![Family around the table](http://www.imperial.ac.uk/ImageCropToolT4/imageTool/uploaded-images/newseventsimage_1606491780554_mainnews2012_x1.jpg)
Global S&T Development Trend Analysis Platform of Resources and Environment
COVID-19 spread in different social settings - new Imperial report | |
admin | |
2020-11-27 | |
发布年 | 2020 |
语种 | 英语 |
国家 | 英国 |
领域 | 资源环境 |
正文(英文) | ![]() ![]() In a global analysis of where SARS-CoV-2 transmission takes place, households show the highest transmission rates. The report, from the Imperial College London COVID-19 Response Team in collaboration with multiple partners. also revealed that:
The research team conducted a systematic review to estimate the secondary attack rate SAR (probability of onward infection from one infected individual among a defined group of close contacts such as a family group), and the observed reproduction number Robs (the observed average number of secondary cases per index case). The report identified 97 studies, 45 of which met inclusion criteria for meta-analysis. With many countries continuing to recommend “stay-at-home” measures, the upcoming festive season and with cases isolating inside households, our results show it is likely that this location will continue to be important in sustaining transmission Hayley Thompson Study author Understanding where transmission of SARS-CoV-2 takes place is critical to effectively targeting interventions, but evidence of transmission rates in different settings remains limited. After analysing data from a number of settings including households, social gatherings with friends and family, travel, healthcare, workplace and casual close contacts (e.g. strangers during shopping at a supermarket), researchers found that households show the highest transmission rates with a 21.1% (95% CI: 17.4%-24.8%) pooled secondary attack rate and 0.96 (95% CI: 0.67-1.32) pooled observed reproduction number. The team also find that the chance of one household member infecting another is significantly higher when the duration of household exposure is more than 5 days compared to 5 days or less. The researchers also point out that the majority of studies included in the pooled analysis came from China, where strict control policies were implemented which could limit the generalisability of estimates. Infection risk from friends and familySecondary attack rates related to familiar and prolonged close contacts were higher (such as social events with family and friends, 5.9% (95% CI: 3.8%-8.1%) than those related to low-risk casual contacts (such as strangers, 1.2%, 95% CI: 0.3%-2.1%). In addition, where the initial case was asymptomatic, the secondary attack rate was estimated to be two thirds lower (3.5%, 95% CI: 0.0%-6.4%) than when the index case had symptoms (12.8%, 95% CI: 8.9%-16.7%, p = <0.001). Understanding the conditions where transmission is more likely to occur is essential in guiding policy interventions to reduce transmission whilst balancing the economic impact Andria Mousa Study author The research team looked for differences in transmission by age; there was moderate evidence of less transmission occurring both from and to individuals under 20 years of age in the household context, but insufficient data to determine whether this held in other settings. Prolonged contact in households and in settings with familiar close contacts increases the potential for transmission of SARS-CoV-2. Additionally, the differences observed in transmissibility by symptom status of index cases (i.e whether someone is symptomatic or asymptomatic) and the potential for differing transmissibility by age, has important implications for outbreak control strategies - such as contact tracing, testing, and rapid isolation of cases. Contact tracing and testing crucialResearchers note there were limited data reporting transmission in workplaces, schools, and care-homes, highlighting the need for further research in these settings. Hayley Thompson, report author from Imperial College London said: This analysis provides some of the first evidence that asymptomatic infections are substantially less infectious than symptomatic cases Professor Neil Ferguson Study author Our review examines differences in transmission potential by contact type, setting and index case characteristics, to help inform how public health interventions can be better targeted in the coming months. With many countries continuing to recommend “stay-at-home” measures, the upcoming festive season and with cases isolating inside households, our results show it is likely that this location will continue to be important in sustaining transmission. The differences we observed in transmissibility by symptom status of index cases and duration of exposure have important implications for outbreak control strategies, highlighting how contact tracing, testing and rapid isolation of cases will be crucial. Notably the number of studies we identified from large scale contract tracing studies was limited and highlights the need for continued research into further understanding the locations and types of contact that facilitate transmission, especially in schools and workplaces.” Andria Mousa, report author from Imperial College London said: Professor Neil Ferguson, report author from Imperial College London added: “This analysis provides some of the first evidence that asymptomatic infections are substantially less infectious than symptomatic cases. It also reinforces growing evidence of the importance of household transmission, especially in the context where symptomatic cases are not isolated outside the home.” - The full report can be found on this link: https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-38-transmission/ The work is presented in the latest report from the WHO Collaborating Centre for Infectious Disease Modelling within the MRC Centre for Global Infectious Disease Analysis, Jameel Institute (J-IDEA), Imperial College London. Since the emergence of the new coronavirus (COVID-19) in December 2019, the Imperial College COVID-19 Response Team has adopted a policy of immediately sharing research findings on the developing pandemic. |
URL | 查看原文 |
来源平台 | Imperial College London |
文献类型 | 新闻 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/305361 |
专题 | 资源环境科学 |
推荐引用方式 GB/T 7714 | admin. COVID-19 spread in different social settings - new Imperial report. 2020. |
条目包含的文件 | 条目无相关文件。 |
个性服务 |
推荐该条目 |
保存到收藏夹 |
查看访问统计 |
导出为Endnote文件 |
谷歌学术 |
谷歌学术中相似的文章 |
[admin]的文章 |
百度学术 |
百度学术中相似的文章 |
[admin]的文章 |
必应学术 |
必应学术中相似的文章 |
[admin]的文章 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论