Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1111/ele.12890 |
The impact of host genetic diversity on virus evolution and emergence | |
Rodriguez-Nevado, Cristina1; Lam, Tommy T-Y2; Holmes, Edward C.3,4; Pagan, Israel1 | |
2018-02-01 | |
发表期刊 | ECOLOGY LETTERS
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ISSN | 1461-023X |
EISSN | 1461-0248 |
出版年 | 2018 |
卷号 | 21期号:2页码:253-263 |
文章类型 | Article |
语种 | 英语 |
国家 | Spain; Peoples R China; Australia |
英文摘要 | Accumulating evidence indicates that biodiversity has an important impact on parasite evolution and emergence. The vast majority of studies in this area have only considered the diversity of species within an environment as an overall measure of biodiversity, overlooking the role of genetic diversity within a particular host species. Although theoretical models propose that host genetic diversity in part shapes that of the infecting parasite population, and hence modulates the risk of parasite emergence, this effect has seldom been tested empirically. Using Rabies virus (RABV) as a model parasite, we provide evidence that greater host genetic diversity increases both parasite genetic diversity and the likelihood of a host being a donor in RABV cross-species transmission events. We conclude that host genetic diversity may be an important determinant of parasite evolution and emergence. |
英文关键词 | Biodiversity host genetic diversity parasite emergence rabies virus virus evolution |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000425823900011 |
WOS关键词 | EMERGING INFECTIOUS-DISEASES ; RABIES VIRUS ; BEGOMOVIRUS POPULATIONS ; LOCAL ADAPTATION ; COEVOLUTION ; ESTABLISHMENT ; SHIFTS ; SEX |
WOS类目 | Ecology |
WOS研究方向 | Environmental Sciences & Ecology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/31440 |
专题 | 资源环境科学 |
作者单位 | 1.Univ Politecn Madrid, Ctr Biotecnol & Genom Plantas, Inst Nacl Invest & Tecnol Agr Alimentaria, Madrid 28223, Spain; 2.Univ Hong Kong, Sch Publ Hlth, Ctr Influenza Res, State Key Lab Emerging Infect Dis, Hong Kong, Hong Kong, Peoples R China; 3.Univ Sydney, Marie Bashir Inst Infect Dis & Biosecur, Charles Perkins Ctr, Sch Life & Environm Sci, Sydney, NSW 2006, Australia; 4.Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia |
推荐引用方式 GB/T 7714 | Rodriguez-Nevado, Cristina,Lam, Tommy T-Y,Holmes, Edward C.,et al. The impact of host genetic diversity on virus evolution and emergence[J]. ECOLOGY LETTERS,2018,21(2):253-263. |
APA | Rodriguez-Nevado, Cristina,Lam, Tommy T-Y,Holmes, Edward C.,&Pagan, Israel.(2018).The impact of host genetic diversity on virus evolution and emergence.ECOLOGY LETTERS,21(2),253-263. |
MLA | Rodriguez-Nevado, Cristina,et al."The impact of host genetic diversity on virus evolution and emergence".ECOLOGY LETTERS 21.2(2018):253-263. |
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