Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1111/ele.12829 |
Age-specific infectious period shapes dynamics of pneumonia in bighorn sheep | |
Plowright, Raina K.1; Manlove, Kezia R.2; Besser, Thomas E.2; Paez, David J.1; Andrews, Kimberly R.3; Matthews, Patrick E.4; Waits, Lisette P.3; Hudson, Peter J.5; Cassirer, E. Frances6 | |
2017-10-01 | |
发表期刊 | ECOLOGY LETTERS |
ISSN | 1461-023X |
EISSN | 1461-0248 |
出版年 | 2017 |
卷号 | 20期号:10 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | Superspreading, the phenomenon where a small proportion of individuals contribute disproportionately to new infections, has profound effects on disease dynamics. Superspreading can arise through variation in contacts, infectiousness or infectious periods. The latter has received little attention, yet it drives the dynamics of many diseases of critical public health, livestock health and conservation concern. Here, we present rare evidence of variation in infectious periods underlying a superspreading phenomenon in a free-ranging wildlife system. We detected persistent infections of Mycoplasma ovipneumoniae, the primary causative agent of pneumonia in bighorn sheep (Ovis canadensis), in a small number of older individuals that were homozygous at an immunologically relevant genetic locus. Interactions among age-structure, genetic composition and infectious periods may drive feedbacks in disease dynamics that determine the magnitude of population response to infection. Accordingly, variation in initial conditions may explain divergent population responses to infection that range from recovery to catastrophic decline and extirpation. |
英文关键词 | bighorn sheep disease dynamics feedback mechanism Mycoplasma ovipneumoniae pathogen persistence persistent carriage pneumonia supershedder superspreader wildlife health |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000411035600011 |
WOS关键词 | MAJOR HISTOCOMPATIBILITY COMPLEX ; MYCOPLASMA-OVIPNEUMONIAE ; LEPTOSPIRA-INTERROGANS ; RESPIRATORY-DISEASE ; PARASITE RESISTANCE ; OVIS-ARIES ; TRANSMISSION ; CARRIAGE ; PERSISTENCE ; POPULATION |
WOS类目 | Ecology |
WOS研究方向 | Environmental Sciences & Ecology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/31316 |
专题 | 资源环境科学 |
作者单位 | 1.Montana State Univ, Dept Microbiol & Immunol, 109 Lewis Hall, Bozeman, MT 59717 USA; 2.Washington State Univ, Dept Vet Microbiol & Pathol, Pullman, WA 99164 USA; 3.Univ Idaho, Dept Fish & Wildlife Sci, 875 Perimeter Dr MS 1136, Moscow, ID 83844 USA; 4.Oregon Dept Fish & Wildlife, 65495 Alder Slope Rd, Enterprise, OR 97828 USA; 5.Penn State Univ, Ctr Infect Dis Dynam, 201 Life Sci Bldg, University Pk, PA 16802 USA; 6.Idaho Dept Fish & Game, 3316 16th St, Lewiston, ID 83501 USA |
推荐引用方式 GB/T 7714 | Plowright, Raina K.,Manlove, Kezia R.,Besser, Thomas E.,et al. Age-specific infectious period shapes dynamics of pneumonia in bighorn sheep[J]. ECOLOGY LETTERS,2017,20(10). |
APA | Plowright, Raina K..,Manlove, Kezia R..,Besser, Thomas E..,Paez, David J..,Andrews, Kimberly R..,...&Cassirer, E. Frances.(2017).Age-specific infectious period shapes dynamics of pneumonia in bighorn sheep.ECOLOGY LETTERS,20(10). |
MLA | Plowright, Raina K.,et al."Age-specific infectious period shapes dynamics of pneumonia in bighorn sheep".ECOLOGY LETTERS 20.10(2017). |
条目包含的文件 | 条目无相关文件。 |
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