GSTDTAP  > 气候变化
DOI10.1126/science.abh1558
Spatiotemporal pattern of COVID-19 spread in Brazil
Marcia C. Castro; Sun Kim; Lorena Barberia; Ana Freitas Ribeiro; Susie Gurzenda; Karina Braga Ribeiro; Erin Abbott; Jeffrey Blossom; Beatriz Rache; Burton H. Singer
2021-05-21
发表期刊Science
出版年2021
英文摘要Despite an extensive network of primary care availability, Brazil has suffered profoundly during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Using daily data from state health offices, Castro et al. analyzed the pattern of spread of COVID-19 cases and deaths in the country from February to October 2020. Clusters of deaths before cases became apparent indicated unmitigated spread. SARS-CoV-2 circulated undetected in Brazil for more than a month as it spread north from Sã o Paulo. In Manaus, transmission reached unprecedented levels after a momentary respite in mid-2020. Faria et al. tracked the evolution of a new, more aggressive lineage called P.1, which has 17 mutations, including three (K417T, E484K, and N501Y) in the spike protein. After a period of accelerated evolution, this variant emerged in Brazil during November 2020. Coupled with the emergence of P.1, disease spread was accelerated by stark local inequalities and political upheaval, which compromised a prompt federal response. Science , abh1558 and abh2644, this issue p. [821][1] and p. [815][2] Brazil has been severely hit by COVID-19, with rapid spatial spread of both cases and deaths. We used daily data on reported cases and deaths to understand, measure, and compare the spatiotemporal pattern of the spread across municipalities. Indicators of clustering, trajectories, speed, and intensity of the movement of COVID-19 to interior areas, combined with indices of policy measures, show that although no single narrative explains the diversity in the spread, an overall failure of implementing prompt, coordinated, and equitable responses in a context of stark local inequalities fueled disease spread. This resulted in high and unequal infection and mortality burdens. With a current surge in cases and deaths and several variants of concern in circulation, failure to mitigate the spread could further aggravate the burden. [1]: /lookup/doi/10.1126/science.abh1558 [2]: /lookup/doi/10.1126/science.abh2644
领域气候变化 ; 资源环境
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文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/328823
专题气候变化
资源环境科学
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Marcia C. Castro,Sun Kim,Lorena Barberia,et al. Spatiotemporal pattern of COVID-19 spread in Brazil[J]. Science,2021.
APA Marcia C. Castro.,Sun Kim.,Lorena Barberia.,Ana Freitas Ribeiro.,Susie Gurzenda.,...&Burton H. Singer.(2021).Spatiotemporal pattern of COVID-19 spread in Brazil.Science.
MLA Marcia C. Castro,et al."Spatiotemporal pattern of COVID-19 spread in Brazil".Science (2021).
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