that result in a large increase in the observed antineutrino oscillation probability at three standard deviations (3 sigma). The 3 sigma confidence interval for delta(CP), which is cyclic and repeats every 2p, is [-3.41, -0.03] for the so-called normal mass ordering and [-2.54, -0.32] for the inverted mass ordering. Our results indicate CP violation in leptons and our method enables sensitive searches for matter-antimatter asymmetry in neutrino oscillations using accelerator-produced neutrino beams. Future measurements with larger datasets will test whether leptonic CP violation is larger than the CP violation in quarks.


  
Submicrosecond entangling gate between trapped ions via Rydberg interaction 期刊论文
NATURE, 2020, 580 (7803) : 345-+
作者:  Chatterjee, Sourav;  Guidi, Mara;  Seeberger, Peter H.;  Gilmore, Kerry
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/03

Generating quantum entanglement in large systems on timescales much shorter than the coherence time is key to powerful quantum simulation and computation. Trapped ions are among the most accurately controlled and best isolated quantum systems(1) with low-error entanglement gates operated within tens of microseconds using the vibrational motion of few-ion crystals(2,3). To exceed the level of complexity tractable by classical computers the main challenge is to realize fast entanglement operations in crystals made up of many ions (large ion crystals)(4). The strong dipole-dipole interactions in polar molecule(5) and Rydberg atom(6,7) systems allow much faster entangling gates, yet stable state-independent confinement comparable with trapped ions needs to be demonstrated in these systems(8). Here we combine the benefits of these approaches: we report a two-ion entangling gate with 700-nanosecond gate time that uses the strong dipolar interaction between trapped Rydberg ions, which we use to produce a Bell state with 78 per cent fidelity. The sources of gate error are identified and a total error of less than 0.2 per cent is predicted for experimentally achievable parameters. Furthermore, we predict that residual coupling to motional modes contributes an approximate gate error of 10(-4) in a large ion crystal of 100 ions. This provides a way to speed up and scale up trapped-ion quantum computers and simulators substantially.


  
African climate response to orbital and glacial forcing in 140,000-y simulation with implications for early modern human environments 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (5) : 2255-2264
作者:  Kutzbach, John E.;  Guan, Jian;  He, Feng;  Cohen, Andrew S.;  Orland, Ian J.;  Chen, Guangshan
收藏  |  浏览/下载:16/0  |  提交时间:2020/05/13
paleoclimate  Africa  climate modeling  glacial and orbital forcing  human dispersal