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DOI | 10.1289/EHP9824 |
Exposure to during Pregnancy and Fetal Growth in Eastern Massachusetts, USA | |
Michael Leung; Marc G. Weisskopf; Francine Laden; Brent A. Coull; Anna M. Modest; Michele R. Hacker; Blair J. Wylie; Yaguang Wei; Joel Schwartz; Stefania Papatheodorou | |
2022-01-06 | |
发表期刊 | Environmental Health Perspectives |
出版年 | 2022 |
英文摘要 | AbstractBackground:Prior studies have examined the association between fine particulate matter [PM in aerodynamic diameter ()] and fetal growth with either limited spatial or temporal resolution. Objectives:In this study, we examined the association between exposure during pregnancy and fetal growth measures (ultrasound parameters and birth weight) in a pregnancy cohort using spatiotemporally resolved in Eastern Massachusetts, USA. Methods:We used ultrasound measures of biparietal diameter (BPD), head circumference, femur length, and abdominal circumference (AC), in addition to birth weight, from 9,446 pregnancies that were delivered at the Beth Israel Deaconess Medical Center from 2011–2016. We used linear mixed-effects models to examine the associations of in two exposure windows (the first 16 wk of pregnancy and the cumulative exposure up until the assessment of fetal growth) with anatomic scans (ultrasound ), growth scans (ultrasound ), and birth weight. All models were adjusted for sociodemographic characteristics, long-term trends, and temperature. Results:Higher exposure in the first 16 wk was associated with smaller fetal growth measures, where associations were particularly strong for BPD, AC, and birth weight. For example, a increase in was associated with a lower mean BPD -score of (95% CI: , ) before 24 wk, a lower mean AC -score of (95% CI: , ) after 24 wk, and a lower mean birth weight -score of (95% CI: , ). Analyses examining the associations with cumulative exposure up until the assessment of fetal growth produced attenuated associations. Conclusions:Higher gestational exposure to was associated with smaller fetal growth measures at levels below the current national standards. https://doi.org/10.1289/EHP9824 |
领域 | 资源环境 |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/345051 |
专题 | 资源环境科学 |
推荐引用方式 GB/T 7714 | Michael Leung,Marc G. Weisskopf,Francine Laden,et al. Exposure to during Pregnancy and Fetal Growth in Eastern Massachusetts, USA[J]. Environmental Health Perspectives,2022. |
APA | Michael Leung.,Marc G. Weisskopf.,Francine Laden.,Brent A. Coull.,Anna M. Modest.,...&Stefania Papatheodorou.(2022).Exposure to during Pregnancy and Fetal Growth in Eastern Massachusetts, USA.Environmental Health Perspectives. |
MLA | Michael Leung,et al."Exposure to during Pregnancy and Fetal Growth in Eastern Massachusetts, USA".Environmental Health Perspectives (2022). |
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